Own a 2004 with over 330,000 miles. It just keeps running. As a landlord, I use it somewhat like a truck, it holds tools in the rear. Can transport 4x8 sheets of drywall and plywood with some shuffling. Hauled 1200 lbs of concrete bags behind the front row seats many times. I use the 3rd row for passengers. Have removed the second row and never replaced them. Change the oil every 5Kmi because that interval is easy to remember. And the typical timing belt and water pump (while exposed) every 100K. Just let the dealer do the brakes, they last years and don't wobble. Of course the automatic doors gave out at 200K, but you kind of expect that. They still work manually. A few strange items like a steering rack at 150K and vent window hinge gave out around then. And the drivers seat heater gave up. The problem is that this van is so good, I really hate to replace it. It's a good problem to have. I'm not hauling concrete in a brand new $50,000 Sienna.

A word of warning- the oil cooler pipe should have been recalled because it can rupture and let all of the oil out of the engine which can cause major damage to the engine which is what happened to me recently in late 2022 with 204,000 miles on it. I loved it prior to that, The dealer wants $7,400 to repair the engine. They have been servicing it since I bought it used in November, 2015 with about 68,000 miles on it. I told them they should have warned me about this possible problem but the said Toyota did not want them to say anything to customers about the possible problem. Toyota redesigned the part but I didn’t know about the problem until it was too late. They sent out a warranty extension but it was sent to the previous owner before I bought it, so I never knew about it. Toyota should have issued a recall on the oil cooler pipe! No help from Toyota or the dealer who has been servicing the vehicle.

Ours has 220,000 miles on it in the year 2021. We had to put a new transmission in it a few years ago, but it has had no other problems. We purchased it used in 2011 with 40,000+ miles on it. It had been a rental car, which might account for the rough transmission.