2026
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
1999
1998
1997
1996
1995
1994
1993
1992
GMC Sierra 2500
Shop the 2021 GMC Sierra 2500 near you
-
$50,977
Used 2021 GMC Sierra 2500 21 mi away
-
$49,077
Used 2021 GMC Sierra 2500 27 mi away
-
$51,912
Used 2021 GMC Sierra 2500 30 mi away
-
$63,590
Used 2021 GMC Sierra 2500 34 mi away
-
$59,407
Used 2021 GMC Sierra 2500 42 mi away
-
$62,267
Used 2021 GMC Sierra 2500 46 mi away
-
$53,999
Used 2021 GMC Sierra 2500 52 mi away
-
$55,195
Used 2021 GMC Sierra 2500 71 mi away
-
$80,000
Used 2021 GMC Sierra 2500 76 mi away
-
$35,577
Used 2021 GMC Sierra 2500 77 mi away
Available trims
-
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs -
Shop this trim See all specs
The good & the bad
Factory warranties
- Basic
- 3 years / 36,000 miles
- Corrosion
- 3 years / 36,000 miles
- Powertrain
- 5 years / 60,000 miles
- Roadside Assistance
- 5 years / 60,000 miles
Compare similar vehicles
-
2021GMC Sierra 2500Starts at$36,200
- Seat capacity
- 3
- Engine
- Gas V8
- Drivetrain
- Rear-wheel drive
- Payload Capacity
- 3,976 lbs
- Towing Capacity
- 14,500 lbs
Compare -
2020GMC Sierra 3500Starts at$37,000
- Seat capacity
- 2
- Engine
- Gas V8
- Drivetrain
- Rear-wheel drive
- Payload Capacity
- 4,534 lbs
- Towing Capacity
- 20,000 lbs
Compare -
2024Chevrolet Silverado 2500Starts at$44,400
- Seat capacity
- 3
- Engine
- Gas V8
- Drivetrain
- Rear-wheel drive
- Payload Capacity
- 4,055 lbs
- Towing Capacity
- 20,000 lbs
Compare -
2022GMC Sierra 2500Starts at$40,200
- Seat capacity
- 3
- Engine
- Gas V8
- Drivetrain
- Rear-wheel drive
- Payload Capacity
- 4,109 lbs
- Towing Capacity
- 18,500 lbs
Compare
Most recent
-
Bought the vehicle with 97,000 miles on it.
Bought the vehicle with 97,000 miles on it. within 10,000 miles had to replace injector number three. First winter all three heating element’s went out. Took it down to have it serviced and the tech found a leak coming from the transmission upon further inspection. The seal before the torque converter was already bad and leaking- Purchased a Used car
- Used for Commuting
- Does not recommend this car
-
This thing has been a nightmare since we bought it.
This thing has been a nightmare since we bought it. We purchased it used in 24 with 100k miles. A few months later it blew a head gasket and had to have a new engine put in. Since then it's been chasing down intermittent, random check engine codes and losing coolant to which we can't find the source of. The multipro tailgate- Purchased a Used car
- Used for Transporting family
- Does not recommend this car
-
Beautiful truck
I love my 2021 GMC Denali 2500HD. I have gotten more complements on this truck than any other vehicle that I have owned. I get great highway fuel milage average 19-26mpg,which is great for a heavy duty truck!- Purchased a New car
- Used for Having fun
- Does recommend this car
-
Best truck I ever owned
Love my GMC. Owned a Chevy and this absolutely beats it hands down. Never had any issues. Inside is very comfortable and can't imagine driving anything else- Purchased a Used car
- Used for Commuting
- Does recommend this car
-
Unreliable mechanical and technical nightmare!
First GMC, last GMC. Buyers, run in the other direction from the 2021 GMC Sierra 2500HD Denali, or live with daily, expensive regret! This is the worst and most unreliable vehicle I have ever purchased (new), and I have had many new and used. Steer clear of this year, make, and model! Expect mechanical failures, issues and annoyances- Purchased a New car
- Used for Commuting
- Does not recommend this car
-
Consider with caution
I have had my 2021 Sierra 2500HD Diesel Denali for less than a year now. I bought it because we are fulltime RV'ers hauling a 35' 5th wheel. The power is fantastic and feels like we're hauling nothing, even in the NC mountains. The looks inside and out are great as well. I love this truck...WHEN IT WORKS. I have had to have- Purchased a New car
- Used for Commuting
- Does not recommend this car
-
GMC 2500 HD AT4
This is the first diesel I have owned. The power is amazing and I really like the room inside the cab. This truck is a beast... Love it!- Purchased a New car
- Used for Towing
- Does recommend this car
-
Never had one. Always wanted one and love it.
