Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Mercedes-Benz S-Class sedans
for sale
near
Opa-locka, FL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Mercedes-Benz S-Class S 500 4MATIC
Vehicle information
Features
Reviews
Francisco Esteves always does a great job!
Francisco is and excellent exmaple of someone dedicated to his work and serving his clients. With care and professionalism. The work is done right the first time and the updates as the car moves along are appreicated. No more is needed to say Excellent
MBZ S-class always 5 ***** vehicle.
MBZ S-class always 5 ***** vehicle. The most luxurious , comfortable, car I ever drove . I highly recommend it . My old Mercedes S-class has 200,000 miles and not a single problem.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
My Experience at Mercedes of Fort Lauderdale
I live in Pompano Beach which has a Mercedes Dealership and Service Center but I choose to drive a half hour to Mercedes of Fort Lauderdale because of their rich personalized service experience. Our service manager Torey Williams is extraordinary and exceptional. He listens intensely to ensure he addresses all details. Mercedes of Fort Lauderdale values and appreciates us as clients. Check it out?you won?t be disappointed, you will be delighted.
A Wonderful Overall Experience
I just picked up my S580 Lux-Line in Emerald Green over Sienna Brown, and I am absolutely thrilled with the purchase. I have owned five S-Class models since 2010, including this new one, and I can say this is the best iteration yet from an overall perspective. While I still think the W222 was the best-looking (especially my 2019 S560 with the refreshed look and AMG pack), this new one does not disappoint at all. The Emerald Green is stunning in the sunlight, my favorite color yet. And the interior is on another level from a luxury and tech standpoint. I loved the interiors of all the S-Class models I've owned, but this current one is my favorite. The seats are super supportive, and the vast amount of tech is amazing. The new infotainment screen takes time to learn and get used to, but I feel the "Hey, Mercedes" function makes doing small things like putting in a Navigation request easier than going through the main screen. From a driving perspective, the ride is the best yet, just like gliding on a cloud. I've been lucky to have driven Bentley's and Rolls-Royce's in my lifetime, and this ride is as close as I've seen the S-Class come to being even with those vehicles on this front. And, the V8 is plenty punchy when needed, so it can be a fun vehicle to take on windy roads if you so desire. Overall, a wonderful vehicle and a bargain when you compare it to the other super-luxury vehicles on sale. I'm looking forward to the next few years of owning such an awesome car.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Great Experience With Javier
Had an excellent experience buying a pre-owned Bentley. Car was exactly as represented. Bought based on photos and largely over the phone. When we got there, could not have been happier with the quality. There were some concerns originally based a few of the pictures, but Javier patiently hung in there and put us at ease. So glad he did! Ecstatic with the purchase. And financing was great and smooth too!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Charlie and the rest of the team were incredible!
Charlie and the rest of the team were incredible! We will definitely come back for any future cars






Used
2022 Mercedes-Benz S-Class S 500 4MATIC
Vehicle information
Features
Reviews
Mike facilitated financing on a car I wanted to sell.
Mike facilitated financing on a car I wanted to sell. Then transferred the trade in credits on my new vehicle which saved me a lot of money. Thank you Mike. I wish you the best on your endeavors






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
This is my second purchase from Hgreg.
This is my second purchase from Hgreg. Both cars were fantastic. Leo was great to deal with






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Coast to Coast is a very professional dealership.
Coast to Coast is a very professional dealership. I was treated with respect and professionalism from the time I walked through the door. Dylan and Omar took good care of us from the time we looked at the car to taking a test drive and writing up a sales deal. Coast to Coast carries quality inventory, and back it up. Thank you.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Francisco Esteves always does a great job!
Francisco is and excellent exmaple of someone dedicated to his work and serving his clients. With care and professionalism. The work is done right the first time and the updates as the car moves along are appreicated. No more is needed to say Excellent






