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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class
for sale
near
Forest Park, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
I have purchased new Mercedes and I had fantastic
I have purchased new Mercedes and I had fantastic experience at Mercedes-Benz of Westmont.Very kind and friendly people.Especially thank you to my sales agent Mr.Earl Sklar.Nicest person I have ever had to work with.He was very professional,respectful and knowledge.Made purchasing process very smooth and comfortable.I highly recommending Mr.Earl and his team to anyone!
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰
Used
2021 Mercedes-Benz E-Class E 450 4MATIC
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Reviews
I have owned Mercedes for 30 years.
I have owned Mercedes for 30 years.This has been the best dealership of all.Totally perfect
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.
Used
2021 Mercedes-Benz E-Class E 350 4MATIC
Vehicle information
Features
Reviews
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.
Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
Features
Reviews
Excellent Sherry was so helpful and did an amazing
Sherry was amazing & did an excellent job at finding us the suv we wanted. We would definitely buy from her again and she became a great friend! The entire experience was seamless. We couldn’t be happier.
This car is why you buy a Mercedes-Benz.
I'm replacing a 17 y/o E-320 that I loved. I am now infatuated with the New 2021 E-450 4 matic it just so happens to be the Motor Trend car of the year. Very nice exterior styling. Fantastic interior. all the latest technology and a great interior. The strait V-6 with turbo is smooth as silk. The optional Air Body control suspension makes for a fantastic smooth ride.
Used
2021 Mercedes-Benz E-Class 4MATIC
Vehicle information
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Reviews
Brian York continues to be the reason I keep buying cars
Brian York continues to be the reason I keep buying cars from Genesis of North Aurora. He is kind, knowledgeable, and always has my best interests at heart. This is the 4th car/suv I’ve purchased from Brian in the past 18mo. His customer service is exceptional. I will continue to recommend my friends and family to Brian York at Genesis of North Aurora.
Love my Car
The vehicle meets all of my needs. I special ordered the vehicle with the color and leather interior I prefer. It arrived exactly the way I wanted.
Used
2021 Mercedes-Benz E-Class 4MATIC
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Reviews
They were very accommodating it took awhile for the
They were very accommodating it took awhile for the financing so we was there pretty late so customer service was great. Thanks Adrian his first day and sale!
Used
2021 Mercedes-Benz E-Class 4MATIC
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Battery
Todd was very helpful and made sure my car was pulled inside when leaving as it was very slippery outside
Used
2021 Mercedes-Benz E-Class 4MATIC
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Reviews
Great follow up, I haven't at this point found unit I was
Great follow up, I haven't at this point found unit I was pleased enough to purchase. Thanks for your attention...........done
Mercedes-Benz Certified
2021 Mercedes-Benz E-Class
Vehicle information
Used
2021 Mercedes-Benz E-Class E 350 4MATIC
Vehicle information
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Reviews
We recently purchased a 2025 C300 4Matic from Romeoville
We recently purchased a 2025 C300 4Matic from Romeoville MB, and the experience was outstanding from start to finish. Jayda and the entire staff were incredibly courteous, knowledgeable, and helpful throughout the process. They made everything smooth and stress-free. Highly recommend Romeoville MB for anyone looking for a Mercedes-Benz vehicle and top-tier customer service!
There are 20 matching cars close to your year range.
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Mercedes-Benz E-Class prices by year
| Model year | Average price | Deals |
|---|---|---|
| 2026 Mercedes-Benz E-Class | $78,343 | 2 Good deals |
| 2025 Mercedes-Benz E-Class | $67,120 | 9 Good deals |
| 2024 Mercedes-Benz E-Class | $58,167 | |
| 2019 Mercedes-Benz E-Class | $31,683 | 1 Good deal |
| 2018 Mercedes-Benz E-Class | $22,656 | 3 Good deals |
| 2014 Mercedes-Benz E-Class | $14,427 | 2 Good deals |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)
How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $34,508, with pricing starting at $19,995.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
| Style | |
|---|---|
| E 350 RWD Sedan | E 350 4MATIC Sedan |
| Inventory price | |
| Starting at $54,250 | Starting at $56,750 |
| Combined MPG | |
| 25 | 25 |
| Engine | |
| 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
| Style | |||||
|---|---|---|---|---|---|
| E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
| Inventory price | |||||
| Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
| Combined MPG | |||||
| 25 | 24 | 25 | 26 | 26 | 25 |
| Engine | |||||
| 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz E-Class
Compare the 2021 Mercedes-Benz E-Class
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
