Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
Est. max vehicle price based on your desired monthly budget (...% APR*. and ...% sales tax)
$...*
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
for sale
near
Laguna Beach, CA
5 matches
30 miles from 92652
Be the first to know!
Est.
$400
/mo*
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
48,177 mi.
$68,000
$500 price drop
Mercedes-Benz of Laguna Niguel (Murgado)
Vehicle information
Ext. color: Obsidian Black Metallic
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
17-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: 21156LR
VIN: W1K6G7GB2MA024277
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Keyless Entry, Keyless Start, Navigation System
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
2021 Mercedes-Benz S-Class S 580 4MATIC review
Love my Mercedes
I have been driving Mercedes Benz s class vehicles for over 10 years, traded every 3-4 years and have been very happy, always have them serviced at the dealer, always received a loaner, no complaints.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
25,345 mi.
$70,991
J Star Chrysler Dodge Jeep Ram of Anaheim Hills
Vehicle information
Ext. color: Anthracite Blue Metallic
Int. color: Macchiato/Magma Gray
Drivetrain: All-wheel Drive
MPG:
17-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: 90320T
VIN: W1K6G7GB9MA031646
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Keyless Entry, Keyless Start, Navigation System
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
J Star Chrysler Dodge Jeep Ram of Anaheim Hills review
No hassle warranty work
I have had a couple warranty-covered issues with my otherwise-wonderful 2018 Pacifica. At J-Star, there was no hassle and they even noticed another warranty-covered item and took care of it for me.
2021 Mercedes-Benz S-Class S 580 4MATIC review
An Absolute Dream
I have owned 6 S Class (SonderKlas) cars in my life and each and every single one has been problem free and a pure joy to own, drive, and admire. The 2021 S580 however.. Well this car is truly something special and not an incremental upgrade! This thing is crazy
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
19,986 mi.
$68,995
Zee Motors Inc
Vehicle information
Ext. color: designo Diamond White
Int. color: White
Drivetrain: All-wheel Drive
MPG:
17-25
Fuel type: Gasoline
Transmission: Automatic, 9-Spd 9G-Tronic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: B3599
VIN: W1K6G7GB9MA049192
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Zee Motors Inc review
My search for Toyota Sequoia used was very simple I
My search for Toyota Sequoia used was very simple I appreciate it was user friendly.
2021 Mercedes-Benz S-Class S 580 4MATIC review
Luxury
Luxury at its best, you can’t get better than that with this price range. S 580 is the way to go, the 8 cylinders are so smooth yet so sporty. This car can be Rolls Royce luxury and lamborghini urus if it wants
Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
27,011 mi.
$70,893
$1,001 price drop
Fletcher Jones Motorcars
Vehicle information
Ext. color: Black
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
17-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: N181268A
VIN: W1K6G7GB4MA037046
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Fletcher Jones Motorcars review
It was a great experience from beginning to end.
It was a great experience from beginning to end. I got exactly what I wanted and it was delivered to me in perfect condition. I can’t thank them enough.
Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
33,985 mi.
$68,895
Mercedes-Benz of Anaheim
Vehicle information
Ext. color: Black
Int. color: Black Nappa Leather
Drivetrain: All-wheel Drive
Fuel type: Hybrid
Stock #: MA052472
VIN: W1K6G7GB8MA052472
Reviews
Mercedes-Benz of Anaheim review
Every one who we talk to in the buying process was great
Every one who we talk to in the buying process was great ! Definitely will be back soon Thank you
There are 9 matching cars close to your year range.
Used
2022 Mercedes-Benz S-Class
14,194 mi.
$80,998
CarMax Buena Park
Vehicle information
Ext. color: White
Int. color: BLACK
Drivetrain: Four-wheel Drive
MPG:
16-25
Fuel type: Gasoline
Transmission: Automatic
Engine: Turbo Gas
Stock #: 27479674
VIN: W1K6G7GB6NA156542
Features
Convenience:
Navigation System
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating:
Leather Seats, Memory Seat
Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
41,644 mi.