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Great Experience
Purchased a used vehicle through Ed Molko. Ed was honest, professional, and efficient in guiding me through a remote purchase. Prestige delivered the vehicle on time and the car was exactly as described. I would not hesitate to purchase from Ed and Prestige again.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Mercedes S-580
Knowledgeable, professional staff at every level from sales to closing to service maintenance at Mercedes of Pompano, Florida






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
I recently bought my stunning EQS 450+ from Mercedes-Benz
I recently bought my stunning EQS 450+ from Mercedes-Benz of Coconut Creek, and I couldn?t be more pleased with the entire experience! From the moment I stepped in, the dealership had a welcoming and professional vibe, but it was David G. who really made my visit memorable. His expertise, patience, and genuine enthusiasm turned the entire process into a smooth and enjoyable one. Although there was a minor hiccup with Ariel from the financial department, who didn?t seem quite as excited to share in my excitement, it didn?t take away from the overall fantastic experience. David?s exceptional service truly outweighed any small bumps in the road. A big thank you to David for making my car-buying journey so unforgettable. I absolutely love my new EQS 450+, and I?ll be recommending Mercedes-Benz of Coconut Creek to others because of the excellent service I received!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Good cars and honest people.
Good cars and honest people. David was very helpful and they didn't have a problem with my mechanic checking out the car before I purchased. I will do business with #1 Auto Sales again.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Extremely Satisfied
To begin with my daughter experienced, her sale associate Was Mr Joe he was very helpful and had a lot of patience with her during the process of her getting her dream vehicle , he never fail to answer any of her questions , he was always available and ready to help her with anything she needed in order for her to purchase her dream vehicle .the staff were very nice the environment was very clean and you just felt comfortable and welcomed by everyone there .From my daughter and I would say Mr Joe is the best and we thank you for the help .






Used
2022 Mercedes-Benz S-Class S 500 4MATIC
Vehicle information
Features
Reviews
A dream come true
I had an Amazing experience with Jorge Martinez at the dealership. I would never thought that I would drive a Mercedes but Jorge made incredible easy. We drove different cars and he was super professional and got me all the details. He help me find the right number and the finance process was a breeze. This is a Dream come true not only because I have an amazing Mercedes but the Fact that is Electric makes all the difference in the world. Highly recommend this dealer and please look for Jorge for all your needs.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
This a great place to buy a car.
This a great place to buy a car. Joe treated my wife and I with care and respect. No pressure sale and kept us in the loop throughout our purchase, would definitely buy here again.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Once again Mercedes Benz of Pompano and Koby our service
Once again Mercedes Benz of Pompano and Koby our service advisor did a great job. The car was in and out in a day. No hassles. My wife and I are happy customers.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 500 4MATIC
Vehicle information
Features
Reviews
Service
Had car ready before expected and service consultant when out of his way to get me a loaner picking car up was very fast and efficient
-
Prev - 1
- 2
-
Next
Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $119,477 | 1 Good deal |
About the 2022 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2022 Mercedes-Benz S-Class cost?
The 2022 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 S-Class is $76,470, with pricing starting at $48,359.
What is the MPG of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class offers up to 21 MPG in city driving and 30 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
Is the 2022 Mercedes-Benz S-Class reliable?
The 2022 Mercedes-Benz S-Class has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 S-Class owners.
Is the 2022 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
50% of drivers recommend this car
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $111,100 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $117,700 |
Combined MPG |
19 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Mercedes-Benz S-Class
Compare the 2022 Mercedes-Benz S-Class
2022 Mercedes-Benz S-Class Sedans by city
-
2022 Mercedes-Benz S-Class Sedans in Westview, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Miami Gardens, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Pinewood, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in West Little River, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Golden Glades, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Hialeah, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Miami Lakes, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Country Club, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Biscayne Park, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in El Portal, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in Miami Shores, FL
2 Great Deals out of 25 listings starting at $59,900
-
2022 Mercedes-Benz S-Class Sedans in North Miami, FL
2 Great Deals out of 25 listings starting at $59,900
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}