Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2021 Mercedes-Benz S-Class
for sale
near
Neabsco, VA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
My boyfriend had been looking for long time to find
My boyfriend had been looking for long time to find another beautiful, unique Mercedes with specific features, and we finally found it about 4 hrs driving from NYC. What a great experience we had purchasing a convertible Mercedes with Chip, professional, kind, knowledgeable Salesperson! It was a beautiful day of September, 2024, perfect time to drive a convertible car! Since then, we've been enjoying more the beauty of weekends , the symphony of autumn colors, traveling in many places under no sky limits... With the indoor showroom, every car is clean, all of them look impacable! Everything is no pressure, they paid attention to our questions. The finance lady is awesome, especially in our case as a cash buyer. She made my partner feel very comfortable about purchase process . We would definitely drive another 3.5 -4 hours to make another purchase with Chip, MD, when I'll decide to change my car. Chip and his Team do outstanding job! I highly recommend him to get your DREAM car, you won't regret making your decision. Thank you, Chip! You rock!
Love my Mercedes
I have been driving Mercedes Benz s class vehicles for over 10 years, traded every 3-4 years and have been very happy, always have them serviced at the dealer, always received a loaner, no complaints.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
This is my second time at this dealership.
This is my second time at this dealership. I can honestly say I have never had a better experience. I told Bryan what I wanted, he had it prepped and ready before I arrived, and pricing was fair and transparent. The whole process took me less than 2 hours, which made my week!
An Absolute Dream
I have owned 6 S Class (SonderKlas) cars in my life and each and every single one has been problem free and a pure joy to own, drive, and admire. The 2021 S580 however.. Well this car is truly something special and not an incremental upgrade! This thing is crazy






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Tony at the Service Department-always provides
Tony at the Service Department-always provides outstanding customer service. He provided me continuous updates, answered all my questions, and ensured I had a pick up and drop off. I have worked with Tony numerous times now and that is why I keep returning to Farrish. Professional dealership.
Luxury
Luxury at its best, you can’t get better than that with this price range. S 580 is the way to go, the 8 cylinders are so smooth yet so sporty. This car can be Rolls Royce luxury and lamborghini urus if it wants






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Yulila was super friendly and helpful.
Yulila was super friendly and helpful. She didn’t pressure us and gave us great info. Super happy with our purchase






Used
2021 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Customer service was very good.
Customer service was very good. I flew in from out of town and they picked me at the airport.






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I had a great buying experience.
I had a great buying experience. My salesman, Paul was wonderful and the finance department was great as well. Definitely recommend Mercedes of Arlington






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Refreshing !
Refreshing ! I brought a SL550 Benz , worked with Mason best experience from a car dealership I had to date, from the first day I called to last day out the door with the car . They waited on me and for me & I appreciate that highly recommended. Shot out to Haas & Chris! Sending all friend & fam. Mr & Mrs Mark F.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
AWESOME DEALERSHIP AND STAFF❣️ GREAT SELECTIONS 2 CHOOSE
AWESOME DEALERSHIP AND STAFF❣️ GREAT SELECTIONS 2 CHOOSE FROM🚘🚙 THANK U 4 MY NEW SUV🚙🤍💃🏽🥳🎉






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I did some research before going to UAC and everyone
I did some research before going to UAC and everyone lived up to the reviews that I read. It was great family atmosphere and I felt like I knew them for ages. When I walk in the door with no appointment I was greeted by Baker who was very professional and polite. I informed him about the car that I was interested in and he gave all the details, Carfax information and explained all components from the beginning until I left. Finance went extremely smooth I was in and out. It’s no words that I can explain about Jessica like I said early I felt like I known her for years. She treated me more like friend/family not just like a customer. Jessica was extremely accurate with numbers and we discussed the payment and interest rate that will suit me. She is passionate about doing the best for you. Overall outstanding experience. If you looking for luxury car or truck please check them out. I will return.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I post a review on June 7 2025 and today July 26, 2025 we
I post a review on June 7 2025 and today July 26, 2025 we had meeting with the manager James and he settled the price issue we had with the purchase of Honda civic 2016. Thank you James






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Meet with Johnathan today to trade my car in for a
Meet with Johnathan today to trade my car in for a widebody challenger scatpack great service all around and great deal will shop with them again. Thanks Johnathan and albert
There are 20 matching cars close to your year range.






Used
2023 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class
Vehicle information
Features






Used
2023 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 500 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz S-Class S 500 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz S-Class S 560
Vehicle information
Features



Used
2020 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
-
Prev - 1
-
Next
Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2022 Mercedes-Benz S-Class | $57,995 | 8 Good deals |
2016 Mercedes-Benz S-Class | $14,951 | 6 Good deals |
2015 Mercedes-Benz S-Class | $14,444 | 15 Good deals |
2014 Mercedes-Benz S-Class | $18,119 | 4 Good deals |
About the 2021 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2021 Mercedes-Benz S-Class cost?
The 2021 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 S-Class is $66,193, with pricing starting at $47,995.
What is the MPG of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class offers up to 20 MPG in city driving and 29 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz S-Class reliable?
The 2021 Mercedes-Benz S-Class has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 S-Class owners.
Is the 2021 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
100% of drivers recommend this car
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $109,800 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 560 (2 styles)
Style | |
---|---|
S 560 Cabriolet | S 560 4MATIC Coupe |
Inventory price | |
Starting at $140,000 | Starting at $131,400 |
Combined MPG | |
20 | 20 |
Engine | |
463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) | 463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $116,300 |
Combined MPG |
20 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz S-Class
Compare the 2021 Mercedes-Benz S-Class
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
${award_blurb}
${award_two_blurb}