I love my Denali. Beautiful truck inside out. When I drive down the road all heads turn. I couldn't have made a better choice. That's Cortez for you good service.- Purchased a Used car
- Used for Commuting
- Does recommend this car
-
Early to tell truck has less than 100 miles
Truck was bought specifically to our travel trailer. We have to wait for 1000 break in before we can tow the trailer. So far the truck is very quiet, smooth running, & comfortable to drive. We were pleasantly surprised at how much interior storage space is available. Having the bed steps before rear tires and in the bumper sides- Purchased a New car
- Used for Towing
- Does recommend this car
-
Great Truck
First diesel, excellent fuel mileage, much more comfortable and roomy compared to my previous 2016 GMC 2500 New mirror location does pose issue with seeing people or cars (blind spot) Overall extremely pleased- Purchased a New car
- Used for Towing
- Does recommend this car
-
MY second GMC 2500 HD and it won't be my last.
I just upgraded from my 2016 GMC 2500 to a new 2021 GMC 2500. I really liked my 2016 and had decided it was the best truck I had owned in 40 plus years of owning and driving pickup trucks. I just picked up the 2021 and it is a vast improvement in almost everyway over the 2016. The technology, design and ride of the truck- Purchased a New car
- Used for Towing
- Does recommend this car
-
Incredible beast of a truck!!!
2021 GMC 2500 Denali is an exceptional truck. It’s ride is beyond any truck expectations. The auto operating running boards have turned out to be great for getting in and out of this beast of a truck. I got this truck to haul my 5th wheel trailer and it pulls the trailer like it’s not even there. Styling in and out is- Purchased a New car
- Used for Towing
- Does recommend this car
Latest Sierra 2500 stories
GMC dealers near you
FAQ
What trim levels are available for the 2021 GMC Sierra 2500?
The 2021 GMC Sierra 2500 is available in 5 trim levels:
- (10 styles)
- AT4 (2 styles)
- Denali (2 styles)
- SLE (10 styles)
- SLT (8 styles)
What are some similar vehicles and competitors of the 2021 GMC Sierra 2500?
The 2021 GMC Sierra 2500 compares to and/or competes against the following vehicles:
Is the 2021 GMC Sierra 2500 reliable?
The 2021 GMC Sierra 2500 has an average reliability rating of 4.0 out of 5 according to cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 GMC Sierra 2500 owners.
Is the 2021 GMC Sierra 2500 a good Truck?
Below are the cars.com consumers ratings for the 2021 GMC Sierra 2500. 75.9% of drivers recommend this vehicle.
- Comfort: 4.7
- Interior: 4.6
- Performance: 4.3
- Value: 3.9
- Exterior: 4.6
- Reliability: 4.0
GMC Sierra 2500 history
-
2026 GMC Sierra 2500 -
2025 GMC Sierra 2500 -
2024 GMC Sierra 2500 -
2023 GMC Sierra 2500 -
2022 GMC Sierra 2500 -
2021 GMC Sierra 2500 -
2020 GMC Sierra 2500 -
2019 GMC Sierra 2500
-
2018 GMC Sierra 2500 -
2017 GMC Sierra 2500 -
2016 GMC Sierra 2500 -
2015 GMC Sierra 2500 -
2014 GMC Sierra 2500 -
2013 GMC Sierra 2500 -
2012 GMC Sierra 2500 -
2011 GMC Sierra 2500 -
2010 GMC Sierra 2500 -
2009 GMC Sierra 2500 -
2008 GMC Sierra 2500 -
2007 GMC Sierra 2500 -
2006 GMC Sierra 2500 -
2005 GMC Sierra 2500 -
2004 GMC Sierra 2500 -
2003 GMC Sierra 2500 -
2002 GMC Sierra 2500 -
2001 GMC Sierra 2500 -
2000 GMC Sierra 2500 -
1999 GMC Sierra 2500 -
1998 GMC Sierra 2500 -
1997 GMC Sierra 2500 -
1996 GMC Sierra 2500 -
1995 GMC Sierra 2500 -
1994 GMC Sierra 2500 -
1993 GMC Sierra 2500 -
1992 GMC Sierra 2500