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Mercedes-Benz E-Class

5/5 Safety rating
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$38,317
Avg. listing price
Shop the 2022 Mercedes-Benz E-Class
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Available trims

See the differences side-by-side to compare trims.
  • E 350 RWD Sedan
    Avg. price
    $34,108
    MPG
    23 City / 31 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Premium Gasoline I-4
    Drivetrain
    Rear Wheel Drive
    Shop this trim See all specs
  • E 350 4MATIC Sedan
    Avg. price
    $35,698
    MPG
    21 City / 29 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Premium Gasoline I-4
    Drivetrain
    All Wheel Drive
    Shop this trim See all specs
  • E 450 4MATIC Sedan
    Avg. price
    $44,772
    MPG
    23 City / 30 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    All Wheel Drive
    Shop this trim See all specs
  • E 450 RWD Coupe
    Avg. price
    $44,772
    MPG
    22 City / 29 Hwy
    Seat capacity
    4
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    Rear Wheel Drive
    Shop this trim See all specs
  • E 450 4MATIC All-Terrain Wagon
    Avg. price
    $44,772
    MPG
    21 City / 28 Hwy
    Seat capacity
    7
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    All Wheel Drive
    Shop this trim See all specs
  • E 450 4MATIC Coupe
    Avg. price
    $44,772
    MPG
    21 City / 30 Hwy
    Seat capacity
    4
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    All Wheel Drive
    Shop this trim See all specs
  • E 450 RWD Cabriolet
    Avg. price
    $44,772
    MPG
    22 City / 29 Hwy
    Seat capacity
    4
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    Rear Wheel Drive
    Shop this trim See all specs
  • E 450 4MATIC Cabriolet
    Avg. price
    $44,772
    MPG
    22 City / 29 Hwy
    Seat capacity
    4
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    All Wheel Drive
    Shop this trim See all specs

The good & the bad

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Safety review

Based on the 2022 Mercedes-Benz E-Class base trim
NHTSA crash test and rollover ratings, scored out of 5.
Overall rating
Combined side rating front seat
Combined side rating rear seat
Frontal barrier crash rating driver
Frontal barrier crash rating passenger
Overall frontal barrier crash rating
Overall side crash rating
Rollover rating
Side barrier rating
Side barrier rating driver
Side barrier rating passenger rear seat
Side pole rating driver front seat
9.7%
Risk of rollover
Side barrier rating driver
Side barrier rating passenger rear seat
Side pole rating driver front seat
9.7%
Risk of rollover

Factory warranties

New car program benefits

Basic
4 years / 50,000 miles
Corrosion
4 years / 50,000 miles
Powertrain
4 years / 50,000 miles
Roadside Assistance
4 years / 50,000 miles

Certified Pre-Owned program benefits

Age / mileage
6 years old or less / less than 75,000 miles
Basic
1 year / unlimited miles
Dealer certification
164-point inspection
See all CPO program details

Compare similar vehicles

Select cars to compare for more detailed info.
  • 2022
    3.3
    Mercedes-Benz E-Class
    Starts at
    $54,950
    2022 Mercedes-Benz E-Class
    MPG
    23 City / 31 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Premium Gasoline I-4
    Drivetrain
    Rear-wheel drive
    Compare
  • 2021
    4.0
    Mercedes-Benz AMG E 53
    Starts at
    $73,900
    2021 Mercedes-Benz AMG E 53
    MPG
    22 City / 29 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    All-wheel drive
    Compare
  • 2022
    4.5
    BMW 540
    Starts at
    $59,950
    2022 BMW 540
    MPG
    25 City / 32 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    Rear-wheel drive
    Compare
  • 2021
    5.0
    BMW 530
    Starts at
    $54,200
    2021 BMW 530
    MPG
    25 City / 33 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Premium Gasoline I-4
    Drivetrain
    Rear-wheel drive
    Compare
  • 2023
    4.0
    Mercedes-Benz E-Class
    Starts at
    $56,750
    2023 Mercedes-Benz E-Class
    MPG
    23 City / 31 Hwy
    Seat capacity
    5
    Engine
    Intercooled Turbo Gas/Electric I-6
    Drivetrain
    Rear-wheel drive
    Compare
  • Compare more options
    Use our comparison tool to add any vehicle of your choice and see a full list of specifications and features side-by-side.
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Consumer reviews

66% of drivers recommend this car
Based on 3 reviews
Write a review
Comfort
3.7
Interior
3.3
Performance
4.3
Value
4.0
Exterior
4.0
Reliability
3.3

Most recent

  • By Skibum3087 from Boulder, CO
    Owns this car
    April 30, 2025

    Worst car I’ve ever had.

