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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2022 Mercedes-Benz S-Class
for sale
near
La Grange, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
MBZ S-class always 5 ***** vehicle.
MBZ S-class always 5 ***** vehicle. The most luxurious , comfortable, car I ever drove . I highly recommend it . My old Mercedes S-class has 200,000 miles and not a single problem.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
A Wonderful Overall Experience
I just picked up my S580 Lux-Line in Emerald Green over Sienna Brown, and I am absolutely thrilled with the purchase. I have owned five S-Class models since 2010, including this new one, and I can say this is the best iteration yet from an overall perspective. While I still think the W222 was the best-looking (especially my 2019 S560 with the refreshed look and AMG pack), this new one does not disappoint at all. The Emerald Green is stunning in the sunlight, my favorite color yet. And the interior is on another level from a luxury and tech standpoint. I loved the interiors of all the S-Class models I've owned, but this current one is my favorite. The seats are super supportive, and the vast amount of tech is amazing. The new infotainment screen takes time to learn and get used to, but I feel the "Hey, Mercedes" function makes doing small things like putting in a Navigation request easier than going through the main screen. From a driving perspective, the ride is the best yet, just like gliding on a cloud. I've been lucky to have driven Bentley's and Rolls-Royce's in my lifetime, and this ride is as close as I've seen the S-Class come to being even with those vehicles on this front. And, the V8 is plenty punchy when needed, so it can be a fun vehicle to take on windy roads if you so desire. Overall, a wonderful vehicle and a bargain when you compare it to the other super-luxury vehicles on sale. I'm looking forward to the next few years of owning such an awesome car.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Armin was amazing to work with, went above and beyond in
Armin was amazing to work with, went above and beyond in more ways than one, to ensure we had a pleasant experience. We brought the car while in Colorado, having it shipped. Was exactly we expected. Highly recommend!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Best place for a Range Rover
Came in from Wisconsin to check out a Range Rover and I’ve never been so impressed. The car was in perfect condition, I received fantastic service and I was in and out very quick. Highly recommend






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
The dealership had a great selection of quality used
The dealership had a great selection of quality used cars, all well-maintained and reasonably priced. I appreciated their transparency and honesty throughout the process, including providing detailed vehicle history reports. The financing process was also seamless, offering several options and explaining everything clearly. I left feeling confident and satisfied with my purchase. Overall, I highly recommend Affinity Auto Sales to anyone looking for a reliable used car and a pleasant buying experience. Thank you to the entire team for making this such a positive experience!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Top-notch dealership for specialty vehicles!
Outstanding dealership!! They have a meticulously selected inventory of phenomenal luxury, classic and high-end vehicles at great prices. After searching for months, I was fortunate to find a muscle car gem at Platinum Motorsports – a very low-mile 2001 Camaro SS 6-speed in excellent condition for being 20+ years old! The guys there are all top-notch in the business; they genuinely care about their clients and are not just in it to make a quick sale. Manny, Zico and Rick have high integrity, are very communicative and helpful, and went above and beyond to get my new ride shipped to me promptly (even in the middle of a Chicago blizzard!) I can't say enough good things about the crew there, and I enthusiastically recommend them. If you’re thinking of buying one of the outstanding vehicles you see on their site, do it – you won’t regret it!!






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Staff were all kind helpful and very professional The
Staff were all kind helpful and very professional The staff allowed me time to look at a car. Price was very competitive






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Sales rep (Kenn) and GM (Bradley) were awesome to work
Sales rep (Kenn) and GM (Bradley) were awesome to work with. Just the kind of buying experience everyone is looking for. Highly recommended!






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Steve was an excellent sales rep.
Steve was an excellent sales rep. Ultimo has a great stable of cars to select from. Steve went out of his way to help me with my trade in, new summer wheels & tires and answered all of my questions accurately.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
THE LUXURY EXPERIENCE
I made an appointment on line. When I arrived they had a loaner full of gas waiting for me. Then when I picked up my Bentley it looked brand new again. That is what I call "THE LUXURY EXPERIENCE !!!!!!!!"






