• (4.3) 46 reviews
  • MSRP: $3,435–$13,251
  • Body Style: Sedan
  • Combined MPG: 18-32
  • Engine: 201-hp, 3.2-liter I-6 (diesel)
  • Drivetrain: Rear-wheel Drive
  • Transmission: 5-speed automatic w/OD and auto-manual
2006 Mercedes-Benz E-Class

Our Take on the Latest Model 2006 Mercedes-Benz E-Class

What We Don't Like

  • Complicated, nonintuitive controls
  • Price
  • Fuel economy of E55 AMG

Notable Features

  • Variety of engine choices
  • Available seven-speed automatic
  • RWD or AWD
  • Sedan and wagon body styles
  • E320 CDI diesel sedan
  • E350 replaces E320 for 2006

2006 Mercedes-Benz E-Class Reviews

Vehicle Overview
Mercedes-Benz introduced a new generation of its midsize E-Class sedan for 2003. A 221-horsepower, 3.2-liter V-6 powered the E320, while the E500 got a 302-hp V-8.

A high-performance E55 AMG model with a 469-hp supercharged V-8 is also available. A wagon body style is offered, and E-Class models can be equipped with rear-wheel drive or 4Matic all-wheel drive. The E-Class is slotted between the German automaker's smaller C-Class and top-rung S-Class.

Sport versions of the sedan and wagon are available, and rear-drive E500 models gained a seven-speed-automatic transmission for 2004. Bi-xenon active headlights are available.

For the 2006 model year, a new E350 series with a 268-hp, 3.5-liter V-6 replaces the E320. Active front head restraints are newly standard. New 17-inch wheels are installed on E350 and E500 models.

Mercedes-Benz added an E320 CDI sedan with a diesel engine for 2005.
(Skip to details on the: E320 CDI)

Moved to a new platform for 2003, the E-Class sedan displays more flowing lines than its predecessor and sports a lower, swept-back front end. Oval headlights are angled back more sharply, and a sculpted trunk replaced the former squared-off profile. The front fenders, hood, trunk lid and bolted-on frame members are made of aluminum.

An Airmatic air suspension is standard on the E500 and E55 AMG and optional on the E350. An AMG Sport Package for the E350 and E500 includes sculpted front and rear aprons and staggered-width 18-inch wheels. An Appearance Package for the E350 and E500 includes sculpted side skirts and active-curve headlights.

Front-seat occupants in the five-passenger interior face a V-shaped console. Standard equipment includes a power tilt/telescoping steering wheel and Mercedes' COMAND instrument panel system. A navigation system is optional. Four-zone automatic climate control goes into the E500.

Under the Hood
The new E350 gets a 268-hp, 3.5-liter V-6, while the E500 packs a 5.0-liter V-8 that cranks out 302 hp and 339 pounds-feet of torque. The supercharged 5.5-liter V-8 in E55 AMG models delivers 469 hp and 516 pounds-feet of torque. In the E320 CDI sedan, a 3.2-liter inline-six-cylinder diesel produces 201 hp and 369 pounds-feet of torque. The rear-drive E350 and E500 use a seven-speed-automatic transmission, but other models have a five-speed automatic.

Sensotronic brake control, which is a brake-by-wire system, promises faster, more surefooted emergency response. Antilock brakes and Mercedes-Benz's Electronic Stability Program are standard. Adaptive front airbags deploy at a lower force in less-severe collisions. Side-impact and side curtain-type airbags are standard.

Driving Impressions
Civility reigns behind the wheel of the E-Class. Everything about this car is smooth and luxurious.

The redesigned 2003 E-Class lost most of the heavy feel that was unpleasantly noticeable on previous models. The refined E500 delivers lively acceleration whether it's starting from a standstill, passing or merging. Trimmed in beautiful wood, the dashboard layout is a little too complicated for some people, and the tachometer should be a bit larger.

Consumers seeking stunning four-door performance need not search any further than the E55 AMG, which responds to the throttle like a supercar and has taut handling to match. Few cars of this caliber are so satisfying overall.

E320 CDI
After a five-year absence, diesel power returned to a Mercedes-Benz model sold in the U.S. for 2005. Americans have shunned diesels, citing such drawbacks as noise and odors.

With the E320 CDI sedan, Mercedes-Benz claimed to have overcome those negative factors, though emissions remain an obstacle until improved diesel fuel emerges. The E320 CDI meets the emissions requirements of 45 states.

Mercedes-Benz claims the turbocharged E320 CDI can accelerate from zero to 60 mph in 6.6 seconds — slightly faster than the gasoline-powered E320 — yet it earns an Environmental Protection Agency-estimated 27 mpg in city driving and 37 mpg on the highway. Except for the lack of optional Sport and Appearance packages, the E320 CDI's equipment is the same as its gasoline-powered E-Class siblings.

Not only does the diesel engine start normally in the E320 CDI, but it's also difficult to discern that you're riding in a diesel-powered sedan. A slight engine rattle might be heard occasionally, but the car is generally quiet. Acceleration is smooth and effortless, if less dramatic than in a gasoline-powered automobile. No odors are evident. You can expect more than 30 mpg on the highway. Approaching the 37-mpg estimate demands a gentle throttle foot and careful attention to traffic flow. Back to top

Consumer Reviews


Average based on 46 reviews

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Mercedes E350

by Kumar from Red Wing, MN on October 31, 2017

I drove from Sacramento CA to Brooklyn Park MN almost non stop without any problem. So smooth that you never feel as if you r not sitting in the car. Still own it and touch wood still running very smo... Read Full Review

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10 Trims Available

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Wondering which configuration is right for you?
Our 2006 Mercedes-Benz E-Class trim comparison will help you decide.

2006 Mercedes-Benz E-Class Safety Ratings

Crash-Test Reports


There is currently 1 recall for this car.

Safety defects and recalls are relatively common. Stay informed and know what to do ahead of time.

Safety defects and recalls explained

Service & Repair

Estimated Service & Repair cost: $4,400 per year.

Save on maintenance costs and do your own repairs.

Warranty Coverage

What you should get in your warranty can be confusing. Make sure you are informed.

Learn More About Warranties

Warranties Explained


Often called a basic warranty or new-vehicle warranty, a bumper-to-bumper policy covers components like air conditioning, audio systems, vehicle sensors, fuel systems and major electrical components. Most policies exclude regular maintenance like fluid top offs and oil changes, but a few brands have separate free-maintenance provisions, and those that do offer them is slowly rising. Bumper-to-bumper warranties typically expire faster than powertrain warranties.


Don't be misled a 10-year or 100,000-mile powertrain warranty doesn't promise a decade of free repairs for your car. It typically covers just the engine and transmission, along with any other moving parts that lead to the wheels, like the driveshaft and constant velocity joints. Some automakers also bundle seat belts and airbags into their powertrain warranties. With a few exceptions, powertrain warranties don't cover regular maintenance like engine tuneups and tire rotations.

Roadside Assistance

Some automakers include roadside assistance with their bumper-to-bumper or powertrain warranties, while others have separate policies. These programs cover anything from flat-tire changes and locksmith services to jump-starts and towing. Few reimburse incidental costs like motel rooms (if you have to wait for repairs).

Free Scheduled Maintenance

Some automakers include free scheduled maintenance for items such as oil changes, air filters and tire rotations. Some include consumables including brake pads and windshield wipers; others do not. They are typically for the first couple of years of ownership of a new car.

Other Years