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Used
2022 Lexus RX 350
for sale
near
Newport, DE
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 Base
Vehicle information
Features






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Jason Souder, our Salesman made our purchasing process
Jason Souder, our Salesman made our purchasing process easy. From the first phone call to the end of sale, he was courteous, professional, knowledgeable and answered all our questions. My husband being in a wheelchair made things a little more challenging for Jason, but he helped every step of the way even pushing the wheelchair for us. Highly recommend Jason for Salesman
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own






Used
2022 Lexus RX 350 RX 350 F SPORT Handling
Vehicle information
Features
Reviews
Great Consultants at this Dealership
I ended up not purchasing yet from this dealership but during my shopping process for a new Defender, they were awesome. Great consultants, not pushy and really advised me on the best option between new/used, lease/finance.
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
This Dealership worked with me very well for both our
This Dealership worked with me very well for both our mutual benefits. I appreciate that.
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.






Vehicle information
Features
Reviews
Pleased customer
I recently purchased an LC 500 convertible. The entire staff of Wilkie Lexus could not have been more helpful. My many requests were promptly Taken care of. Their patients in bringing me up-to-date with the technology in my new automobile was Never ending.
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.






Vehicle information
Features
Reviews
JJ has made the experience very relaxing and smooth.
JJ has made the experience very relaxing and smooth. Highly recommend. Very knowledgeable and great listener. Very skilled in reading the room!






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
They are great!
They are great! Happy with my purchase! I will recommends this company to any one in search to buy a car!






Vehicle information
Features
Reviews
Used car search
The salesman that contacted me was unable to find the car I wanted. I was very specific with what I wanted. He was very helpful in providing tips as to how I might go about finding the car I want.






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
Have nothing but nice things to say about Mohamed, that
Have nothing but nice things to say about Mohamed, that is why I have dealt with him with my last 3 cars. He is very personable and helpful. Great sales person.
There are 20 matching cars close to your year range.






Certified
2023 Lexus RX 350 F SPORT Handling
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2024 Lexus RX 350 Premium
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2024 Lexus RX 350 Base
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2023 Lexus RX 350 Base
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Certified
2023 Lexus RX 350 F SPORT Handling
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2023 Lexus RX 350 Base
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2023 Lexus RX 350 Luxury
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2023 Lexus RX 350 F SPORT Handling
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Used
2023 Lexus RX 350 Premium
Vehicle information
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Certified
2024 Lexus RX 350 Base
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Certified
2024 Lexus RX 350 Base
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Certified
2024 Lexus RX 350 Base
Vehicle information
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Certified
2024 Lexus RX 350 Base
Vehicle information
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Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $53,693 | |
2024 Lexus RX 350 | $49,899 | 8 Great deals |
2023 Lexus RX 350 | $42,000 | 7 Good deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,129, with pricing starting at $27,377.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
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