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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class
for sale
near
Lantana, FL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
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Reviews
Astounding experience buying my new 2026 Mercedes at
Astounding experience buying my new 2026 Mercedes at Delray Beach , Florida. Beautiful showroom. Excellent service . An all around great experience buying a new car. Everything was done at the showroom, insurance change, plate change etc.
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰
Used
2021 Mercedes-Benz E-Class E 350
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Reviews
Mercedes Benz at coconut Creek offers very good service
Mercedes Benz at coconut Creek offers very good service from the dealer's agent. He was well accommodating and understands my need. He never leave me and offer for me to test all the models until I was satisfied.
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.
Used
2021 Mercedes-Benz E-Class E 450
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Dwarn Troutman has great patience and knowledge.
Dwarn Troutman has great patience and knowledge. I didn’t know I was buying but his professionalism convinced me to purchase
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.
Used
2021 Mercedes-Benz E-Class E 350
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Reviews
Bobbie was the best!
Bobbie was the best! Very easy and professional. She is an asset to Mullinax. Dan Thomas
This car is why you buy a Mercedes-Benz.
I'm replacing a 17 y/o E-320 that I loved. I am now infatuated with the New 2021 E-450 4 matic it just so happens to be the Motor Trend car of the year. Very nice exterior styling. Fantastic interior. all the latest technology and a great interior. The strait V-6 with turbo is smooth as silk. The optional Air Body control suspension makes for a fantastic smooth ride.
Used
2021 Mercedes-Benz E-Class E 350 4MATIC
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Reviews
Used Car
Scott Crowder took time to go over my needs as I was researching a used car. When I make my final decision he will be my go to.
Love my Car
The vehicle meets all of my needs. I special ordered the vehicle with the color and leather interior I prefer. It arrived exactly the way I wanted.
Used
2021 Mercedes-Benz E-Class
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My Carmax Experience
On December 23rd of 2016 I purchased a 2014 Jeep Patriot from the Pompano Beach Carmax (Sample Road). My wife is pregnant and will soon give birth to our first child. Before this we were a one car family with a Fiat 500 and my wife was very concerned about not having a car to bring baby boy home from the hospital in, not to mention to make it to all of the Doctor appointments for wellness checks in. So, I decided why not make the purchase a Christmas present/surprise since we needed one anyways! Only problem was I had this revelation on Wednesday December 21, 2016 and Carmax was to be closed on the 24th and 25th for Christmas. The real issue was that the perfect car (She had been wanting a white Patriot for a few years now) was all the way in Clearwater, FL... some 250 miles away. I was told by the sales rep at Pompano Beach that while it was possible the car may be there by Friday, in time for me to pick up prior to Christmas, it was in no way a certainty. I then contacted the Clearwater store to speak with someone who handles the outgoing shipments and he basically told me that it was not going to happen. From my understanding, the way it works with Carmax is when the car you want is at a location less than 200 miles Carmax will do the shipping itself and it usually takes 1-3 days. But when it is further than that they outsource to carrier companies. In that case they have to wait until they have enough cars to send to make it economical for them to do so and also deal with bidding/price hunting etc... which complicates the who thing and makes everything take much longer. After learning all of this I gave the corporate office a call and got in touch with a Emilee, an analyst from the Carmax Customer Care Team. I explained my situation and how much it would mean to my wife and I (both in the form of glee for her and reduced anxiety for the both of us) if they could somehow get the car to Pompano Beach in time for me to pick up on Friday. Before the end of the week Emilee had gotten a whole team of people in the corporate office working on getting the car to us in time. I received telephone updates from her all along the way. By Thursday afternoon I received an email informing me that the car was in transit, followed by a call from Emilee letting me know that