Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Mercedes-Benz S-Class
for sale
near
Bridgeview, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
MBZ S-class always 5 ***** vehicle.
MBZ S-class always 5 ***** vehicle. The most luxurious , comfortable, car I ever drove . I highly recommend it . My old Mercedes S-class has 200,000 miles and not a single problem.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
A Wonderful Overall Experience
I just picked up my S580 Lux-Line in Emerald Green over Sienna Brown, and I am absolutely thrilled with the purchase. I have owned five S-Class models since 2010, including this new one, and I can say this is the best iteration yet from an overall perspective. While I still think the W222 was the best-looking (especially my 2019 S560 with the refreshed look and AMG pack), this new one does not disappoint at all. The Emerald Green is stunning in the sunlight, my favorite color yet. And the interior is on another level from a luxury and tech standpoint. I loved the interiors of all the S-Class models I've owned, but this current one is my favorite. The seats are super supportive, and the vast amount of tech is amazing. The new infotainment screen takes time to learn and get used to, but I feel the "Hey, Mercedes" function makes doing small things like putting in a Navigation request easier than going through the main screen. From a driving perspective, the ride is the best yet, just like gliding on a cloud. I've been lucky to have driven Bentley's and Rolls-Royce's in my lifetime, and this ride is as close as I've seen the S-Class come to being even with those vehicles on this front. And, the V8 is plenty punchy when needed, so it can be a fun vehicle to take on windy roads if you so desire. Overall, a wonderful vehicle and a bargain when you compare it to the other super-luxury vehicles on sale. I'm looking forward to the next few years of owning such an awesome car.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Motor Cars of Chicago is a great dealership to work with!
Motor Cars of Chicago is a great dealership to work with! I purchased a used Dodge 3500 there and was provided a wonderful experience from the moment I walked in the door. Mark assisted me through the process and was helpful and very pleasant to work with! Highly recommend Mark AND this dealership!






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Staff were all kind helpful and very professional The
Staff were all kind helpful and very professional The staff allowed me time to look at a car. Price was very competitive






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Armin was amazing to work with, went above and beyond in
Armin was amazing to work with, went above and beyond in more ways than one, to ensure we had a pleasant experience. We brought the car while in Colorado, having it shipped. Was exactly we expected. Highly recommend!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Bought a Bentley GT Speed from Dan and his team!
I recently bought a Bentley. Dan and his team are great!! My salesman Dimitri and finance guy Ibrahim were fantastic. I couldn’t ask for a better team or service. The service they give is presidential. They treat you like family and. I will continue to buy cars for my wife, myself, and my business from them. They are great people to do business with. Top notch, classy, and good people.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
The dealership had a great selection of quality used
The dealership had a great selection of quality used cars, all well-maintained and reasonably priced. I appreciated their transparency and honesty throughout the process, including providing detailed vehicle history reports. The financing process was also seamless, offering several options and explaining everything clearly. I left feeling confident and satisfied with my purchase. Overall, I highly recommend Affinity Auto Sales to anyone looking for a reliable used car and a pleasant buying experience. Thank you to the entire team for making this such a positive experience!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Top-notch dealership for specialty vehicles!
Outstanding dealership!! They have a meticulously selected inventory of phenomenal luxury, classic and high-end vehicles at great prices. After searching for months, I was fortunate to find a muscle car gem at Platinum Motorsports – a very low-mile 2001 Camaro SS 6-speed in excellent condition for being 20+ years old! The guys there are all top-notch in the business; they genuinely care about their clients and are not just in it to make a quick sale. Manny, Zico and Rick have high integrity, are very communicative and helpful, and went above and beyond to get my new ride shipped to me promptly (even in the middle of a Chicago blizzard!) I can't say enough good things about the crew there, and I enthusiastically recommend them. If you’re thinking of buying one of the outstanding vehicles you see on their site, do it – you won’t regret it!!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Steve was an excellent sales rep.
Steve was an excellent sales rep. Ultimo has a great stable of cars to select from. Steve went out of his way to help me with my trade in, new summer wheels & tires and answered all of my questions accurately.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Excellent
Mark made my experience the best! Quick simple and easy. No run arounds. Will be returning again the In the future he is the best!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
THE LUXURY EXPERIENCE
I made an appointment on line. When I arrived they had a loaner full of gas waiting for me. Then when I picked up my Bentley it looked brand new again. That is what I call "THE LUXURY EXPERIENCE !!!!!!!!"






