Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2021 GMC Sierra 2500 trucks
for sale
near
Wilmington, MA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






GMC Certified
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Joe DuCharme
When waiting repairs. It?s a very comfortable place to wait. 2 different waiting area?s both with tv?s. Coffee, water and soda always available!
Beautiful truck
I love my 2021 GMC Denali 2500HD. I have gotten more complements on this truck than any other vehicle that I have owned. I get great highway fuel milage average 19-26mpg,which is great for a heavy duty truck!






Vehicle information
Features
Reviews
I bought my infiniti through DC motors.
I bought my infiniti through DC motors. Chris has been down to earth and great to deal with. I will certainly go back.
Best truck I ever owned
Love my GMC. Owned a Chevy and this absolutely beats it hands down. Never had any issues. Inside is very comfortable and can't imagine driving anything else






GMC Certified
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Very satisfying with the whole process.
Very satisfying with the whole process. I have purchased many vehicles and this one went perfectly. I would definitely recommend this dealership. Thank you greater lol GMC
GMC 2500 HD AT4
This is the first diesel I have owned. The power is amazing and I really like the room inside the cab. This truck is a beast... Love it!






Vehicle information
Features
Reviews
Just purchased a 2025 Honda accord with Driss my
Just purchased a 2025 Honda accord with Driss my purchasing experience was amazing I also want to give a big thank you to they’re finance manager Josh who went above and beyond in getting me the car in a timely manner he’s very efficient with his work and his work ethic is something to not go unnoticed working with him was such a pleasure!
Never had one. Always wanted one and love it.
I love my Denali. Beautiful truck inside out. When I drive down the road all heads turn. I couldn't have made a better choice. That's Cortez for you good service.
There are 10 matching cars close to your year range.






Vehicle information
Features






Used
2022 GMC Sierra 2500 Denali
Vehicle information
Features






GMC Certified
2023 GMC Sierra 2500 Denali
Vehicle information
Features






Used
2020 GMC Sierra 2500 SLT
Vehicle information
Features






Used
2023 GMC Sierra 2500 Denali
Vehicle information
Features






Used
2023 GMC Sierra 2500 Denali
Vehicle information
Features
Used
2019 GMC Sierra 2500 DOUBLE CAB 158.1
Vehicle information
Features

Used
2020 GMC Sierra 2500 Base
Vehicle information
Features

Used
2022 GMC Sierra 2500 SLE
Vehicle information
Features

Used
2022 GMC Sierra 2500 AT4
Vehicle information
Features
-
Prev - 1
-
Next
GMC Sierra 2500 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 GMC Sierra 2500 | $50,292 | 1 Good deal |
2024 GMC Sierra 2500 | $48,700 | 12 Good deals |
About the 2021 GMC Sierra 2500
Base shown (base trim).
- Seating
- 3
- Door count
- 2
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 0
- Transmission
- 6-Speed A/T
- Engine
- 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel)

How much does the 2021 GMC Sierra 2500 cost?
The 2021 GMC Sierra 2500 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 Sierra 2500 is $53,801, with pricing starting at $30,496.
What are some similar vehicles and competitors of the 2021 GMC Sierra 2500?
The 2021 GMC Sierra 2500 compares to and/or competes against the following vehicles:
Is the 2021 GMC Sierra 2500 reliable?
The 2021 GMC Sierra 2500 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 Sierra 2500 owners.
Is the 2021 GMC Sierra 2500 a good truck?
Below are the Cars.com consumer ratings for the 2021 GMC Sierra 2500.
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
75% of drivers recommend this car
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
AT4 (2 styles)
Style | |
---|---|
4WD Crew Cab 172" AT4 | 4WD Crew Cab 159" AT4 |
Inventory price | |
Starting at $59,300 | Starting at $59,100 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Base (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
4WD Crew Cab 159" | 2WD Crew Cab 172" | 4WD Crew Cab 172" | 2WD Crew Cab 159" | 2WD Double Cab 162" | 4WD Double Cab 162" | 4WD Double Cab 149" | 2WD Double Cab 149" | 2WD Reg Cab 142" | 4WD Reg Cab 142" |
Inventory price | |||||||||
Starting at $43,400 | Starting at $40,800 | Starting at $43,600 | Starting at $40,600 | Starting at $39,000 | Starting at $41,800 | Starting at $41,600 | Starting at $38,800 | Starting at $36,200 | Starting at $39,000 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Denali (2 styles)
Style | |
---|---|
4WD Crew Cab 172" Denali | 4WD Crew Cab 159" Denali |
Inventory price | |
Starting at $65,700 | Starting at $65,500 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLE (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
2WD Crew Cab 172" SLE | 4WD Crew Cab 159" SLE | 2WD Crew Cab 159" SLE | 4WD Crew Cab 172" SLE | 2WD Double Cab 162" SLE | 2WD Double Cab 149" SLE | 4WD Double Cab 149" SLE | 4WD Double Cab 162" SLE | 4WD Reg Cab 142" SLE | 2WD Reg Cab 142" SLE |
Inventory price | |||||||||
Starting at $45,600 | Starting at $48,200 | Starting at $45,400 | Starting at $48,400 | Starting at $43,800 | Starting at $43,600 | Starting at $46,400 | Starting at $46,600 | Starting at $44,400 | Starting at $41,600 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLT (8 styles)
Style | |||||||
---|---|---|---|---|---|---|---|
4WD Double Cab 162" SLT | 2WD Double Cab 149" SLT | 2WD Double Cab 162" SLT | 4WD Double Cab 149" SLT | 4WD Crew Cab 159" SLT | 2WD Crew Cab 159" SLT | 2WD Crew Cab 172" SLT | 4WD Crew Cab 172" SLT |
Inventory price | |||||||
Starting at $54,600 | Starting at $51,600 | Starting at $51,800 | Starting at $54,400 | Starting at $56,200 | Starting at $53,400 | Starting at $53,600 | Starting at $56,400 |
Combined MPG | |||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 GMC Sierra 2500
Compare the 2021 GMC Sierra 2500
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}