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Used 2021 Lexus RX 350 for sale near Orangetree, FL

Filters 5 Year Trim Model Price & payment Make Mileage Body style Ext. color All filters
9 matches 30 miles from 34120
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Est. $400 /mo*
Down Payment
$0
Net trade-in value
$0
Months
72
APR
7.0%
Sales tax
0.0%

Vehicle information

Ext. color: Pearl
Int. color: Birch
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: L251084A
VIN: 2T2HZMAAXMC204447

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Navigation System, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats

Reviews

Germain Lexus of Naples review

Professional but very busy.

Professional but very busy. I trust them they have always done great job, O only drive lexus SUV great long term vehicles thst never breakdown.

2021 Lexus RX 350 Base review

RX is the Best !

This 2021 RX is a great vehicle, everything about the RX is high quality, quiet, quick, smooth, well built. Only complaint is cabin is built so tight that I farted in car at airport parking lot. Came back two weeks later from a trip overseas and it still stunk inside.

Vehicle information

Ext. color: Eminent White Pearl
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: MC192094
VIN: 2T2HZMAA7MC192094

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

Tamiami Ford Inc review

Michael Carbonia was a pleasure to work with.

Michael Carbonia was a pleasure to work with. He was patient and fun to deal with. I would recommend him anytime. Thank you . Kay Mrachek

2021 Lexus RX 350 Base review

Love my New Lexus RX 350!

I love my new RX350! I love the Atomic silver and the styling. The technology is not real user friendly, but it can do a lot! It’s nice to drive, since it is so quiet and smooth riding. I paid cash but still hand to pay full retail price for the Certified 2021 with low miles. The dealership in Tulsa was great, though.

Vehicle information

Ext. color: Silver
Int. color: Birch
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: L250954A
VIN: 2T2HZMAA0MC204635

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Navigation System, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats

Reviews

Germain Lexus of Naples review

Car clean after service Took two hours for oil change

Car clean after service Took two hours for oil change -inspection-tire rotation Seamed like long time to me

2021 Lexus RX 350 Base review

Lexus RX 350 great car!

This is the 2021 Lexus RX 350 and is my 4th Lexus and I love it! The 2018 was also really great and so was the 2015. I think the price is very good and the value is incredible because either way, either leasing rates are great due to the high residual values, and the buy rates are great because you could sell your car used because they are very much in demand and you get a lot for it. If you hold onto your Lexus, that's another great option, because the Lexus engine is incredible, built to protect the engine and last a very long time! I have not had any issues with any of my Lexus ((unlike other car brands -I have had issues with other cars warning lights, electrical, rotors, struts, sensor issues, and faulty parts, and check engine light and other quirks etc!!!)) I totally recommend Lexus -very reliable and no problems! Servicing is always reasonable too!

Vehicle information

Ext. color: Eminent White Pearl
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: L251095A
VIN: 2T2HZMAA2MC186879

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio
Exterior: Alloy Wheels
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats

Reviews

Germain Lexus of Naples review

Had a tire that was road damaged and not repairable.

Had a tire that was road damaged and not repairable. it was covered under a two year road hazard warranty at Lexus. Went to Germain Lexus in Florida. Lee Glesmer was our service rep. He did a fantastic job in telling us when replacement was approved and step-by-step follow-up of the service status. Lee is customer-focused and professional. excellent service experience!

2021 Lexus RX 350 Base review

My choice in ultimate Luxury.

I compared the Lexus Luxury trim model feature for feature with 3 other top Luxury cars. The Lexus offered me much more. On top of that is it’s phenomenal reliability rating. I believe its the smoothest, quietest, driving car of the brands, too!

