2022 Lexus RX 350

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2022 Lexus RX 350
2022 Lexus RX 350

Key specs

Base trim shown


Body style


Combined MPG


Seating capacity

192.5” x 67.7”


Front-wheel drive



The good:

  • Overall refinement
  • Cabin materials
  • Seat comfort (base and luxury models)
  • Lack of touch-sensitive buttons
  • Smooth, quiet operation (base model)
  • Easy entry to available third row

The bad:

  • Leather seats not standard
  • Feels heavy in corners
  • Uninspiring braking feel
  • Maddening multimedia controller
  • Stiffly bolstered seats (F Sport)
  • Available third row can’t fit adults

3 trims

Starting msrp listed lowest to highest price

Wondering which trim is right for you?

Our 2022 Lexus RX 350 trim comparison will help you decide.

See also: Find the best SUVs for 2023

Notable features

  • Gas (RX 350) and hybrid (RX 450h) models
  • Three-row L version available
  • Front- or all-wheel drive
  • Touchscreen multimedia system with Android Auto, Apple CarPlay
  • Limited-edition Black Line models available

2022 Lexus RX 350 review: Our expert's take

What Is the 2022 Lexus RX?

The five-seat Lexus RX mid-size luxury SUV is available in gas RX 350 or hybrid RX 450h form. There’s also a performance-oriented F Sport model and a three-row L version that seats up to seven. All use a 3.5-liter V-6 engine, and the RX 450h adds electric motors.

The RX 350 is available with front- or all-wheel drive. The RX 450h is all-wheel-drive only, with an electric motor driving the rear wheels. Competitors include the Cadillac XT5, Acura MDX and Infiniti QX60.

What’s New on the 2022 Lexus RX?

There are no significant changes this year.

What Features in the 2022 Lexus RX Are Most Important?

Standard features include:

  • 18-inch aluminum wheels
  • LED headlights
  • Dual-zone automatic air conditioning
  • 8-inch touchscreen multimedia system
  • Android Auto and Apple CarPlay smartphone connectivity
  • Forward collision warning
  • Automatic emergency braking
  • Lane-keeping assist
  • Adaptive cruise control
  • Blind spot warning with rear cross-traffic alert

Available features include:

  • Panoramic moonroof
  • Hands-free power liftgate
  • Leather-trimmed interior
  • Heated and ventilated front seats
  • Heated second-row seats
  • Heated steering wheel
  • Head-up display
  • Navigation with 12.3-inch touchscreen
  • Mark Levinson premium stereo
  • Rear automatic braking

Should I Buy the 2022 Lexus RX?

Often credited with creating the luxury crossover SUV class, the Lexus RX continues to please buyers looking for refinement, but our editors find it less engaging to drive than some competitors. The Remote Touch multimedia interface remains frustrating, but the inclusion of a touchscreen makes it less of an issue than it was previously. The cramped third row in extended L versions is of dubious usefulness.

Consumer reviews

Rating breakdown (out of 5):
  • Comfort 4.9
  • Interior design 4.9
  • Performance 4.1
  • Value for the money 3.6
  • Exterior styling 5.0
  • Reliability 4.0

Most recent consumer reviews


Great vehicle!

It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.


2022 RX 350 Premium…The last of the finest.

I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.


Best Vehicle Ever!

I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.

See all 8 consumer reviews


New car program benefits
48 months/50,000 miles
72 months/unlimited distance
72 months/70,000 miles
12 months/10,000 miles
Roadside assistance
48 months/unlimited distance

Compare the competitors

See all 2022 Lexus RX 350 articles