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Used 2021 Lexus ES 350 for sale near Fort Myers, FL

Filters 5 Year Model Price & payment Make Mileage Body style All filters
1 match 30 miles from 33916
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Est. $400 /mo*
Down Payment
$0
Net trade-in value
$0
Months
72
APR
7.0%
Sales tax
0.0%

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

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2021 Lexus ES 350 Base
2021 Lexus ES 350 Base
2021 Lexus ES 350 Base
2021 Lexus ES 350 Base
2021 Lexus ES 350 Base
2021 Lexus ES 350 Base View all 26 photos

Used

2021 Lexus ES 350 Base

33,092 mi.
$31,970
Est. $580/mo*
Free CARFAX Report
AutoNation USA Fort Myers
(78 reviews)
Fort Myers, FL (3 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Nightfall Mica
Int. color: Black
Drivetrain: Front-wheel Drive
MPG: 22-32
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iE/VVT-i variable valv
Stock #: MU084844
VIN: 58ADZ1B10MU084844

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Stability Control

Reviews

AutoNation USA Fort Myers review

Had a tremendous experience at AutoNation USA Fort Myers.

April 30, 2025
By Vuyo Smith from Fort Myers

Had a tremendous experience at AutoNation USA Fort Myers. The service was top notch from beginning to end. Jazmyn worked hard to get me done. I appreciate the staff so much. Highly recommend!

2021 Lexus ES 350 Base review

The most reliable car I’ve owned, it has style, comfort

January 29, 2025
By Cliff from Santa Clarita, Ca
Owns this car

The most reliable car I’ve owned, it has style, comfort and to many extras to list. We went from a Volvo S60 to this car and we are not disappointed!

There are 11 matching cars close to your year range.

2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport View all 21 photos

Used

2022 Lexus ES 350 F Sport

12,663 mi.
$40,995
Est. $744/mo*
Get the AutoCheck Report
Germain BMW of Naples
Naples, FL (25 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Iridium
Int. color: Red
Drivetrain: Front-wheel Drive
MPG: 22-31
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: D251151B
VIN: 58AGZ1B19NU124658

Features

Convenience: Adaptive Cruise Control, Heated Seats, Heated Steering Wheel, Keyless Entry, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats, Memory Seat
2019 Lexus ES 350 350
2019 Lexus ES 350 350
2019 Lexus ES 350 350
2019 Lexus ES 350 350
2019 Lexus ES 350 350
2019 Lexus ES 350 350 View all 27 photos

Used

2019 Lexus ES 350 350

27,577 mi.
$30,988 $1,000 price drop
Est. $563/mo*
Get the AutoCheck Report
Germain Lexus of Naples
Naples, FL (24 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Matador Red Mica
Int. color: Black
Drivetrain: Front-wheel Drive
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: XP12310A
VIN: 58ABZ1B11KU032207

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Remote Start
Entertainment: Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio, USB Port
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Brake Assist, Lane Departure Warning, Stability Control
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport
2022 Lexus ES 350 F Sport View all 27 photos

Used

2022 Lexus ES 350 F Sport

33,007 mi.
$37,888 $600 price drop
Est. $688/mo*
Get the AutoCheck Report
Germain Honda
Naples, FL (30 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Ultra White
Int. color: Red
Drivetrain: Front-wheel Drive
MPG: 22-31
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: H251240A
VIN: 58AGZ1B15NU123457

Features

Convenience: Adaptive Cruise Control, Heated Seats, Heated Steering Wheel, Keyless Entry, Navigation System, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats, Memory Seat
2019 Lexus ES 350 F Sport
2019 Lexus ES 350 F Sport
2019 Lexus ES 350 F Sport
2019 Lexus ES 350 F Sport
2019 Lexus ES 350 F Sport
2019 Lexus ES 350 F Sport View all 34 photos

Used

2019 Lexus ES 350 F Sport

79,127 mi.
$25,998
Est. $472/mo*
Free CARFAX Report
Bonita Beach Mitsubishi
Bonita Springs, FL (22 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Ultra White
Int. color: Black w/Hadori Aluminum
Drivetrain: Front-wheel Drive
MPG: 22-31
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iE/VVT-i variable valv
Stock #: P0207B
VIN: 58ABZ1B19KU012478

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment: Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Memory Seat
2019 Lexus ES 350 Luxury
2019 Lexus ES 350 Luxury
2019 Lexus ES 350 Luxury
2019 Lexus ES 350 Luxury
2019 Lexus ES 350 Luxury
2019 Lexus ES 350 Luxury View all 31 photos

Used

2019 Lexus ES 350 Luxury

47,573 mi.
$29,998
Est. $545/mo*
Free AutoCheck Report
CarMax Ft. Myers
Fort Myers, FL (3 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Black
Int. color: BROWN
Drivetrain: Rear-wheel Drive
MPG: 22-33
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 26960007
VIN: 58ABZ1B14KU002537

Features

Convenience: Heated Steering Wheel, Navigation System, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning
Seating: Leather Seats, Memory Seat
2019 Lexus ES 350 F-Sport
2019 Lexus ES 350 F-Sport
2019 Lexus ES 350 F-Sport
2019 Lexus ES 350 F-Sport
2019 Lexus ES 350 F-Sport
2019 Lexus ES 350 F-Sport View all 31 photos

Used

2019 Lexus ES 350 F-Sport

105,801 mi.
$23,998
Est. $436/mo*
Free AutoCheck Report
CarMax Ft. Myers
Fort Myers, FL (3 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Black
Int. color: BURGUNDY
Drivetrain: Rear-wheel Drive
MPG: 22-31
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27313091
VIN: 58ABZ1B10KU009615

