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Used
2021 Lexus IS 350 sedans
for sale
near me
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.




Used
2021 Lexus IS 350 Base
Vehicle information
Features
Reviews
Chesrown has done it again, was provided excellent,
Chesrown has done it again, was provided excellent, courteous, and prompt service! Greeted by my Advisor from arrival, guided through the process to departure. It took me 45 minutes to drive to the dealership, service took less than 20 minutes?.as usual. I love this dealership!
Great car but we've only owned it for 3 weeks
We are so happy we bought this car - it is more than we had hoped for and it is actually more appealing than we had anticipated
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Used
2021 Lexus IS 350 Base
Vehicle information
Features






Used
2021 Lexus IS 350 Base
Vehicle information
Features






Used
2021 Lexus IS 350 Base
Vehicle information
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Used
2021 Lexus IS 350 Base
Vehicle information
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Used
2021 Lexus IS 350 F Sport
Vehicle information
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Used
2021 Lexus IS 350 Base
Vehicle information
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Used
2021 Lexus IS 350 Base
Vehicle information
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Used
2021 Lexus IS 350 Base
Vehicle information
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Used
2021 Lexus IS 350 Base
Vehicle information
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Used
2021 Lexus IS 350 Base
Vehicle information
Features
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Lexus IS 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus IS 350 | $42,397 | 22 Great deals |
2024 Lexus IS 350 | $38,595 | 14 Great deals |
2023 Lexus IS 350 | $34,780 | 9 Great deals |
2022 Lexus IS 350 | $28,595 | 87 Good deals |
2020 Lexus IS 350 | $24,900 | 14 Good deals |
2018 Lexus IS 350 | $20,444 | 5 Good deals |
2016 Lexus IS 350 | $12,795 | 10 Good deals |
About the 2021 Lexus IS 350
F Sport shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2021 Lexus IS 350 cost?
The 2021 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 IS 350 is $36,619, with pricing starting at $27,998.
What is the MPG of the 2021 Lexus IS 350?
The 2021 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
Is the 2021 Lexus IS 350 reliable?
The 2021 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 IS 350 owners.
Is the 2021 Lexus IS 350 a good sedan?
Below are the Cars.com consumer ratings for the 2021 Lexus IS 350.
- Comfort 5.0
- Interior 4.5
- Performance 5.0
- Value 4.5
- Exterior 5.0
- Reliability 5.0
100% of drivers recommend this car
- Comfort 5.0
- Interior 4.5
- Performance 5.0
- Value 4.5
- Exterior 5.0
- Reliability 5.0
IS 350 F SPORT (2 styles)
Style | |
---|---|
IS 350 F SPORT RWD | IS 350 F SPORT AWD |
Inventory price | |
Starting at $42,950 | Starting at $44,950 |
Combined MPG | |
23 | 22 |
Engine | |
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Lexus IS 350
Compare the 2021 Lexus IS 350
Lexus IS 350 trims
-
Lexus IS 350 2021 Base
71 listings starting at $27,998
-
Lexus IS 350 2021 F Sport
1 Great Deal out of 23 listings starting at $29,999
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