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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2022 Lexus RX 350
for sale
near
Lawrence, MA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Worked with Wayne and Brian.
Worked with Wayne and Brian. They were great. They were really busy when I came in on the weekend, but they worked with me around my work schedule during the week to get everything done. Love my Audi 2018 SQ5 that I bought.
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own






Vehicle information
Features
Reviews
Dennis was as usual great advisor.
Dennis was as usual great advisor. My car is 9 years old which I purchased from Ira Lexus and always service every year. They always do an excellent.
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
We went to Lexus of Watertown this past weekend to test
We went to Lexus of Watertown this past weekend to test drive a car we were contemplating and left with a deal! We met with John Barstow and had a great experience. He was patient, incredibly knowledgeable and friendly (especially with our 8 year-old son!). We had a no-pressure experience as he guided us through all the different models and features. We were impressed by how attentive he was, offering us options and ensuring we had all the necessary information to make a decision. The entire purchasing process was efficient, and we never felt rushed.
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.






Vehicle information
Features
Reviews
Sam was very professional, straight up, and knowledgeable
Sam was very professional, straight up, and knowledgeable about the car. Pleasant to deal with.
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.






Used
2022 Lexus RX 350
Vehicle information
Features
Reviews
AMAZING PLACE TO SHOP!
Hi, my name is Monica, on 11/18/22. I visited the Lexus car dealership at 2600 Fulton st. in Sacramento.I had the most beautiful encounter with Angel the car salesman, Robert in finance, and Brian the store manager. They all demonstrated exceptionally great customer service going above and beyond, making sure that I walk away happy. I pull off in my brand new RX 350 Lexus. Please go and see these guys they're AMAZING!!!!!.... TO GOD BE THE GLORY!!!...






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Ms. Mabie was great! She was very responsive to my
Ms. Mabie was great! She was very responsive to my questions and was quick to get back to me with my requests. Too bad it didn’t work out this time around, but will be keeping her in mind with future car purchases!






Vehicle information
Features
Reviews
Buying Made Easy
Buying a car from Mo was great. I do not like buying cars. I do not like the standard buying script. Thankfully, Mo talked me through the process. Showed me a coupe of vehicles and never pressured me to buy. With his assistance, I was able to make the buying decision that was best for me. In my experience, the prices were more than fair. The team was awesome and they continue to work with you after the sale closes. If you have researched your desired vehicle. Know the prices and what is available. Go see Mo. He probably has the car for you at a great price.






Used
2022 Lexus RX 350 Base
Vehicle information
Features






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Great purchase of my new Lexus at Watertown location.
Great purchase of my new Lexus at Watertown location. Got my car in one day. Alec was awesome as he made the negotiation and transaction smooth. Highly recommend this dealership and Alec. You won't go wrong.






Used
2022 Lexus RX 350 Base
Vehicle information
Features






Vehicle information
Features
Reviews
Jen is an excellent consultant and the mechanic takes
Jen is an excellent consultant and the mechanic takes their time to explain what?s going on with your car to you. They also include a video of your car in the shop and what they found which I find to be extremely helpful.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Bought a Corolla there, had maintenance done today,
Bought a Corolla there, had maintenance done today, wonderful experience! Very fast and professional dealer, great staff. I was done within an hour. Highly recommend this dealer.
Vehicle information
Features
Reviews
Alec was awesome, he was knowledgeable, and easy to work
Alec was awesome, he was knowledgeable, and easy to work with. I will use him and refer others to him.
Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Eliane Lisboa is awesome!
Eliane Lisboa is awesome! She has helped find a great deal and made the process easy. I was in a bit of rush and she was able to help accommodate me and get all the paperwork in the shortest time I have ever seen! I would recommend using her as she has a great of knowledge of the cars and is super friendly to work with. Thank you Elaine!
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Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $55,760 | |
2024 Lexus RX 350 | $50,984 | 8 Good deals |
2015 Lexus RX 350 | $12,999 | 6 Good deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $42,512, with pricing starting at $29,490.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.5
- Interior 4.5
- Performance 3.8
- Value 3.5
- Exterior 4.6
- Reliability 3.9
63% of drivers recommend this car
- Comfort 4.5
- Interior 4.5
- Performance 3.8
- Value 3.5
- Exterior 4.6
- Reliability 3.9
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
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