$74,894
Fletcher Jones Motorcars
Vehicle information
Ext. color: MANUFAKTUR Diamond White
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: P54665
VIN: W1K6G7GB8NA085392
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2022 Mercedes-Benz S-Class S 580 4MATIC
53,422 mi.
$64,892
Fletcher Jones Motorcars
Vehicle information
Ext. color: Nautical Blue Metallic
Int. color: Macchiato/Magma Grey
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: P54282
VIN: W1K6G7GB0NA067100
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2022 Mercedes-Benz S-Class S 580 4MATIC
42,074 mi.
$66,333
House of Imports
Vehicle information
Ext. color: Black
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline/Mild Electric Hy
Transmission: A/T
Engine: 4.0 LITER TURBO
Stock #: NA093766
VIN: W1K6G7GB8NA093766
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
24,834 mi.
$74,933
House of Imports
Vehicle information
Ext. color: Black
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: NA156383
VIN: W1K6G7GB1NA156383
Features
Convenience:
Adaptive Cruise Control, Automatic Parking, Cooled Seats, Heated Seats, Keyless Entry, Keyless Start, Navigation System, Power Folding Mirrors, Power Liftgate
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, Satellite Radio, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Mercedes-Benz Certified
2023 Mercedes-Benz S-Class S 580 4MATIC
25,349 mi.
$93,894
Fletcher Jones Motorcars
Vehicle information
Ext. color: MANUFAKTUR Diamond White
Int. color: Carmine Red/Black
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: S009919B
VIN: W1K6G7GB2PA189184
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
19,660 mi.
$83,894
Fletcher Jones Motorcars
Vehicle information
Ext. color: MANUFAKTUR Diamond White
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: P54642
VIN: W1K6G7GB2NA073254
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
No photo available
Used
2023 Mercedes-Benz S-Class S 580 4MATIC
16,762 mi.
$94,894
Fletcher Jones Motorcars
Vehicle information
Ext. color: MANUFAKTUR China Blue Solid
Int. color: Sienna Brown/Black
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: N183930A
VIN: W1K6G7GB6PA204804
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2023 Mercedes-Benz S-Class S 580 4MATIC
12,992 mi.
$89,995
House of Imports
Vehicle information
Ext. color: Graphite Grey
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
16-25
Fuel type: Gasoline/Mild Electric Hy
Transmission: A/T
Engine: 4.0L 8 CYL
Stock #: PA181327
VIN: W1K6G7GB2PA181327
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
-
Prev - 1
-
Next
Mercedes-Benz S-Class prices by year
| Model year | Prices from | Deals |
|---|---|---|
| 2025 Mercedes-Benz S-Class S 580 4MATIC | $118,881 | 1 Good deal |
About the 2021 Mercedes-Benz S-Class S 580 4MATIC
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)
How much does the 2021 Mercedes-Benz S-Class S 580 4MATIC cost?
The 2021 Mercedes-Benz S-Class S 580 4MATIC price depends on several factors, including optional features, mileage, vehicle history and location. The nationwide average price for a 2021 S-Class S 580 4MATIC is $72,856, with pricing starting at $48,549.
What is the MPG of the 2021 Mercedes-Benz S-Class S 580 4MATIC?
The 2021 Mercedes-Benz S-Class S 580 4MATIC offers up to 16 MPG in city driving and 26 MPG on the highway for a combined rating of 20 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle options, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz S-Class S 580 4MATIC?
The 2021 Mercedes-Benz S-Class S 580 4MATIC compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz S-Class S 580 4MATIC reliable?
The 2021 Mercedes-Benz S-Class has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 S-Class owners.
Is the 2021 Mercedes-Benz S-Class S 580 4MATIC a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz S-Class.
Rating breakdown (out of 5):
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
100% of drivers recommend this car
Rating breakdown (out of 5):
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
5 matches
Clear
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_name}
${award_two_name ? `
${award_blurb}
${award_two_name}
` : ``}
${award_two_blurb}