Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Mercedes-Benz S-Class sedans
for sale
near
Willowbrook, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Great Service Department
The service manager was very helpful. I dropped off at 10 am and my Lamborghini was ready for pick up 3 pm the same day.
MBZ S-class always 5 ***** vehicle.
MBZ S-class always 5 ***** vehicle. The most luxurious , comfortable, car I ever drove . I highly recommend it . My old Mercedes S-class has 200,000 miles and not a single problem.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Great experience as soon as I walk in every one was
Great experience as soon as I walk in every one was friendly and helpful. I recommend this dealership 100%
A Wonderful Overall Experience
I just picked up my S580 Lux-Line in Emerald Green over Sienna Brown, and I am absolutely thrilled with the purchase. I have owned five S-Class models since 2010, including this new one, and I can say this is the best iteration yet from an overall perspective. While I still think the W222 was the best-looking (especially my 2019 S560 with the refreshed look and AMG pack), this new one does not disappoint at all. The Emerald Green is stunning in the sunlight, my favorite color yet. And the interior is on another level from a luxury and tech standpoint. I loved the interiors of all the S-Class models I've owned, but this current one is my favorite. The seats are super supportive, and the vast amount of tech is amazing. The new infotainment screen takes time to learn and get used to, but I feel the "Hey, Mercedes" function makes doing small things like putting in a Navigation request easier than going through the main screen. From a driving perspective, the ride is the best yet, just like gliding on a cloud. I've been lucky to have driven Bentley's and Rolls-Royce's in my lifetime, and this ride is as close as I've seen the S-Class come to being even with those vehicles on this front. And, the V8 is plenty punchy when needed, so it can be a fun vehicle to take on windy roads if you so desire. Overall, a wonderful vehicle and a bargain when you compare it to the other super-luxury vehicles on sale. I'm looking forward to the next few years of owning such an awesome car.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Sales rep (Kenn) and GM (Bradley) were awesome to work
Sales rep (Kenn) and GM (Bradley) were awesome to work with. Just the kind of buying experience everyone is looking for. Highly recommended!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Armin was amazing to work with, went above and beyond in
Armin was amazing to work with, went above and beyond in more ways than one, to ensure we had a pleasant experience. We brought the car while in Colorado, having it shipped. Was exactly we expected. Highly recommend!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Owner of the company reached out to me and take care off
Owner of the company reached out to me and take care off all issues even it was after work hours. Good customer service.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Steve was an excellent sales rep.
Steve was an excellent sales rep. Ultimo has a great stable of cars to select from. Steve went out of his way to help me with my trade in, new summer wheels & tires and answered all of my questions accurately.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I was skeptical about purchasing a car from a used car
I was skeptical about purchasing a car from a used car dealer however in having very good experience in purchasing a new BMW from Perillo BMW many years ago the Perillo name provided me some comfort. Perillo Downers Grove delivered upon my expectation’s in purchasing a lightly used BMW 750i






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Had a fantastic experience with Motor Cars of Chicago,
Had a fantastic experience with Motor Cars of Chicago, Seraj “Raj” Abughoush was amazing to work with. He was attentive from start to finish. I am an out of town buyer and Raj worked with me to make sure I was satisfied before and after purchase. He followed up timely and walked the vehicle with me via FaceTime twice. He took me on a drive via FaceTime and even found a chip in the window and had it fixed before delivery. I will definitely buy another vehicle from Motor Cars of Chicago, they have a customer for life. The manager was also highly engaged And customer focused. I highly recommended and customer friendly. Thanks Raj and team.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
The dealership had a great selection of quality used
The dealership had a great selection of quality used cars, all well-maintained and reasonably priced. I appreciated their transparency and honesty throughout the process, including providing detailed vehicle history reports. The financing process was also seamless, offering several options and explaining everything clearly. I left feeling confident and satisfied with my purchase. Overall, I highly recommend Affinity Auto Sales to anyone looking for a reliable used car and a pleasant buying experience. Thank you to the entire team for making this such a positive experience!



Mercedes-Benz Certified
2022 Mercedes-Benz S-Class
Vehicle information






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Let start off my saying these bugs are great.
Let start off my saying these bugs are great. Made sure I was comfortable with what I was buying and made the process very easy and simple.



Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Best dealer
Great team to work with, and very friendly very quick service. Great selection of cars too. Will definitely refer them to my friends. Very nice place






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Very responsive and got back to me promptly and checked
Very responsive and got back to me promptly and checked in after the initial email.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Very responsive.
Very responsive. Very knowledgeable about the Tesla Model S Plaid. Friendly and great communications from the first phone call to the last.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Chris and Matt are all world!
Chris and Matt are all world! Love my car and our entire experience buying from them. Very responsive and dependable. Knowledgeable as well. Joey






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I highly recommend Chicago motor cars.
I highly recommend Chicago motor cars. I have purchased a few vehicles from them. They get it done fast and right. No fluff
Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Marky mark
I came in here looking for purchase a new Toyota rav 4. The associate there name mark was super helpful and patient. You could tell he enjoyed his job, even though I i didn’t purchase a vehicle when I come back I want marky mark(nickname i gave him yeah so what)






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Service was amazing!
Service was amazing! I would say we were in and out within an hour and a half our advisor explained everything to us. We have no complaints.
-
Prev - 1
- 2
-
Next
Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $125,995 | |
2023 Mercedes-Benz S-Class | $63,985 | 6 Good deals |
About the 2022 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2022 Mercedes-Benz S-Class cost?
The 2022 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 S-Class is $72,185, with pricing starting at $48,426.
What is the MPG of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class offers up to 21 MPG in city driving and 30 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
Is the 2022 Mercedes-Benz S-Class reliable?
The 2022 Mercedes-Benz S-Class has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 S-Class owners.
Is the 2022 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
50% of drivers recommend this car
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $111,100 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $117,700 |
Combined MPG |
19 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Mercedes-Benz S-Class
Compare the 2022 Mercedes-Benz S-Class
2022 Mercedes-Benz S-Class Sedans by city
-
2022 Mercedes-Benz S-Class Sedans in Burr Ridge, IL
6 Great Deals out of 27 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Darien, IL
7 Great Deals out of 29 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Clarendon Hills, IL
7 Great Deals out of 28 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Indian Head Park, IL
7 Great Deals out of 29 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Westmont, IL
7 Great Deals out of 28 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Hinsdale, IL
7 Great Deals out of 29 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Western Springs, IL
7 Great Deals out of 29 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Countryside, IL
7 Great Deals out of 29 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Willow Springs, IL
6 Great Deals out of 27 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Downers Grove, IL
7 Great Deals out of 28 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in Hodgkins, IL
6 Great Deals out of 27 listings starting at $59,991
-
2022 Mercedes-Benz S-Class Sedans in La Grange, IL
7 Great Deals out of 29 listings starting at $59,991
Mercedes-Benz S-Class trims
-
Mercedes-Benz S-Class 2022 S 580 4MATIC
5 Great Deals out of 24 listings starting at $59,991
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}