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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz S-Class
for sale
near
Chevy Chase Section Five, MD
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC






Used
2021 Mercedes-Benz S-Class S 580 4MATIC






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Quality Service
Went in for a repair and was very satisfied with the turnaround time to get the service done and return my car back to me.
Luxury
Luxury at its best, you can’t get better than that with this price range. S 580 is the way to go, the 8 cylinders are so smooth yet so sporty. This car can be Rolls Royce luxury and lamborghini urus if it wants






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Always great service!
I have been going to American Service Center for over 20 years for my Mercedes service needs. They are always courteous, efficient, and honest. If there is ever an issue it is handled promptly.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Everyone was very helpfull.
Everyone was very helpfull. Management and service went above and beyond, and the price the was appropriate!
Love my Mercedes
I have been driving Mercedes Benz s class vehicles for over 10 years, traded every 3-4 years and have been very happy, always have them serviced at the dealer, always received a loaner, no complaints.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I had a great buying experience.
I had a great buying experience. My salesman, Paul was wonderful and the finance department was great as well. Definitely recommend Mercedes of Arlington






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Buying my first car felt a little intimidating at first,
Buying my first car felt a little intimidating at first, but Kingstowne Motorcars made it surprisingly easy. Ali walked me through every step, explained everything clearly, and made sure I felt comfortable the whole time. I really appreciated how patient and honest they were—it made the whole experience feel right.
An Absolute Dream
I have owned 6 S Class (SonderKlas) cars in my life and each and every single one has been problem free and a pure joy to own, drive, and admire. The 2021 S580 however.. Well this car is truly something special and not an incremental upgrade! This thing is crazy





Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I had an awesome experience dealing with Mercedes Benz of
I had an awesome experience dealing with Mercedes Benz of Tysons Corner. This was the best car purchase experience I have had. The sales person Trivian Anand is such a great customer advocate. The manager, Pascuale, bent over backwards to accomodate me. The finance manager (Sue Kim) was very transparent. Overall it was pure joy to deal with these guys contrary to most other car buying experiences






Used
2021 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
Reviews
Best Car Dealership Experience
On September 28, 2023 I had the pleasure of visiting Universal Auto Group Dealership in Silver Springs Maryland. I could not believe the the selections of beautiful used cars. I know exactly what i wanted and in less than one hour I was finished and driving away in my 2020 750I BMW! What an awesome experience it was!! Looking forward to shopping with Universal Auto Group in the future!






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Awesome deal.
Excellent service from the first contact, they are the best, I will definitely buy from them again, It is simply a great purchasing experience 100% Satisfied.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Excellent dealership!
Excellent dealership! The price you see on their advert page is the price you pay. That's so rare now since covid. Excellent salesman and Excellent finance department.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Yulila was super friendly and helpful.
Yulila was super friendly and helpful. She didn’t pressure us and gave us great info. Super happy with our purchase
There is 1 matching car close to your year range.






Used
2019 Mercedes-Benz S-Class 4MATIC
Vehicle information
Features
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Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $115,900 | |
2023 Mercedes-Benz S-Class | $69,995 | 8 Good deals |
2022 Mercedes-Benz S-Class | $54,995 | 8 Great deals |
2015 Mercedes-Benz S-Class | $16,950 | 7 Good deals |
2014 Mercedes-Benz S-Class | $15,995 | 2 Good deals |
About the 2021 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2021 Mercedes-Benz S-Class cost?
The 2021 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 S-Class is $75,246, with pricing starting at $50,995.
What is the MPG of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class offers up to 20 MPG in city driving and 29 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz S-Class reliable?
The 2021 Mercedes-Benz S-Class has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 S-Class owners.
Is the 2021 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
100% of drivers recommend this car
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $109,800 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 560 (2 styles)
Style | |
---|---|
S 560 Cabriolet | S 560 4MATIC Coupe |
Inventory price | |
Starting at $140,000 | Starting at $131,400 |
Combined MPG | |
20 | 20 |
Engine | |
463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) | 463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $116,300 |
Combined MPG |
20 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz S-Class
Compare the 2021 Mercedes-Benz S-Class
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