Vehicle information

Ext. color: Celestial GF
Int. color: F SPORT Black w/Blue
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: MC200589
VIN: 2T2SZMAA2MC200589

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Memory Seat

Reviews

Tamiami Hyundai review

Excellent dealership that believes in creating long term

Excellent dealership that believes in creating long term customer relationships - they took great care of me. Greg Abraham, GM; Carlos Caraballo, Gen.Sales Mngr, and Vinnie Incorvaia, Sales Mngr. - My partner has been leasing and buying cars there for 14 years, so I followed suit. I bought a lovely E400, which was totalled by a truck after only 4 months. I went back and they had another E400 - this time a convertable. I bought the car "as is" - however, there were some problems and one in particular I felt compelled to reach out about. They truly didn't have to do anything, however, the paid for the issue, and as well, threw in an extra that was big and totally unexpected. I cannot say enough - I think everyone knows how tough buying a car is, especially pre-owned and how the follow-up afterwards can be so challenging. I generally would have sucked it up and just not bothered. Vinnie even called me from home after work and the GM saw me immediately within 24 hours. They have a customer for life with me. signed: David Magsumbol

2021 Lexus RX 350 F SPORT Appearance review

Most Comfortable car I have owned

The car met all my needs. It has a good exterior style. It has very smooth running. The electronics are top class. It is user friendly without making it too complicated to operate.

Vehicle information

Ext. color: Matador Red Mica
Int. color: Parchment
Drivetrain: All-wheel Drive
MPG: 19-26
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: CH052917
VIN: JTJHZMDA0M2052917

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment: Bluetooth®, CD Player, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Stability Control
Seating: Leather Seats

Reviews

Hyundai of Fort Myers review

Great Service!

Edgar sold us our 2022 Hyundai TusconSEL. Even after the sale, he has bent over backwards to be friendly, kind, and efficient. I wish all car sales personnel had him as a role model! Thank you, Edgar!

Vehicle information

Ext. color: Moonbeam Beige Metallic
Int. color: Parchment
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: L251089B
VIN: 2T2HZMAA1MC182564

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats

Reviews

Germain Lexus of Naples review

Setting up the service session was easy, the check in

Setting up the service session was easy, the check in process was quick, Daniella met me in the wait area within minutes of my arrival and explained what would be done and how long it would take, and, when completed, she reviewed everything and escorted me to my waiting car. As usual, the Germain team did a wonderful job from start to finish!

Vehicle information

Ext. color: Caviar
Int. color: Glazed Caramel
Drivetrain: All-wheel Drive
MPG: 19-26
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: MC289599
VIN: 2T2HZMDA2MC289599

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

Tamiami Hyundai review

We just leased a 2025 Kona SUV.

We just leased a 2025 Kona SUV. We worked with Dean in Sales who was terrific and Remi in Finance who was also great. This was THE easiest transaction we have ever completed with a car dealership. This dealership is so well managed. There is no pressure. I would highly recommend Tamiami Hyundai, AND we will surely do business again with them. Thank you, Dean and Remi!

Vehicle information

Ext. color: Eminent White Pearl
Int. color: Parchment
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-speed automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: FG036814A
VIN: 2T2AZMAA8MC211804

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats

Reviews

Fort Myers Genesis review

I had a great experience and the staff was very helpful.

I had a great experience and the staff was very helpful. This is a great dealership that treats the customer like family

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Lexus RX 350 prices by year

Model year Prices from Deals
2025 Lexus RX 350 $51,659 1 Good deal

About the 2021 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus RX 350
FAQs

How much does the 2021 Lexus RX 350 cost?

The 2021 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 RX 350 is $37,554, with pricing starting at $27,333.

What is the MPG of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus RX 350 reliable?

The 2021 Lexus RX 350 has an average reliability rating of 4.8 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 RX 350 owners.

Is the 2021 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2021 Lexus RX 350.

(63 reviews)
Rating breakdown (out of 5):
  • Comfort 4.7
  • Interior 4.7
  • Performance 4.7
  • Value 4.6
  • Exterior 4.6
  • Reliability 4.8
Ratings (63 reviews)

88% of drivers recommend this car

Rating breakdown (out of 5):
  • Comfort 4.7
  • Interior 4.7
  • Performance 4.7
  • Value 4.6
  • Exterior 4.6
  • Reliability 4.8
Trims

RX 350 (2 styles)

Style
RX 350 AWD RX 350 FWD
Inventory price
Starting at $46,620 Starting at $45,220
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $48,700 Starting at $50,100
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling AWD RX 350 F SPORT Handling FWD
Inventory price
Starting at $52,500 Starting at $51,100
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.

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