Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Mercedes-Benz GLS 450
for sale
near
South Holland, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
Thank you Amy in customer care & Tony tech guy
Amy in customer care & Tony the tech guy are fantastic! I bought my car at another dealership which isn't as pleasant or great to deal with as much as Audi Of Orland.
Very happy with my purchase from RBM Alpharetta.
Very happy with my purchase from RBM Alpharetta. The car has a very comfortable interior with all the features available. Handles well in town and on long drives. Good acceleration for such a big vehicle. Love the contemporary exterior.






Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
I just bought a one year old GLE 53 Coupe from michael
I just bought a one year old GLE 53 Coupe from michael Moran and had a great experience. He was a real professional, none of the typical car dealer nonsense. Everything was very easy and they delivered the car to me one day later. Very good experience






Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
This is the third S-class Mercedes I have purchased from
This is the third S-class Mercedes I have purchased from Mercedes-Benz of Westmont and I could not be happier. Going through the purchasing process was a delight because Kimberely Cager, my Sales Rep, and the sales management team made me feel better than just a valued customer. The real test, however, came when driving the new 2025 Mercedes S580. The supreme road handling and comfortable seating were nothing short of spectacular, and the many options like the integrated toll system (driving through tolls of different states has become hassle free), Apple CarPlay, and several driver-assist features has enhanced my driving experience. While understanding how to use and benefit from the many new features and options was a little daunting, Kimberely and the Product Concierge, Damir Oliynyk, have eased my doubts, and I?m looking forward to a long multi-state road trip.



Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450
Vehicle information



Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450
Vehicle information

Used
2022 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
My experience is good but I’m looking for car is hai
My experience is good but I’m looking for car is hai price But staff is very good and great response 👍
There are 15 matching cars close to your year range.






Used
2020 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2024 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz GLS 450 Base 4MATIC
Vehicle information
Features






Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2024 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features






Used
2020 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features



Mercedes-Benz Certified
2024 Mercedes-Benz GLS 450
Vehicle information
Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
-
Prev - 1
-
Next
Mercedes-Benz GLS 450 prices by year
Model year | Prices from | Deals |
---|---|---|
2026 Mercedes-Benz GLS 450 | $93,190 | |
2025 Mercedes-Benz GLS 450 | $78,220 | 5 Good deals |
About the 2022 Mercedes-Benz GLS 450
4MATIC shown (base trim).
- Seating
- 6
- Door count
- 4
- Drivetrain
- All-wheel drive
- Combined MPG
- 20
- Transmission
- 9-Speed A/T
- Engine
- 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2022 Mercedes-Benz GLS 450 cost?
The 2022 Mercedes-Benz GLS 450 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 GLS 450 is $53,761, with pricing starting at $35,892.
What is the MPG of the 2022 Mercedes-Benz GLS 450?
The 2022 Mercedes-Benz GLS 450 offers up to 18 MPG in city driving and 24 MPG on the highway for a combined rating of 20 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Mercedes-Benz GLS 450?
The 2022 Mercedes-Benz GLS 450 compares to and/or competes against the following vehicles:
Is the 2022 Mercedes-Benz GLS 450 reliable?
The 2022 Mercedes-Benz GLS 450 has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 GLS 450 owners.
Is the 2022 Mercedes-Benz GLS 450 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz GLS 450.
- Comfort 4.0
- Interior 4.0
- Performance 3.0
- Value 3.0
- Exterior 4.5
- Reliability 3.0
50% of drivers recommend this car
- Comfort 4.0
- Interior 4.0
- Performance 3.0
- Value 3.0
- Exterior 4.5
- Reliability 3.0
GLS 450 (1 style)
Style |
---|
GLS 450 4MATIC SUV |
Inventory price |
Starting at $77,850 |
Combined MPG |
20 |
Engine |
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Similar Cars
-
BMW X7 for sale
2 Great Deals out of 20 listings starting at $41,500
Research the 2022 Mercedes-Benz GLS 450
Compare the 2022 Mercedes-Benz GLS 450
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}