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Used 2022 Lexus RX 350 SUVs for sale near Topanga, CA

Filters 6 Year Trim Model Price & payment Make Mileage Body style Ext. color All filters
21 matches 30 miles from 90290
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Est. $400 /mo*
Down Payment
$0
Net trade-in value
$0
Months
72
APR
7.0%
Sales tax
0.0%

Vehicle information

Ext. color: Caviar
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: P50384
VIN: 2T2HZMAAXNC255870

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

2022 Lexus RX 350 Base review

Great Car

This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own

Vehicle information

Ext. color: Nebula Gray Pearl [G
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: NC251592
VIN: 2T2HZMAAXNC251592

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

Land Rover South Bay review

Farzan g

The sales team was amazing . Sabino , Amir They helped find the right car and easy process

2022 Lexus RX 350 Base review

Great vehicle!

It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.

Vehicle information

Ext. color: Gray
Int. color: BROWN
Drivetrain: Rear-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27196742
VIN: 2T2HZMAA6NC251511

Features

Convenience: Heated Steering Wheel, Navigation System, Remote Start
Entertainment: Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats, Memory Seat

Reviews

CarMax Burbank review

S. Champlin

So easy, it left me extremely pleased! I brought two friends with me for "second-third opinions," and they both enjoyed sharing the adventure with me! Very happy with our salesman who explained clearly what each step was in the test drive and through the paperwork.

2022 Lexus RX 350 review

2022 RX 350 Premium…The last of the finest.

I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.

Vehicle information

Ext. color: Grecian Water
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: V4263292-1R
VIN: 2T2YZMAA7NC224169

Features

Convenience: Adaptive Cruise Control, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Blind Spot Monitor, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats, Memory Seat

Reviews

Volkswagen of Downtown LA review

Very happy customer of 7+ years! 5 stars to Moh Z!

Moh Zarrinkamar reached out to me via email and phone to inform me of my lease ending and what amazing deals were available to me. I made an appt. at VW of DTLA and he gave me all my options and guided me throughout the entire process. I was unsure to either purchase my current VW Beetle or lease a new car. With absolutely no pressure Moh gave me figures for several options and I ended up driving away with a new 2018 VW Jetta Wolfsburg edition. I am now paying less than I was with my old lease and driving a brand new car that I love! I definitely know who I will ask for when my lease is up in four years, Moh Zarrinkamar!! Thank you!

2022 Lexus RX 350 F SPORT Handling review

Best Vehicle Ever!

I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.

Vehicle information

Ext. color: Atomic Silver
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: PM2323
VIN: 2T2AZMAA4NC255025

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio
Exterior: Alloy Wheels
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats

Reviews

Shaver Chrysler Dodge Jeep Ram review

I just recently leased a 2015 Grand Cherokee

Our salesmen Was Ben Nagler,I highly recommend him,he was knowledgeable about the brands I was interested in and was not pushy or annoying.

2022 Lexus RX 350 Base review

AMAZING PLACE TO SHOP!

Hi, my name is Monica, on 11/18/22. I visited the Lexus car dealership at 2600 Fulton st. in Sacramento.I had the most beautiful encounter with Angel the car salesman, Robert in finance, and Brian the store manager. They all demonstrated exceptionally great customer service going above and beyond, making sure that I walk away happy. I pull off in my brand new RX 350 Lexus. Please go and see these guys they're AMAZING!!!!!.... TO GOD BE THE GLORY!!!...

Vehicle information

Ext. color: White
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: NC220961P
VIN: 2T2AZMAA1NC220961

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio
Exterior: Alloy Wheels
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats

Vehicle information

Ext. color: Black
Int. color: BLACK
Drivetrain: Rear-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27511628
VIN: 2T2HZMAAXNC254346

Features

Convenience: Heated Steering Wheel, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats, Memory Seat

Reviews

CarMax LAX review

Good for buying cars, not so good for maintaining.

In 2008, my folks bought a new Chrysler Pacifica Limited. The car sales man was great. He knew all about the car and showed us everything about it. The dealership it's self is beautiful and super clean. They also have AWESOME cars inside in which you can sit and mess around in. The overall rating is a 4 BECAUSE, it is so hard to get a hold of these guys to take the car in. We've called 4 or 5 times to only leave messages that have never been responded to, so we are planning on just going there whether they want us to or not!

Vehicle information

Ext. color: Caviar
Int. color: Circuit Red
Drivetrain: All-wheel Drive
MPG: 19-26
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: SS008997SS
VIN: 2T2YZMDA2NC361970

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Memory Seat

Reviews

Lexus Santa Monica review

Ron Holbrook Spoiled Us!

Ron Holbrook had our vehicle ready and waiting for us when we arrived. The whole process went smoothly and didn't take longer than necessary. He definitely raised the bar as far as car shopping experiences go!

Vehicle information

Ext. color: Atomic Silver
Int. color: Parchment
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L7727
VIN: 2T2HZMAA8NC245774

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Memory Seat

Reviews

LA City Cars review

They are a great group of professionals!

They are a great group of professionals! I had the best experience! I highly recommend ANYONE to go and see them. No matter any problems you may have they work hard to find a way to help you out! Thank you again for putting me in a wonderful BMW X1, I LOVE it!

