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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2022 Mercedes-Benz S-Class
for sale
near
Spring House, PA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Everyone, from Austin the sales person to Jessica the
Everyone, from Austin the sales person to Jessica the sales assistant to the pre-owned sales manager and finance person, could not have been more friendly, helpful, or accommodating. I have owned and leased probably in excess of 100 cars in my life and this was by far the best experience I've ever had.
MBZ S-class always 5 ***** vehicle.
MBZ S-class always 5 ***** vehicle. The most luxurious , comfortable, car I ever drove . I highly recommend it . My old Mercedes S-class has 200,000 miles and not a single problem.






Used
2022 Mercedes-Benz S-Class S 500 4MATIC
Vehicle information
Features
Reviews
Originally planned on getting a Genesis but fell in love
Originally planned on getting a Genesis but fell in love with the palisade. Big thanks to Joseph for making the process easy
A Wonderful Overall Experience
I just picked up my S580 Lux-Line in Emerald Green over Sienna Brown, and I am absolutely thrilled with the purchase. I have owned five S-Class models since 2010, including this new one, and I can say this is the best iteration yet from an overall perspective. While I still think the W222 was the best-looking (especially my 2019 S560 with the refreshed look and AMG pack), this new one does not disappoint at all. The Emerald Green is stunning in the sunlight, my favorite color yet. And the interior is on another level from a luxury and tech standpoint. I loved the interiors of all the S-Class models I've owned, but this current one is my favorite. The seats are super supportive, and the vast amount of tech is amazing. The new infotainment screen takes time to learn and get used to, but I feel the "Hey, Mercedes" function makes doing small things like putting in a Navigation request easier than going through the main screen. From a driving perspective, the ride is the best yet, just like gliding on a cloud. I've been lucky to have driven Bentley's and Rolls-Royce's in my lifetime, and this ride is as close as I've seen the S-Class come to being even with those vehicles on this front. And, the V8 is plenty punchy when needed, so it can be a fun vehicle to take on windy roads if you so desire. Overall, a wonderful vehicle and a bargain when you compare it to the other super-luxury vehicles on sale. I'm looking forward to the next few years of owning such an awesome car.






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Best MB dealer for Sprinter Inventory
Excellent dealer to find the perfect Sprinter for your needs regardless what state you reside in. Just flew in from Detroit 12/28 to purchase 2022 170” Crew VanFrom Sprinter Sales Manager Jay Posnack. Second Sprinter I purchased from him. All communication was clear and concise with absolutely no pressure. I found dealer stock to be without equal, offering 22 &23 In all trim levels. If you are looking for a Sprinter van consider calling Jay.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
This dealership is one of the nicer ones and Steve was a
This dealership is one of the nicer ones and Steve was a great help! They helped me resolve some of my automatic issues that I was having.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
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Reviews
happy Customer
Avi Auto Sales Inc. is my primary choice for buying a used car from now on and I am willing to travel to their dealership in Magnolia, NJ for 5+ hours from Upstate New York for my next car. They have an impressive selection if fine automobiles however, it is a rare kind of dedication to customer’s satisfaction that impressed me most. They spend hours on a Sunday afternoon trying to get my disabled car back on the road. I wouldn’t hesitate doing business with them on an Old-Fashioned Handshake!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Excellent service!
Excellent service! They made car buying quick and easy! No pressure sales. They have great cars on the lot!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Anyone there doing his best to satisfy the customer I was
Anyone there doing his best to satisfy the customer I was definitely recommended anyone to go there for shopping.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Top notch place.
Top notch place. Very easy to do business with, everyone was friendly and inviting. Looking forward to doing business with them again.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Dealership was incredibly responsive to my inquiry - they
Dealership was incredibly responsive to my inquiry - they were really great to work with. I ended up buying a car elsewhere, but J&S Autohaus was a pleasure to deal with.
There are 16 matching cars close to your year range.






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2020 Mercedes-Benz S-Class S 580 4MATIC
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2021 Mercedes-Benz S-Class S 580 4MATIC
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2020 Mercedes-Benz S-Class S 560 4MATIC
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2021 Mercedes-Benz S-Class S 580 4MATIC
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Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Used
2021 Mercedes-Benz S-Class S 580
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Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Used
2023 Mercedes-Benz S-Class S 580 4MATIC
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Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $125,846 | 1 Good deal |
2021 Mercedes-Benz S-Class | $56,995 | 4 Good deals |
About the 2022 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2022 Mercedes-Benz S-Class cost?
The 2022 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 S-Class is $72,304, with pricing starting at $36,995.
What is the MPG of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class offers up to 21 MPG in city driving and 30 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2022 Mercedes-Benz S-Class reliable?
The 2022 Mercedes-Benz S-Class has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 S-Class owners.
Is the 2022 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
50% of drivers recommend this car
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $111,100 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $117,700 |
Combined MPG |
19 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Mercedes-Benz S-Class
Compare the 2022 Mercedes-Benz S-Class
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