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I had the absolute pleasure of working with Omar during
I had the absolute pleasure of working with Omar during my recent car purchase, and I can’t recommend him highly enough. From the moment I walked in, Omar was friendly, knowledgeable, and completely focused on finding the right car for me—not just making a sale. He took the time to understand my needs, answered all my questions with patience and clarity, and guided me through every step of the process with honesty and professionalism. What really stood out was how transparent and low-pressure he was, which made the experience stress-free and enjoyable. Thanks to Omar, I drove away in a car I love and with a deal that I felt great about. If you’re looking for someone who genuinely cares about helping you find the right vehicle, Omar is your guy. I’ll definitely be recommending him to friends and family!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Wonderful experience from first contact through sale.
Wonderful experience from first contact through sale. Albert Tulo was knowledgeable, friendly, and efficient with processing my used car sale! Highly recommend!



Mercedes-Benz Certified
2022 Mercedes-Benz S-Class
Vehicle information






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
No pressure.
No pressure. Buying process was fast and easy. It was a pleasure to do business with.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Very responsive and got back to me promptly and checked
Very responsive and got back to me promptly and checked in after the initial email.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Very responsive.
Very responsive. Very knowledgeable about the Tesla Model S Plaid. Friendly and great communications from the first phone call to the last.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Chris and Matt are all world!
Chris and Matt are all world! Love my car and our entire experience buying from them. Very responsive and dependable. Knowledgeable as well. Joey
-
Prev - 1
- 2
-
Next
Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $114,990 | 1 Good deal |
2024 Mercedes-Benz S-Class | $84,999 | 4 Good deals |
2023 Mercedes-Benz S-Class | $63,985 | 6 Good deals |
2021 Mercedes-Benz S-Class | $56,639 | 2 Good deals |
2016 Mercedes-Benz S-Class | $18,999 | 5 Good deals |
2015 Mercedes-Benz S-Class | $23,991 | 8 Good deals |
About the 2022 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2022 Mercedes-Benz S-Class cost?
The 2022 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 S-Class is $71,781, with pricing starting at $38,000.
What is the MPG of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class offers up to 21 MPG in city driving and 30 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2022 Mercedes-Benz S-Class reliable?
The 2022 Mercedes-Benz S-Class has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 S-Class owners.
Is the 2022 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
50% of drivers recommend this car
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $111,100 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $117,700 |
Combined MPG |
19 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Mercedes-Benz S-Class
Compare the 2022 Mercedes-Benz S-Class
2022 Mercedes-Benz S-Class by city
-
2022 Mercedes-Benz S-Class in Hickory Hills, IL
6 Great Deals out of 26 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Justice, IL
6 Great Deals out of 27 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Burbank, IL
6 Great Deals out of 26 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Bedford Park, IL
6 Great Deals out of 27 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Chicago Ridge, IL
6 Great Deals out of 26 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Palos Hills, IL
6 Great Deals out of 26 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Summit, IL
6 Great Deals out of 28 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Hodgkins, IL
6 Great Deals out of 27 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Oak Lawn, IL
6 Great Deals out of 26 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Worth, IL
6 Great Deals out of 26 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Hometown, IL
6 Great Deals out of 26 listings starting at $55,991
-
2022 Mercedes-Benz S-Class in Willow Springs, IL
6 Great Deals out of 27 listings starting at $55,991
Mercedes-Benz S-Class trims
-
Mercedes-Benz S-Class 2022 S 580 4MATIC
5 Great Deals out of 23 listings starting at $55,991
2022 Mercedes-Benz S-Class by body style
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}