Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2021 Mercedes-Benz GLS 450
for sale
near
Wheaton, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
They gave me a great price on my car.
They gave me a great price on my car. Nice honest people, very satisfactory experience overall. I like their ancient wood sculptures around the facility.
Love this car
This car met all my needs and more. Love the interior and the way its moves. So comfortable and reliable! Very pleased with this car!






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
The dealership had a great selection of quality used
The dealership had a great selection of quality used cars, all well-maintained and reasonably priced. I appreciated their transparency and honesty throughout the process, including providing detailed vehicle history reports. The financing process was also seamless, offering several options and explaining everything clearly. I left feeling confident and satisfied with my purchase. Overall, I highly recommend Affinity Auto Sales to anyone looking for a reliable used car and a pleasant buying experience. Thank you to the entire team for making this such a positive experience!
Best SUV we've ever owned.
Exceptional vehicle in the SUV class. We drove the BMW X7, Audi Q7, Volvo XC90 and this GLS 450 just kept blowing them out of the water. The ride is amazing and we feel the comfort level and size is the best






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
I recently purchased a 2020 Land Rover Range Rover and I
I recently purchased a 2020 Land Rover Range Rover and I traded in my previous vehicle . The experience was smooth and professional from start to finish . The team was excellent at staying in touch and made sure all my question were answered. Customer service was top-notch I felt valued and well taken care of throughout the process . Highly recommend.
You get what you pay for
We are in our first five months and I seriously believe all the safety options have kept me out of at least two accidents. The car on the highway practically drives itself while giving me a message. Audio systems are excellent. The 450 GLS makes driving a bit of a joy.






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
Brazil at Driven Auto of Oak Forest was AMAZING.
Brazil at Driven Auto of Oak Forest was AMAZING. He was very helpful and knowledgeable. Amir the finance manager was patient, understanding and helpful.
Great car!
Luxurious to drive and very quiet riding car. I am very satisfied with the car. The electronices are a bit over whelming at first. Love the car.






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
I found a vehicle at Nexton on Carguru.
I found a vehicle at Nexton on Carguru. Gytis was the salesman that I worked with through the entire process. Gytis was professional, responsive, accessible, patient, and accommodating to my request as I examined the vehicle. When I decided to purchase the vehicle the process went smoothly and quickly. The vehicle was transported and the driver contacted me and informed me on delivery time. When the vehicle was delivered it was all that it was sold to be. I wanted to take time and submit this review because I understand the desire that a customer has to deal with a reputable dealership. Big thanks to Nexton Motors.
Great Electronics and Engineering
This car is state of the art in human factors engineering. It has multiple layers of safety enhancements. Interior is very spacious. The 42 volt battery provides quick acceleration which allows the car to have no lag time when accelerating.






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
Great follow up, I haven't at this point found unit I was
Great follow up, I haven't at this point found unit I was pleased enough to purchase. Thanks for your attention...........done






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
Bruce Jones is the best worker of the center, he helped
Bruce Jones is the best worker of the center, he helped us to pick and get a car, he has a lot of patience. Thank you, Bruce!






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
Super impressed and happy with my 2024 BMW M3 Competition
Super impressed and happy with my 2024 BMW M3 Competition I purchased at Baha’s. The car’s beautiful, rate was awesome, and the whole experience was wonderful

Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
See Farah at Countryside Mitsubishi with the car you want
See Farah at Countryside Mitsubishi with the car you want in mind and she will not stop until she finds it!!
There are 20 matching cars close to your year range.






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz GLS 450 Base 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features


Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
-
Prev - 1
-
Next
Mercedes-Benz GLS 450 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz GLS 450 | $80,886 | 9 Great deals |
2024 Mercedes-Benz GLS 450 | $68,999 | 9 Good deals |
2023 Mercedes-Benz GLS 450 | $57,500 | 5 Great deals |
2022 Mercedes-Benz GLS 450 | $47,895 | 7 Good deals |
2017 Mercedes-Benz GLS 450 | $14,888 | 8 Good deals |
About the 2021 Mercedes-Benz GLS 450
4MATIC shown (base trim).
- Seating
- 6
- Door count
- 4
- Drivetrain
- All-wheel drive
- Combined MPG
- 21
- Transmission
- 9-Speed A/T
- Engine
- 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2021 Mercedes-Benz GLS 450 cost?
The 2021 Mercedes-Benz GLS 450 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 GLS 450 is $45,514, with pricing starting at $31,995.
What is the MPG of the 2021 Mercedes-Benz GLS 450?
The 2021 Mercedes-Benz GLS 450 offers up to 20 MPG in city driving and 24 MPG on the highway for a combined rating of 21 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz GLS 450?
The 2021 Mercedes-Benz GLS 450 compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz GLS 450 reliable?
The 2021 Mercedes-Benz GLS 450 has an average reliability rating of 3.5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 GLS 450 owners.
Is the 2021 Mercedes-Benz GLS 450 a good SUV?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz GLS 450.
- Comfort 5.0
- Interior 4.9
- Performance 3.8
- Value 3.1
- Exterior 4.9
- Reliability 3.5
62% of drivers recommend this car
- Comfort 5.0
- Interior 4.9
- Performance 3.8
- Value 3.1
- Exterior 4.9
- Reliability 3.5
GLS 450 (1 style)
Style |
---|
GLS 450 4MATIC SUV |
Inventory price |
Starting at $76,000 |
Combined MPG |
21 |
Engine |
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz GLS 450
Compare the 2021 Mercedes-Benz GLS 450
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}