Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Lexus RX 350
for sale
near
Raleigh, NC
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
I am so grateful to Brittany Rush, my favorite service
I am so grateful to Brittany Rush, my favorite service manager at Fred Anderson Nissan. I always receive a warm welcome with a warm smile from her. She really makes certain that I receive the best service and my car is washed and vacuumed. Thank you Brittany!
Love this car.
Love this car. Sitting in the driver’s seat is so comfortable. Silky smooth engine. Rides so nice and quiet. We have looked for this color Grecian water for a long time. Wanted no newer than a 2022 because we didn’t want the 4 cylinder. The 3.5 V6 runs so smooth. Would definitely recommend the purchase of this SUV.






Vehicle information
Features
Reviews
Taylor Lynch
Taylor Lynch made my wife me feel comfortable when searching for a good used Honda. He did not attack us like wolves do in the brand name dealerships . He was Honest, professional, knowledgeable about his profession. I would definitely recommend Taylor Lynch and the Carmax on Glenwood Ave. to all of my friends and family. I would recommend Carmax to anyone searching for a car. No hassles, no pressure, just good honest to goodness salemanship.
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Great Experience
We have recently purchased a vehicle from Leith Lincoln and we were very pleased with the service there. Our salesman, Chris, was very helpful and never made us feel pressured into making a purchase. And once we made the decision to buy the vehicle the process went fast. Overall we are very pleased with our experience there. We would highly recommend Leith Lincoln.
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Hello I had an outstanding experience with Ty Smith at
Hello I had an outstanding experience with Ty Smith at Durham Johnson Lexus Service! I didn’t even have an appointment, but Tyler went above and beyond to fit me in without hesitation. From the moment I arrived, he greeted me with a warm smile and a genuine willingness to help. Tyler is incredibly knowledgeable, professional, and attentive , he made sure I understood every detail of the service process and kept me updated along the way. What really stood out was how seamless and stress-free he made the entire visit, turning what could have been an inconvenience into a truly positive experience. If you’re bringing your Lexus in for service, I highly recommend asking for Tyler. He truly represents the best of Durham Johnson Lexus, top-tier service with a personal touch! Thank you, W. Rogers
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
Had an absolutely wonderful experience buying a used
Had an absolutely wonderful experience buying a used Lexus NX 200t! Aqeel and Steven were both very knowledgeable, patient and understanding, and this made the experience so much less stressful! Because of them both the whole car buying process was a breeze! Can’t recommend highly enough!
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Johnson Lexus is the best dealership to visit for
Johnson Lexus is the best dealership to visit for professionalism and speedy service. I would definitely recommend Johnson Lexus to anyone looking for a luxury car and professional services.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
I had a great experience.
I had a great experience. Mike Brown made everything seem so effortless. Would highly recommend.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Johnson has been an excellent dealership for my Lexus SUV
Johnson has been an excellent dealership for my Lexus SUV needs when it comes to service and after sale needs Taylor who is in the service department ,took excellent care of me in the last service I had done to the vehicle.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Lincoln Corsair
Great experience with Leith Lincoln , Vinny and Casey. I originally went to only test drive a vehicle so I could order one online with all the features I wanted. When I arrived Vinny met me outside and was very attentive to listening to what I was looking for. Along with everyone else looking for a new vehicle I knew there was a limited amount to choose from and I did not want to settle. Vinny provided top notch service to me and stayed with me the entire process. Which by the way only took a matter of hours to facilitate. I appreciate the attention to detail both Vinny and Casey provided.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Rene was awesome!
Rene was awesome! Easy, smooth and upfront transaction. No hidden fees or surprises. Highly recommend.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Great service experience.
Always a good experience for me. Friendly staff, clear explanation of any service items required, and reasonable wait time. Will continue to have my Jeeps serviced with Leith.






Used
2022 Lexus RX 350 Premium
Vehicle information
Features
Reviews
Lewis is one of the best customer service agents!
Lewis is one of the best customer service agents! He always takes care of me!
There are 20 matching cars close to your year range.






Certified
2024 Lexus RX 350 Premium Plus
Vehicle information
Features






Used
2023 Lexus RX 350 Premium
Vehicle information
Features






Used
2024 Lexus RX 350 Base
Vehicle information
Features






Used
2021 Lexus RX 350 Base
Vehicle information
Features






Certified
2020 Lexus RX 350 BASE
Vehicle information






Used
2023 Lexus RX 350 Premium Plus
Vehicle information
Features






Certified
2024 Lexus RX 350 Base
Vehicle information
Features






Certified
2024 Lexus RX 350 F SPORT Handling
Vehicle information
Features






Vehicle information
Features






Certified
2024 Lexus RX 350 F SPORT Handling
Vehicle information
Features






Certified
2023 Lexus RX 350 Premium
Vehicle information
Features






Certified
2023 Lexus RX 350 F SPORT Handling
Vehicle information
Features






Certified
2024 Lexus RX 350 Premium Plus
Vehicle information
Features






Certified
2023 Lexus RX 350 Luxury
Vehicle information
Features






Certified
2023 Lexus RX 350 Premium
Vehicle information
Features






Certified
2023 Lexus RX 350 Premium Plus
Vehicle information
Features






Certified
2024 Lexus RX 350 Premium Plus
Vehicle information
Features






Certified
2024 Lexus RX 350 Premium Plus
Vehicle information
Features






Certified
2023 Lexus RX 350 Luxury
Vehicle information
Features






Certified
2024 Lexus RX 350 Premium
Vehicle information
Features
-
Prev - 1
-
Next
Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $50,925 | 4 Good deals |
2024 Lexus RX 350 | $46,595 | 23 Good deals |
2023 Lexus RX 350 | $40,997 | 7 Good deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,131, with pricing starting at $28,592.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Lexus RX 350
Compare the 2022 Lexus RX 350
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.