Features

Convenience: Heated Steering Wheel, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats, Memory Seat
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base View all 24 photos

Used

2022 Lexus ES 350 Base

10,733 mi.
$35,950 $1,036 price drop
Est. $653/mo*
Free CARFAX 1-Owner Report
Germain Toyota
Naples, FL (24 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Iridium
Int. color: Palomino
Drivetrain: Front-wheel Drive
MPG: 22-32
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iE/VVT-i variable valv
Stock #: SP123408
VIN: 58ADZ1B1XNU123408

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Keyless Start, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base
2022 Lexus ES 350 Base View all 27 photos

Used

2022 Lexus ES 350 Base

30,682 mi.
$34,888
Est. $633/mo*
Get the AutoCheck Report
Germain Lexus of Naples
Naples, FL (24 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Matador Red Mica
Int. color: Palomino
Drivetrain: Front-wheel Drive
MPG: 22-32
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V6 24V PDI DOHC
Stock #: L251140A
VIN: 58ADZ1B16NU122644

Features

Convenience: Adaptive Cruise Control, Keyless Entry, Navigation System, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Backup Camera, Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats
2023 Lexus ES 350 F-SPORT Handling
2023 Lexus ES 350 F-SPORT Handling
2023 Lexus ES 350 F-SPORT Handling
2023 Lexus ES 350 F-SPORT Handling
2023 Lexus ES 350 F-SPORT Handling
2023 Lexus ES 350 F-SPORT Handling View all 31 photos

Used

2023 Lexus ES 350 F-SPORT Handling

11,084 mi.
$41,998
Est. $763/mo*
Free AutoCheck Report
CarMax Ft. Myers
Fort Myers, FL (3 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Gray
Int. color: WHITE
Drivetrain: Rear-wheel Drive
MPG: 22-31
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27312971
VIN: 58AJZ1B12PU148289

Features

Convenience: Heated Steering Wheel, Navigation System
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior: Alloy Wheels
Safety: Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating: Leather Seats, Memory Seat
2019 Lexus ES 350 Luxury

Used

2019 Lexus ES 350 Luxury

49,607 mi.
$29,981
Est. $544/mo*
Free CARFAX 1-Owner Report
Lexus of Fort Myers
Fort Myers, FL (8 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Eminent White Pearl
Int. color: Chateau
Drivetrain: Front-wheel Drive
MPG: 22-33
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iE/VVT-i variable valv
Stock #: KU026113
VIN: 58ABZ1B16KU026113

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment: Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats, Memory Seat
2022 Lexus ES 350 Ultra Luxury

Used

2022 Lexus ES 350 Ultra Luxury

33,479 mi.
$42,026
Est. $763/mo*
Free CARFAX 1-Owner Report
Lexus of Fort Myers
Fort Myers, FL (8 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Caviar
Int. color: Black w/Black Open Pore
Drivetrain: Front-wheel Drive
MPG: 22-32
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iE/VVT-i variable valv
Stock #: NU129009
VIN: 58AFZ1B13NU129009

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, Satellite Radio, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats, Memory Seat
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Lexus ES 350 prices by year

Model year Prices from Deals
2025 Lexus ES 350 $43,988 3 Good deals

About the 2021 Lexus ES 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
26
Transmission
8-Speed A/T
Engine
302.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus ES 350
FAQs

How much does the 2021 Lexus ES 350 cost?

The 2021 Lexus ES 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 ES 350 is $32,643, with pricing starting at $22,365.

What is the MPG of the 2021 Lexus ES 350?

The 2021 Lexus ES 350 offers up to 22 MPG in city driving and 32 MPG on the highway for a combined rating of 26 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus ES 350?

The 2021 Lexus ES 350 compares to and/or competes against the following vehicles:

Is the 2021 Lexus ES 350 reliable?

The 2021 Lexus ES 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 ES 350 owners.

Is the 2021 Lexus ES 350 a good sedan?

Below are the Cars.com consumer ratings for the 2021 Lexus ES 350.

(15 reviews)
Rating breakdown (out of 5):
  • Comfort 4.9
  • Interior 4.9
  • Performance 5.0
  • Value 4.9
  • Exterior 5.0
  • Reliability 5.0
Ratings (15 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
  • Comfort 4.9
  • Interior 4.9
  • Performance 5.0
  • Value 4.9
  • Exterior 5.0
  • Reliability 5.0
Trims

ES 350 (1 style)

Style
ES 350 FWD
Inventory price
Starting at $40,000
Combined MPG
26
Engine
302.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

ES 350 F SPORT (1 style)

Style
ES 350 F SPORT FWD
Inventory price
Starting at $45,800
Combined MPG
25
Engine
302.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

ES 350 Luxury (1 style)

Style
ES 350 Luxury FWD
Inventory price
Starting at $45,200
Combined MPG
26
Engine
302.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

ES 350 Ultra Luxury (1 style)

Style
ES 350 Ultra Luxury FWD
Inventory price
Starting at $49,000
Combined MPG
26
Engine
302.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.

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Basics
Lexus models
ES 350 trims
Price & payment Full Price Monthly
‡Monthly budget search results are estimated based on a 72-month loan term with $0 down payment, $0 trade-in value, 0.0 % sales tax and 7.0 % APR. Inputs can be personalized using the calculator.
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Drivetrain
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