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Used
2021 Mercedes-Benz S-Class
for sale
near
Chevy Chase Section Five, MD
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
Franklin is great.
Franklin is great. Thank you for your support help and patience with me. Love the car. At rides great. The paperwork and process was fast
Used
2021 Mercedes-Benz S-Class S 580
Vehicle information
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Reviews
Matthew Forbes
Matt is really helpful and friendly. Even though we didn’t make the purchase since I was looking for to get a better trade in price, but overall it’s very good! I have been to carmax twice and both of them are all very good facilities and very professional working process, definitely recommend Carmax!
Love my Mercedes
I have been driving Mercedes Benz s class vehicles for over 10 years, traded every 3-4 years and have been very happy, always have them serviced at the dealer, always received a loaner, no complaints.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Reviews
I recently purchased a Porsche Panamera Turbo S E-Hybrid
I recently purchased a Porsche Panamera Turbo S E-Hybrid from Universal Auto Group, and I couldn’t be more pleased with the experience. From start to finish, the process was smooth, professional, and stress-free. Baker in Sales and Jessica in Finance went above and beyond to make my sight-unseen purchase easy and comfortable. They answered all of my questions, handled the details with care, and even coordinated the transport of my new car to Florida. When the car arrived, it was exactly as described — no surprises, no issues, just the dream car I had hoped for. After a month of ownership, I can confidently say I made the right choice trusting Universal Auto Group with such an important purchase. If you’re considering buying from them, especially from a distance, I highly recommend it. Their professionalism, attention to detail, and commitment to customer service truly stand out.
An Absolute Dream
I have owned 6 S Class (SonderKlas) cars in my life and each and every single one has been problem free and a pure joy to own, drive, and admire. The 2021 S580 however.. Well this car is truly something special and not an incremental upgrade! This thing is crazy
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Reviews
I post a review on June 7 2025 and today July 26, 2025 we
I post a review on June 7 2025 and today July 26, 2025 we had meeting with the manager James and he settled the price issue we had with the purchase of Honda civic 2016. Thank you James
Luxury
Luxury at its best, you can’t get better than that with this price range. S 580 is the way to go, the 8 cylinders are so smooth yet so sporty. This car can be Rolls Royce luxury and lamborghini urus if it wants
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I read the reviews, considered all the good and the bad
I read the reviews, considered all the good and the bad and still took a chance. Found a local person familiar with the type of car for a PPI. They di fix the AC on their dime. The car did have a minor accident on the drivers passenger door, not reported on the Experian report. This was not a deal breaker for me. I chose to fly out of state to make sure I got the title in my hand. Everyone was pleasant to work with from the moment I contacted them. I took one star off only because I arrived around 10:30am and wasn't able to leave till 4pm. I drove the car 500+ miles home without any problems.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
The overall process felt organized and honest, which is
The overall process felt organized and honest, which is rare when buying a car. I left feeling like I got a fair deal and a stress-free experience.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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We can’t thank Kelly Vafadar and DARCARS Volvo enough for
We can’t thank Kelly Vafadar and DARCARS Volvo enough for the support and care extended to us in purchasing our new XC90. The quick response to questions and making the process smooth in closing the deal is why we will always recommend the dealership.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
Thank you for helping me with the safety recall and
Thank you for helping me with the safety recall and making the process a positive experience
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
Great online experience but I receive too many duplicate
Great online experience but I receive too many duplicate emails. Online rep, sales rep and another sales rep. Multiple emails, BUT I prefer that over little email.
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Reviews
Kurt was attentive, responsive and informative.
Kurt was attentive, responsive and informative. I drove to the dealership from central PA on Saturday, test drove it and purchased my Lexus LS500 F Sport on the spot. Minimal paperwork. Thank you Kurt!
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Mercedes-Benz S-Class prices by year
| Model year | Average price | Deals |
|---|---|---|
| 2026 Mercedes-Benz S-Class | $146,579 | |
| 2023 Mercedes-Benz S-Class | $71,036 | 4 Good deals |
| 2022 Mercedes-Benz S-Class | $65,714 | 5 Great deals |
| 2019 Mercedes-Benz S-Class | $35,103 | 3 Good deals |
| 2018 Mercedes-Benz S-Class | $31,882 | 9 Great deals |
| 2017 Mercedes-Benz S-Class | $28,485 | 5 Great deals |
| 2016 Mercedes-Benz S-Class | $24,553 | 5 Great deals |
| 2015 Mercedes-Benz S-Class | $25,672 | 11 Good deals |
About the 2021 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)
How much does the 2021 Mercedes-Benz S-Class cost?
The 2021 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 S-Class is $59,710, with pricing starting at $45,995.
What is the MPG of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class offers up to 20 MPG in city driving and 29 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz S-Class reliable?
The 2021 Mercedes-Benz S-Class has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 S-Class owners.
Is the 2021 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.8
- Exterior 5.0
- Reliability 5.0
100% of drivers recommend this car
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.8
- Exterior 5.0
- Reliability 5.0
S 500 (1 style)
| Style |
|---|
| S 500 4MATIC Sedan |
| Inventory price |
| Starting at $109,800 |
| Combined MPG |
| 24 |
| Engine |
| 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 560 (2 styles)
| Style | |
|---|---|
| S 560 Cabriolet | S 560 4MATIC Coupe |
| Inventory price | |
| Starting at $140,000 | Starting at $131,400 |
| Combined MPG | |
| 20 | 20 |
| Engine | |
| 463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) | 463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) |
S 580 (1 style)
| Style |
|---|
| S 580 4MATIC Sedan |
| Inventory price |
| Starting at $116,300 |
| Combined MPG |
| 20 |
| Engine |
| 496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz S-Class
Compare the 2021 Mercedes-Benz S-Class
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
