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Used
2021 Mercedes-Benz CLS 450 4MATIC
for sale
near me
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Mercedes-Benz Certified
2021 Mercedes-Benz CLS 450 CLS 450
Vehicle information
Features
Reviews
Apparently I am not computer literate.
Apparently I am not computer literate. This is my fourth and final attempt to write a review for the absolute best Mercedes dealership ever! I have had, I believe, seven Mercedes, only deviating once as I was enamored with a San Remo green convertible elsewhere. Six months later I returned to Mercedes where Deb found a lovely black GLC 300 for me, Norma and Manny aided in my lack of computer skills with the technical side of the vehicle and dear Sam watched my beloved Kingston when I did the paperwork. Service solved a software issue in a timely fashion even vacuuming my car per my request. Greg in Service was inundated with phone calls and kindly took the time to tie my shoe, again upon my request, as I was holding my multipoo. Lee Ghesquiere, his sons, Taylor and Chase are all a tribute to their late father and grandfather who has always helped me in the past and would be so proud of the legacy he founded. Thanks to all! Ruth Grimaldi Birmingham, Michigan
Looks great, drives better!
The car has all the bells and whistles and is a lot more comfortable and quiet than the E-Class we had. The engine is more powerful and we love the design.






Mercedes-Benz Certified
2021 Mercedes-Benz CLS 450 Base 4MATIC
Vehicle information
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Reviews
Just bought a nice used Maxima here this weekend.
Just bought a nice used Maxima here this weekend. I will have to say that Brandon Comer (sales) and Javier Escobar (finance) were a pleasure to deal with. Such down to earth personalities, friendly, sincere, and helpful. I actually identified a vibration / wheel issue with this vehicle during the test drive. They did not hesitate to address the issue fully and we were able to finalize the deal in a couple of days. Other that that small hiccup, the dealwas so simple and painless. My wife and I would definitely consider buying from this dealership again. It is a beautiful establishment and everyone we came in contact with were so nice and thoughtful.
Very Comfortable and Reliable car
Great design and features. Smooth ride. Love the color and safety features of the vehicle. voice recognition, touch screen dash board truly amazing too. I love it






Used
2021 Mercedes-Benz CLS 450 Base 4MATIC
Vehicle information
Features
Reviews
I bought two vehicles from them and they are awesome to
I bought two vehicles from them and they are awesome to work with. Service department always delivers. Communication is never a problem. Would totally recommend this dealership.






Mercedes-Benz Certified
2021 Mercedes-Benz CLS 450 Base 4MATIC
Vehicle information
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Reviews
The best salesman
Giovanni is one of the best salesman that I have ever met he does a great job ..I bought about four cars off of Him he does great service. And gets the deal done. ….
There are 20 matching cars close to your year range.






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2022 Mercedes-Benz CLS 450 Base 4MATIC
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2023 Mercedes-Benz CLS 450 Base
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2022 Mercedes-Benz CLS 450 Base 4MATIC
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2022 Mercedes-Benz CLS 450 Base 4MATIC
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Mercedes-Benz Certified
2023 Mercedes-Benz CLS 450 Base
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2023 Mercedes-Benz CLS 450 Base
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Mercedes-Benz Certified
2022 Mercedes-Benz CLS 450 Base
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2022 Mercedes-Benz CLS 450 Base 4MATIC
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Used
2023 Mercedes-Benz CLS 450 Base
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Used
2022 Mercedes-Benz CLS 450 Base
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Mercedes-Benz CLS 450 prices by year
Model year | Average price | Deals |
---|---|---|
2023 Mercedes-Benz CLS 450 4MATIC | $58,520 | 12 Good deals |
2022 Mercedes-Benz CLS 450 4MATIC | $47,400 | 15 Great deals |
About the 2021 Mercedes-Benz CLS 450 4MATIC
4MATIC shown.
- Seating
- 5
- Door count
- 4
- Drivetrain
- All Wheel Drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2021 Mercedes-Benz CLS 450 4MATIC cost?
The 2021 Mercedes-Benz CLS 450 4MATIC price depends on several factors, including optional features, mileage, vehicle history and location. The nationwide average price for a 2021 CLS 450 4MATIC is $38,900, with pricing starting at $38,900.
What is the MPG of the 2021 Mercedes-Benz CLS 450 4MATIC?
The 2021 Mercedes-Benz CLS 450 4MATIC offers up to 22 MPG in city driving and 29 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle options, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz CLS 450 4MATIC?
The 2021 Mercedes-Benz CLS 450 4MATIC compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz CLS 450 4MATIC reliable?
The 2021 Mercedes-Benz CLS 450 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 CLS 450 owners.
66% of drivers recommend this car
- Comfort 4.0
- Interior 4.3
- Performance 5.0
- Value 4.0
- Exterior 5.0
- Reliability 5.0
CLS 450 (1 style)
Style |
---|
CLS 450 4MATIC Coupe |
Inventory price |
Starting at $72,800 |
Combined MPG |
25 |
Engine |
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Mercedes-Benz CLS 450 trims
-
Mercedes-Benz CLS 450 2021 Base
27 listings starting at $30,000
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.