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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class
for sale
near
Mission Bend, TX
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
Thank you Hilary for helping us buy our bmw X3 this was
Thank you Hilary for helping us buy our bmw X3 this was the best dealership ever he was really understanding about us trying to buy a new bmw X3 thank Hilary of you are looking for a car at echo ask for Hillary thanks Hillary keep up the good work
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
Service is the best around and they always go above and
Service is the best around and they always go above and beyond to help me out! Fidel, Nick and David Tyson are awesome! Highly recommend BMWCL for all of you BMW service needs.
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.






Used
2021 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
Features
Reviews
Nice cars, really cool store, Austin Sharpe really knows
Nice cars, really cool store, Austin Sharpe really knows the cars. CPO Volvo has a lifetime powertrain warranty which was nice. Thank you for a good car Grubbs.
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.






Used
2021 Mercedes-Benz E-Class
Vehicle information
Features
Reviews
Bought used f 250 truck
Great service, took care of me totally, had the truck transferred from another Car Max, they followed it through the purchase and the drive out from the facility.
This car is why you buy a Mercedes-Benz.
I'm replacing a 17 y/o E-320 that I loved. I am now infatuated with the New 2021 E-450 4 matic it just so happens to be the Motor Trend car of the year. Very nice exterior styling. Fantastic interior. all the latest technology and a great interior. The strait V-6 with turbo is smooth as silk. The optional Air Body control suspension makes for a fantastic smooth ride.






Mercedes-Benz Certified
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
The quality and care that the service department gives me
The quality and care that the service department gives me is consistently exceptional. Our service advisor takes care to keep me informed through the whole repair process.
Love my Car
The vehicle meets all of my needs. I special ordered the vehicle with the color and leather interior I prefer. It arrived exactly the way I wanted.






Used
2021 Mercedes-Benz E-Class E 450
Vehicle information
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Reviews
Got my new 760I from BMW west Houston and really happy
Got my new 760I from BMW west Houston and really happy about the experience, actually this time we barely spend time at the dealer, Tommy Luk is awesome, bought multiple cars from him and always getting a great deal, every time we are due to start a new lease or buy a new car Tommy is our first call, he goes above and beyond for us, and special mention to Camilo he always makes sure that by the time we leave we know all the features of the car not just the basic ones.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
Toyota Corolla
This has been the second best experience on buying a new car from Alex Wier. He took his time and was so very patient with us. I will continue to buy my next Toyota vehicle from Joe Myers Toyota. Usually it feels creepy walking into a dealership, but this place was very comfortable.






Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
I love my new C300!
Pete Sanchez is the. Thank you for your help w the purchase of my new C300 Mercedes! I love it and thank you for the pics!

Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
Just perfect as always.
Just perfect as always. Surender it?s the best!!! I appreciated. It was always a pleasure to buy a car at that dealership.Thank you!
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2023 Mercedes-Benz E-Class E 350
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Features
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Mercedes-Benz E-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2026 Mercedes-Benz E-Class | $65,750 | |
2025 Mercedes-Benz E-Class | $53,880 | 7 Good deals |
2014 Mercedes-Benz E-Class | $4,950 | 6 Great deals |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)

How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $36,146, with pricing starting at $21,326.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
Style | |
---|---|
E 350 RWD Sedan | E 350 4MATIC Sedan |
Inventory price | |
Starting at $54,250 | Starting at $56,750 |
Combined MPG | |
25 | 25 |
Engine | |
255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
Style | |||||
---|---|---|---|---|---|
E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
Inventory price | |||||
Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
Combined MPG | |||||
25 | 24 | 25 | 26 | 26 | 25 |
Engine | |||||
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz E-Class
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