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I was skeptical about purchasing a car from a used car
I was skeptical about purchasing a car from a used car dealer however in having very good experience in purchasing a new BMW from Perillo BMW many years ago the Perillo name provided me some comfort. Perillo Downers Grove delivered upon my expectation’s in purchasing a lightly used BMW 750i






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Excellent
Mark made my experience the best! Quick simple and easy. No run arounds. Will be returning again the In the future he is the best!



Mercedes-Benz Certified
2022 Mercedes-Benz S-Class
Vehicle information






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Motor Cars of Chicago is a great dealership to work with!
Motor Cars of Chicago is a great dealership to work with! I purchased a used Dodge 3500 there and was provided a wonderful experience from the moment I walked in the door. Mark assisted me through the process and was helpful and very pleasant to work with! Highly recommend Mark AND this dealership!






Mercedes-Benz Certified
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Great service as always.
Great service as always. Really liked Francisco. He was very personable and extremely helpful. Very easy to work with. And that's all I have to say.






Used
2022 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
We stopped into Mercedes of Westmont as a second stop in
We stopped into Mercedes of Westmont as a second stop in our search for a new car. I am not really a fan of buying new cars, we typically buy a car and drive it until it’s dead, just so we don’t have to go thru the whole purchasing process of getting a new car. Chris at Mercedes of Westmont has completely changed my outlook on buying new cars! He is very professional, but yet relatable and understanding of the process and how to make it a pleasurable experience. We weren’t looking to purchase a car that day, but Chris really listened to our wants and needs and was able to find something for us that fit what we were looking for. He was very patient with us as we made our decision. Hands down the best experience I’ve had buying a car.






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Chris and Matt are all world!
Chris and Matt are all world! Love my car and our entire experience buying from them. Very responsive and dependable. Knowledgeable as well. Joey






Used
2022 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
We actually traveled four hours to this Chicago used car
We actually traveled four hours to this Chicago used car dealership that listed a lot of used model X's, drove a couple, then found out that they will personally inspect a car and give us a high-quality video walk around and deliver to us for $350 [chicago to 49417]. Nader was very helpful and patient. So we went home and kept checking online until that dealership listed the car with all the options we wanted, then got videos via txt, called back and asked some basic questions, then bought and had it delivered. They also helped us navigate the intricacies of an interstate purchase. We also learned that model X's move quickly, Driven Auto dozens of cars per week if not more, so when you see it you better pull the trigger quickly
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Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $114,990 | 1 Good deal |
2024 Mercedes-Benz S-Class | $84,999 | 7 Good deals |
2023 Mercedes-Benz S-Class | $63,985 | 6 Good deals |
2018 Mercedes-Benz S-Class | $27,980 | 4 Good deals |
2015 Mercedes-Benz S-Class | $15,998 | 7 Great deals |
About the 2022 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2022 Mercedes-Benz S-Class cost?
The 2022 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 S-Class is $71,847, with pricing starting at $50,595.
What is the MPG of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class offers up to 21 MPG in city driving and 30 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Mercedes-Benz S-Class?
The 2022 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2022 Mercedes-Benz S-Class reliable?
The 2022 Mercedes-Benz S-Class has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 S-Class owners.
Is the 2022 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
50% of drivers recommend this car
- Comfort 5.0
- Interior 4.0
- Performance 4.5
- Value 3.5
- Exterior 4.2
- Reliability 3.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $111,100 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $117,700 |
Combined MPG |
19 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Mercedes-Benz S-Class
Compare the 2022 Mercedes-Benz S-Class
2022 Mercedes-Benz S-Class by city
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2022 Mercedes-Benz S-Class in La Grange, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Western Springs, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in La Grange Park, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Brookfield, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Countryside, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Hinsdale, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Lyons, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Indian Head Park, IL
7 Great Deals out of 29 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Hodgkins, IL
7 Great Deals out of 29 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Westchester, IL
7 Great Deals out of 31 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Summit, IL
7 Great Deals out of 30 listings starting at $54,991
-
2022 Mercedes-Benz S-Class in Riverside, IL
7 Great Deals out of 30 listings starting at $54,991
Mercedes-Benz S-Class trims
-
Mercedes-Benz S-Class 2022 S 580 4MATIC
5 Great Deals out of 24 listings starting at $54,991
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