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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class
for sale
near
Delaware, OH
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz E-Class E 350 4MATIC
Vehicle information
Features
Reviews
Great they were fast with my service I waited for my car
Great they were fast with my service I waited for my car it was awesome
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰






Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350 4MATIC
Vehicle information
Features
Reviews
Christian Wilkoski was very helpful with timing and
Christian Wilkoski was very helpful with timing and flexibility. Very much appreciated picking my vehicle up the next day.
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.






Used
2021 Mercedes-Benz E-Class E 450
Vehicle information
Features
Reviews
My service was fantastic You can not do any better!
My service was fantastic You can not do any better! Very satisfied will always come here
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.
There are 4 matching cars close to your year range.






Used
2023 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2023 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
Features



Mercedes-Benz Certified
2023 Mercedes-Benz E-Class
Vehicle information
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About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)

How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $35,463, with pricing starting at $21,726.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
Style | |
---|---|
E 350 RWD Sedan | E 350 4MATIC Sedan |
Inventory price | |
Starting at $54,250 | Starting at $56,750 |
Combined MPG | |
25 | 25 |
Engine | |
255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
Style | |||||
---|---|---|---|---|---|
E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
Inventory price | |||||
Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
Combined MPG | |||||
25 | 24 | 25 | 26 | 26 | 25 |
Engine | |||||
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz E-Class
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
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