    Worst car I’ve ever had. Has spent over 160 days in service at Mercedes dealers for various issues ranging from mechanical to software related failures and tons of build quality issues and rattles. Have been to 5 separate Mercedes dealers for service, all but one are terrible and require multiple trips to resolve the same issue. My AC was making clunking noises and required 7 service visits at 3 separate dealers before the 3rd dealer finally acknowledged the problem and fixed it. The rear shocks failed, the pump for the air suspension failed, the parking module failed, the front axle seal failed, the camera system stopped working and software had to be updated. The parktronic software also failed and had to be updated. The heads up display failed. Tons of other issues. 4 of the 5 Mercedes dealers have been terrible to work with and had no clue what they were doing. The 5th is excellent but it’s clear Mercedes doesn’t take quality seriously, and they don’t train their dealers well. The car is also a rattle box. The headliner was rattling and when I brought it for service they told me the factory forgot to put one of the clips in
    • Purchased a Used car
    • Used for Transporting family
    • Does not recommend this car
    Comfort
    3.0
    Interior
    2.0
    Performance
    4.0
    Value
    3.0
    Exterior
    3.0
    Reliability
    1.0
    7 people out of 8 found this review helpful. Did you?
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  • By Moe from TX dallas
    Owns this car
    July 12, 2023

    Looks amazing

    So nice car so fast so much options and futuristic it’s future world of cars performance, AMG I would recommend it for smart people it’s great
    • Purchased a Used car
    • Used for Having fun
    • Does recommend this car
    Comfort
    5.0
    Interior
    5.0
    Performance
    5.0
    Value
    5.0
    Exterior
    5.0
    Reliability
    5.0
    2 people out of 4 found this review helpful. Did you?
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  • By Mike from Revere, Ma
    Owns this car
    January 2, 2023

    The Most Impressive Mercedes Yet !

    The confidence you feel driving a Mercedes’ is unmatched, unfortunately there are few discrepancies ..The seats are too confining, you can’t squirm or move in any direction. I think these movements are necessary for long term driving.A lot of the options the car has are complicated to use and some even unnecessary. As for the handling, braking, response time is excellent! my sixth Mercedes, but it’s my first new One!! The overall experience thus far has been Great !! Bravo Mercedes!
    • Purchased a New car
    • Used for Commuting
    • Does recommend this car
    Comfort
    3.0
    Interior
    3.0
    Performance
    4.0
    Value
    4.0
    Exterior
    4.0
    Reliability
    4.0
    12 people out of 17 found this review helpful. Did you?
    Yes No
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FAQ

What trim levels are available for the 2022 Mercedes-Benz E-Class?

The 2022 Mercedes-Benz E-Class is available in 2 trim levels:

  • E 350 (2 styles)
  • E 450 (6 styles)

What is the MPG of the 2022 Mercedes-Benz E-Class?

The 2022 Mercedes-Benz E-Class offers up to 23 MPG in city driving and 31 MPG on the highway. These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on vehicle options, trim level, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Mercedes-Benz E-Class?

The 2022 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:

Is the 2022 Mercedes-Benz E-Class reliable?

The 2022 Mercedes-Benz E-Class has an average reliability rating of 3.3 out of 5 according to cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 Mercedes-Benz E-Class owners.

Is the 2022 Mercedes-Benz E-Class a good Sedan?

Below are the cars.com consumers ratings for the 2022 Mercedes-Benz E-Class. 66.7% of drivers recommend this vehicle.

3.3 / 5
Based on 3 reviews
  • Comfort: 3.7
  • Interior: 3.3
  • Performance: 4.3
  • Value: 4.0
  • Exterior: 4.0
  • Reliability: 3.3

Mercedes-Benz E-Class history

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