Vehicle information

Ext. color: Nebula Gray Pearl
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: 300101A
VIN: 2T2HZMAA1NC229268

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

INFINITI of Thousand Oaks review

Purchasing new car

Was looking at the QX60, and Edwin Alas from Thousand Oaks Infiniti,was the salesperson assisting me. Very friendly, professional, and very knowledgeable about all the details of the vehicle. I was looking for a particular color, and a few days later I got a call from Edwin saying the QX60 that I was looking for just came in! Went to look, was exactly what I was looking for! Everyone there was very friendly, from Finance managers,(Christian, Rob), salesperson Edwin! Overall experience was pleasant! Talk about service, I was having issues linking up my garage door, and I text Edwin, thinking he might suggest something, he came to the house on his day off, and linked up the garage door, and asked if I had any other questions about the car! Told me to call him, if I have any questions!!! Awesome guy! Awesome service! Never had this type of service from any car that we have purchased in the past!

Vehicle information

Ext. color: Caviar
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: SA011541S
VIN: 2T2HZMAAXNC255514

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

Lexus Santa Monica review

Tim Nelson, Service Manager

Tim is the best service manager at Lexus Santa Monica, he's funny, always happy and chipper, always eager to help in any and all ways. Tim hears me out, never disregards my comments and always makes sure my car is fixed smoothly and quickly.

Vehicle information

Ext. color: Nebula Gray Pearl
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: SS032683S
VIN: 2T2AZMAA5NC234474

Features

Convenience: Adaptive Cruise Control, Heated Seats, Keyless Entry, Keyless Start, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

Lexus Santa Monica review

Excellent experience buying my new car!

I have leased and financed a few cars in my life and I have to say how absolutely grateful and happy I am that I decided to go to Lexus Santa Monica to lease my new 2019 Lexus NX300H. From beginning to end it was the best experience I have ever had. I was helped by sales person Nima Behnia. He was very well informed about the vehicles I was test driving and answered all my questions, and boy did I hit him with a hundred questions. This was the quickest vehicle purchase ever. I think I was in and out within 3 hours. Finance dept was also great. took care of my contract quick and everything was straight forward. I didn't feel like there was any hidden anything. My new car was detailed, filled up with gas and off I went. I would definitely recommend them to my family and friends. Go GET a LEXUS!

Vehicle information

Ext. color: Caviar
Int. color: Glazed Caramel
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: SC062096S
VIN: 2T2HZMAA4NC257999

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

Lexus Santa Monica review

Great experience

My sales person was Naz . I purchased a Lexus from this dealer on 4/2/2020 . Nas was amazing she explained every details and made us feel very comfortable, welcoming she’s very kind I would recommend her to my friends and family .

Vehicle information

Ext. color: Caviar
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L228813
VIN: 2T2HZMAA6NC228813

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Reviews

Lexus Santa Monica review

We met a very helpful internet sales rep named Maria,

We met a very helpful internet sales rep named Maria, whose communication skills set her apart from the other Lexus dealerships. She was lovely and knowledgeable in person. We were paying cash and agreed on a price quickly-our only concern was how many hours it took to finalize the deal with so many attempts to sell us on maintanence packages.

Vehicle information

Ext. color: Black
Int. color: TAN
Drivetrain: Rear-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27222238
VIN: 2T2HZMAA9NC236422

Features

Convenience: Heated Steering Wheel, Navigation System, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats

Reviews

CarMax Torrance review

Great Experience

I had a wonderful experinece shopping for a used car at Carmax in Torrance. The entire staf was helpful and kind. The salesman made the process very easy.

Vehicle information

Ext. color: Black
Int. color: BLACK
Drivetrain: Rear-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27339186
VIN: 2T2HZMAA1NC253716

Features

Convenience: Heated Steering Wheel, Navigation System, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats, Memory Seat

Reviews

CarMax LAX review

No muss. No fuss.

Saw the car on the website. Transferred from another Carmax location without any hassle. Process at the dealership was professional.

Vehicle information

Ext. color: Blue
Int. color: BLACK
Drivetrain: Rear-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27330665
VIN: 2T2AZMAA7NC255147

Features

Convenience: Remote Start
Entertainment: Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats

Reviews

CarMax Burbank review

Purchased 2015 Rav 4 LE

I want to commen on our salesmen, Chase Morris. He was so helpful and work very hard to make the situation easy for us. Janet Lanoil.

Vehicle information

Ext. color: Caviar
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L231445
VIN: 2T2HZMAA7NC231445

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control

Vehicle information

Ext. color: Black
Int. color: BLACK
Drivetrain: Rear-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27452665
VIN: 2T2HZMAA4NC245657

Features

Convenience: Heated Steering Wheel, Navigation System, Remote Start
Entertainment: Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats, Memory Seat

Reviews

CarMax Canoga Park review

Good Experience.

Good Experience. Good Service. Helpful Representatives. Able to answer all my questions. Assisted in transferring to Arizona Carmax.

Vehicle information

Ext. color: Gray
Drivetrain: Front-wheel Drive
MPG: 20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: S2026572R
VIN: 2T2HZMAA2NC242546

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
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Lexus RX 350 prices by year

Model year Prices from Deals
2025 Lexus RX 350 $53,320

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $42,589, with pricing starting at $29,998.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(11 reviews)
Rating breakdown (out of 5):
  • Comfort 4.5
  • Interior 4.5
  • Performance 3.8
  • Value 3.5
  • Exterior 4.6
  • Reliability 3.9
Ratings (11 reviews)

63% of drivers recommend this car

Rating breakdown (out of 5):
  • Comfort 4.5
  • Interior 4.5
  • Performance 3.8
  • Value 3.5
  • Exterior 4.6
  • Reliability 3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.

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