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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class
for sale
near
Burr Ridge, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz E-Class E 350 4MATIC
Vehicle information
Features
Reviews
Excellent Car with Comfort, Style, and Outstanding
Excellent Car with Comfort, Style, and Outstanding Service I recently purchased a 2016 Honda Accord EX-L, and I couldn’t be happier with my decision. Not only is the car fantastic, but the buying experience was smooth and enjoyable, thanks to Elman, the salesperson who assisted me. The car itself is a perfect blend of performance, comfort, and style. The 2.4L engine delivers smooth acceleration with excellent fuel efficiency, making it ideal for both city commutes and highway trips. The CVT transmission ensures a seamless and comfortable driving experience. Inside the cabin, the premium feel stands out. The leather seats are not only luxurious but also extremely comfortable, especially with the heated feature. The dual-zone climate control is a thoughtful addition that allows for personalized comfort. The technology package is impressive for a 2016 model. I love the touchscreen infotainment system, Apple CarPlay, and Android Auto for seamless connectivity. The advanced safety features, like lane-keeping assist and adaptive cruise control, provide added peace of mind on every drive. As for the exterior, the sleek, timeless design of the Accord EX-L is a head-turner. The LED daytime running lights and stylish alloy wheels enhance its sporty yet sophisticated appearance. I also want to give a big shoutout to Elman, who made the buying process truly enjoyable. He was professional, knowledgeable, and patient throughout. He took the time to answer all my questions, explain the features, and ensure I was confident in my purchase. It’s rare to find such excellent customer service, and Elman went above and beyond to make sure I had a great experience. Overall, I’m thrilled with my 2016 Honda Accord EX-L and highly recommend both the car and working with Elman if you’re in the market for a vehicle.
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰






Used
2021 Mercedes-Benz E-Class
Vehicle information
Features
Reviews
Price listed is the price you pay!
Dealt with this CarMax dealer over the phone and email. Tried to negotiate a price based on other dealers in the area for the same vehicle and was told that the price listed was the price you pay!
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.






Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
2017 Mercedes benz c43 amg coupe
I didn’t end up buying the car because i didn’t make my decision fast enough. It was sold. But the service was consistent and precise with emails and speedy quick at responding. Loved the service and would definitely recommend this dealer.
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.






Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
Thijis was great when I got my new Macan, and Camden has
Thijis was great when I got my new Macan, and Camden has always taken me with my last one! I am sure he will again! Great store!
This car is why you buy a Mercedes-Benz.
I'm replacing a 17 y/o E-320 that I loved. I am now infatuated with the New 2021 E-450 4 matic it just so happens to be the Motor Trend car of the year. Very nice exterior styling. Fantastic interior. all the latest technology and a great interior. The strait V-6 with turbo is smooth as silk. The optional Air Body control suspension makes for a fantastic smooth ride.






Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
Great follow up, I haven't at this point found unit I was
Great follow up, I haven't at this point found unit I was pleased enough to purchase. Thanks for your attention...........done
Love my Car
The vehicle meets all of my needs. I special ordered the vehicle with the color and leather interior I prefer. It arrived exactly the way I wanted.






Used
2021 Mercedes-Benz E-Class E 350 4MATIC
Vehicle information
Features
Reviews
We purchased a 2024 Corvette spur of the moment.
We purchased a 2024 Corvette spur of the moment. (No regrets!) From the moment I walked in, I was immediately taken care of. Kim was amazing from start to finish- she was sweet / funny! The process did not take as along as we would at any other dealer. I would definitely be coming back for any other purchases we may need in the future!






Used
2021 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
Features
Reviews
Highly recommended!
Highly recommended! it was an easy process from start to finish, the car was as advertise clean Carfax quality people they LOVE what they do - and it shows. it was a great experience from A to Z.






Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
Exceptional customer service and super understanding.
Exceptional customer service and super understanding. No beating and haggling straight to the point. In and out






Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
I had a really good experience with Guaranteed Motor
I had a really good experience with Guaranteed Motor Cars. The whole process was smooth, no pressure, and they were upfront about everything. The staff was helpful and made sure I left confident in my purchase. Definitely 100% recommend them if you’re looking for a solid car buying experience.






Used
2021 Mercedes-Benz E-Class E 350 4MATIC
Vehicle information
Features
Reviews
Car purchase .
Car purchase . We had a great experience in purchasing Versa. Hi Laura recommend this dealership. In the past, I was using Service at this dealership.
There are 20 matching cars close to your year range.






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2022 Mercedes-Benz E-Class 4MATIC
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Mercedes-Benz Certified
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2019 Mercedes-Benz E-Class 4MATIC
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Mercedes-Benz Certified
2023 Mercedes-Benz E-Class E 450 4MATIC
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Mercedes-Benz Certified
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2022 Mercedes-Benz E-Class 4MATIC
Vehicle information
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Used
2020 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
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Used
2020 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
Features






Used
2019 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features






Used
2023 Mercedes-Benz E-Class 4MATIC
Vehicle information
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Used
2019 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features






Used
2022 Mercedes-Benz E-Class 4MATIC
Vehicle information
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Used
2019 Mercedes-Benz E-Class 4MATIC
Vehicle information
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Mercedes-Benz Certified
2023 Mercedes-Benz E-Class E 450 4MATIC All-Terrain
Vehicle information
Features






Mercedes-Benz Certified
2022 Mercedes-Benz E-Class 4MATIC
Vehicle information
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Used
2020 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
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Mercedes-Benz E-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2026 Mercedes-Benz E-Class | $71,615 | |
2025 Mercedes-Benz E-Class | $61,777 | 9 Good deals |
2020 Mercedes-Benz E-Class | $21,995 | 5 Good deals |
2018 Mercedes-Benz E-Class | $19,849 | 3 Good deals |
2017 Mercedes-Benz E-Class | $14,995 | 5 Good deals |
2016 Mercedes-Benz E-Class | $11,991 | 3 Good deals |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)

How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $36,405, with pricing starting at $21,326.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
Style | |
---|---|
E 350 RWD Sedan | E 350 4MATIC Sedan |
Inventory price | |
Starting at $54,250 | Starting at $56,750 |
Combined MPG | |
25 | 25 |
Engine | |
255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
Style | |||||
---|---|---|---|---|---|
E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
Inventory price | |||||
Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
Combined MPG | |||||
25 | 24 | 25 | 26 | 26 | 25 |
Engine | |||||
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz E-Class
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.