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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2022 Mercedes-Benz S-Class
for sale
near
Santa Ana, CA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
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Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
AutoNation proved to be consummate professions, living up
AutoNation proved to be consummate professions, living up to the recommendation to go there. They know their business and have amazing inventory. I would recommend them.
A Wonderful Overall Experience
I just picked up my S580 Lux-Line in Emerald Green over Sienna Brown, and I am absolutely thrilled with the purchase. I have owned five S-Class models since 2010, including this new one, and I can say this is the best iteration yet from an overall perspective. While I still think the W222 was the best-looking (especially my 2019 S560 with the refreshed look and AMG pack), this new one does not disappoint at all. The Emerald Green is stunning in the sunlight, my favorite color yet. And the interior is on another level from a luxury and tech standpoint. I loved the interiors of all the S-Class models I've owned, but this current one is my favorite. The seats are super supportive, and the vast amount of tech is amazing. The new infotainment screen takes time to learn and get used to, but I feel the "Hey, Mercedes" function makes doing small things like putting in a Navigation request easier than going through the main screen. From a driving perspective, the ride is the best yet, just like gliding on a cloud. I've been lucky to have driven Bentley's and Rolls-Royce's in my lifetime, and this ride is as close as I've seen the S-Class come to being even with those vehicles on this front. And, the V8 is plenty punchy when needed, so it can be a fun vehicle to take on windy roads if you so desire. Overall, a wonderful vehicle and a bargain when you compare it to the other super-luxury vehicles on sale. I'm looking forward to the next few years of owning such an awesome car.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
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Reviews
Superb all the way around!
Superb all the way around!!! Never had a more pleasant experience with a dealership. Giovanna, Greg and Fred all amazing.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I never write reviews….
I never write reviews…. BUT!!! A HUGE thanks to salesman JEFF! We appreciated his professionalism and passion to help us find our new car. Even after buying ours, he was so kind and quick to answer any of our questions. We are definitely recommending Jeff to our friends and families!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
This is my first experience with Fletcher Jones and it
This is my first experience with Fletcher Jones and it has been a good one so far. Buying a car long distance, sight unseen is always a bit of a challenge and potentially a risk. I feel very good about the responsiveness and customer care provided by Fletcher Jones staff. As car delivery is still in front of us, the jury is out on this experience, but I anticipate a very positive outcome. Fletcher Jones reputation provided a lot of confidence.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
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Reviews
Ashley is top notch with knowledge and service and
Ashley is top notch with knowledge and service and patience! Everyone at the dealership is helpful and accommodating. Thanks for everything, Ashley!






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
I saw that Mercedes Benz just announced some new
I saw that Mercedes Benz just announced some new incentives and went to the dealership to check out some GLE hybrids. I wasn?t expecting to purchase a car that day, however, Solomon Wang and Sam Lee were top notch in giving me an incredible deal. The process was fairly straightforward and easy, with minimal pressure.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
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Reviews
Good service on the my lease purchase last month it was
Good service on the my lease purchase last month it was really easy process with the help a salesperson only took us around 2 hours waiting all paperwork.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
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Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Mercedes-Benz Certified
2022 Mercedes-Benz S-Class
Vehicle information
Reviews
Satisfied
Well, our experience with Tony was Fantastic! We found a car on the internet that we wanted and proceeded to go out there to purchase. Upon our arrival, Tony greeted us without delay and processed our request. We were out of the dealership within 1.5 hours, now that's a record! He got us our approval in a timely manner and it was all good!!! I would definitely work with them again. Now about the markup, it seems all the dealerships mark up and in order to stay in business so I don't worry too much. Plus the fact the car we purchased was in pristine condition with low miles it was worth the markup and the drive. I am a satisified!



Mercedes-Benz Certified
2022 Mercedes-Benz S-Class
Vehicle information
Reviews
Every one who we talk to in the buying process was great
Every one who we talk to in the buying process was great ! Definitely will be back soon Thank you






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
It was a great experience from beginning to end.
It was a great experience from beginning to end. I got exactly what I wanted and it was delivered to me in perfect condition. I can’t thank them enough.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
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Reviews
Private Collection is the place to go for exotica
We were extremely impressed with their showroom, delivery, no haggle pricing so we did not end up spending a day waiting for the sale manager to work you into all the stuff you do not need. I came to pick up the car next Monday they have the car all detailed up for us. I will return for my next purchase.
Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
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Reviews
I had such a great experience at Mercedes-Benz of
I had such a great experience at Mercedes-Benz of Riverside! Christian was incredibly helpful from start to finish—he really took the time to listen to what I was looking for and helped me find the exact C300 I had in mind. He was patient, knowledgeable, and made the whole process smooth and stress-free. I couldn’t be happier with my new car! I would definitely recommend Christian and this dealership to anyone in the market for a Mercedes.
There are 20 matching cars close to your year range.






Mercedes-Benz Certified
2020 Mercedes-Benz S-Class S 580 4MATIC
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Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
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Used
2023 Mercedes-Benz S-Class S 580e
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Used
2021 Mercedes-Benz S-Class S 580
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Mercedes-Benz Certified
2024 Mercedes-Benz S-Class S 580 4MATIC
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Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
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Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Mercedes-Benz Certified
2023 Mercedes-Benz S-Class
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Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Features






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2023 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2023 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Used
2020 Mercedes-Benz S-Class AMG S 63
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Used
2023 Mercedes-Benz S-Class S 580 4MATIC
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Used
2024 Mercedes-Benz S-Class S 580 4MATIC
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Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $113,495 | |
2023 Mercedes-Benz S-Class | $61,599 | 5 Great deals |
2021 Mercedes-Benz S-Class | $61,933 | 4 Good deals |
About the 2022 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2022 Mercedes-Benz S-Class cost?
The 2022 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 S-Class is $71,880, with pricing starting at $48,426.
What is the MPG of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class offers up to 21 MPG in city driving and 30 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2022 Mercedes-Benz S-Class reliable?
The 2022 Mercedes-Benz S-Class has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 S-Class owners.
Is the 2022 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
50% of drivers recommend this car
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $111,100 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $117,700 |
Combined MPG |
19 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Mercedes-Benz S-Class
Compare the 2022 Mercedes-Benz S-Class
2022 Mercedes-Benz S-Class by city
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2022 Mercedes-Benz S-Class in Placentia, CA
6 Great Deals out of 20 listings starting at $55,995
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6 Great Deals out of 20 listings starting at $55,995
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2022 Mercedes-Benz S-Class in Cypress, CA
5 Great Deals out of 21 listings starting at $55,995
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2022 Mercedes-Benz S-Class in Buena Park, CA
6 Great Deals out of 21 listings starting at $55,995
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5 Great Deals out of 21 listings starting at $55,995
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2022 Mercedes-Benz S-Class in Rossmoor, CA
5 Great Deals out of 21 listings starting at $55,995
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2022 Mercedes-Benz S-Class in La Palma, CA
5 Great Deals out of 21 listings starting at $55,995
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