everything worked out and the car should be there Thursday evening or Friday morning and a call from the Sales Manager at the Pompano Beach store letting me know that he had spoken to Emilee and once the car arrived they were going to expedite the "unpacking" and everything that that entails. The real cherry on top came on January 3rd when my wife received a FedEx package while I was at work. Inside she found a set of very nice swaddling blankets and a card that read: "Chris, Thank you so much for letting our Pompano Beach Team help you find your new-to-you Jeep Patriot for your growing family! Here's a small token from CarMax to welcome your new addition. We hope your Jeep Patriot takes you on incredible new adventures! Sincerely, Emilee, Your CarMax Customer Care Team" Everyone was super amazing and I could not be more grateful for the professional and caring people at both the local Sample Road Pompano Beach Store and the Corporate office. Thanks to Cristy (Pompano Beach sales rep) as well for making the whole process and painless as possible. As a side note: The Patriot was absolutely immaculate inside and out despite having 27k miles on it, my wife would have sworn it was new before she saw the odemeter... She was happy I saved us some money ;)
Used
2021 Mercedes-Benz E-Class E 350
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Reviews
From the moment I stepped onto the lot at Florida Fine
From the moment I stepped onto the lot at Florida Fine Cars, I knew I was in the right place. In an era where genuine customer service feels rare, this team reminded me what true professionalism and hospitality look like. Every interaction—whether with the front staff, the sales team, or management—was warm, patient, and sincerely focused on making my experience exceptional. But I have to give a special thank you to Ralph, who is truly one of a kind. His knowledge, honesty, and ability to connect with customers is unmatched. Ralph doesn’t just sell cars—he builds trust. He made the entire process smooth, transparent, and enjoyable, and he treated me and my family with a level of respect and friendliness that left a lasting impression. People like him are the reason this dealership stands out in Florida. The prices were unbeatable, the inventory was impressive, and the service was nothing short of extraordinary. Florida Fine Cars has earned my loyalty—my family and I will be buying our vehicles from them from now on. If you’re looking for a dealership that actually cares about you, listens to you, and goes above and beyond to earn your business, look no further. Florida Fine Cars knows what true customer service is. Thank you again to Ralph and his entire team for delivering a world-class experience. Highly recommended!
Used
2021 Mercedes-Benz E-Class E 450 4MATIC
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BRAMAN GREAT - BENTLEY USA DISAPPOINTMENT
DRIVEN BENTLEYS 15 YEARS. 2015 GT 14,000 MI. WATER PUMP LEAKED AND FOUND DEFECTIVE. (SHOULD LAST 70-100,000 MI) PEGGY OBTAINED PAYMENT FOR THE DEFECTIVE PART FROM BENTLEY BUT NOT FOR THE INSTALLATION. I HAD TO PAY $2000. WROTE TO BENTLEY CEO WITH NO RESULT. I BELIEVE THAT A "QUALITY LUXURY" COMPANY SHOULD BE RESPONSIBLE FOR ANY DEFECTIVE PARTS THEY INSTALL. THE MANUFACTURER OF THE DEFECTIVE PART AS WELL. i WILL CONTINUE TO FIGHT FOR THIS PRINCIPLE.
Used
2021 Mercedes-Benz E-Class E 350
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Had a great experience buying my Mercedes C-Class at
Had a great experience buying my Mercedes C-Class at Mercedes-Benz of Coconut Creek. The process was smooth, the team was professional, and everything went very efficiently. Very happy with my purchase!
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Mercedes-Benz E-Class prices by year
| Model year | Average price | Deals |
|---|---|---|
| 2026 Mercedes-Benz E-Class | $72,979 | |
| 2025 Mercedes-Benz E-Class | $71,880 |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)
How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $34,501, with pricing starting at $19,995.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
| Style | |
|---|---|
| E 350 RWD Sedan | E 350 4MATIC Sedan |
| Inventory price | |
| Starting at $54,250 | Starting at $56,750 |
| Combined MPG | |
| 25 | 25 |
| Engine | |
| 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
| Style | |||||
|---|---|---|---|---|---|
| E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
| Inventory price | |||||
| Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
| Combined MPG | |||||
| 25 | 24 | 25 | 26 | 26 | 25 |
| Engine | |||||
| 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz E-Class
Compare the 2021 Mercedes-Benz E-Class
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
