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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 GMC Sierra 2500 trucks
for sale
near
Pierron, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Great service!
Great service!I was picked up at the airport in a very timely manner.I recommend this dealership to anyone I meet that is looking for a vehicle.
Beautiful truck
I love my 2021 GMC Denali 2500HD. I have gotten more complements on this truck than any other vehicle that I have owned. I get great highway fuel milage average 19-26mpg,which is great for a heavy duty truck!






GMC Certified
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
It was a great experience, I purchased the 2020 GMC
It was a great experience, I purchased the 2020 GMC Canyon Denali from Laura Buick GMC, I love the vehicle and service rendered by the dealership was incredible. They are a great dealership to patronize because they make their customers feel valued.
Best truck I ever owned
Love my GMC. Owned a Chevy and this absolutely beats it hands down. Never had any issues. Inside is very comfortable and can't imagine driving anything else






Used
2021 GMC Sierra 2500 SLT
Vehicle information
Features
Reviews
Justin Scheaffer supported my acquisition of a 2025 GMC
Justin Scheaffer supported my acquisition of a 2025 GMC Denali truck with total customer care in mind. From finding the exact vehicle I wanted to it delivery, Justin was there, front and center - An Outstanding job; definitely a go-to professional who gets my highest rating!! Thanks Justin - Will stay in touch!
GMC 2500 HD AT4
This is the first diesel I have owned. The power is amazing and I really like the room inside the cab. This truck is a beast... Love it!






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
I always get great customer service from everyone at
I always get great customer service from everyone at Laura Buick. My go to guy is David Day. They always do a great job with any issues with my car.
Never had one. Always wanted one and love it.
I love my Denali. Beautiful truck inside out. When I drive down the road all heads turn. I couldn't have made a better choice. That's Cortez for you good service.






Used
2021 GMC Sierra 2500 SLT
Vehicle information
Features
Reviews
Great experience.
Great experience. Jimmy was great and answered all my questions. love my new Yukon XL 2025. I would definitely recommend Jimmy and this dealership to my friends and family.
Early to tell truck has less than 100 miles
Truck was bought specifically to our travel trailer. We have to wait for 1000 break in before we can tow the trailer. So far the truck is very quiet, smooth running, & comfortable to drive. We were pleasantly surprised at how much interior storage space is available. Having the bed steps before rear tires and in the bumper sides is very nice. Bed rails are even with my shoulders so the steps get used a lot.






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GMC Sierra 2500 prices by year
Model year | Prices from | Deals |
---|---|---|
2026 GMC Sierra 2500 | $60,958 | |
2025 GMC Sierra 2500 | $53,095 | 2 Good deals |
About the 2021 GMC Sierra 2500
Base shown (base trim).
- Seating
- 3
- Door count
- 2
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 0
- Transmission
- 6-Speed A/T
- Engine
- 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel)

How much does the 2021 GMC Sierra 2500 cost?
The 2021 GMC Sierra 2500 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 Sierra 2500 is $53,193, with pricing starting at $27,900.
What are some similar vehicles and competitors of the 2021 GMC Sierra 2500?
The 2021 GMC Sierra 2500 compares to and/or competes against the following vehicles:
Is the 2021 GMC Sierra 2500 reliable?
The 2021 GMC Sierra 2500 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 Sierra 2500 owners.
Is the 2021 GMC Sierra 2500 a good truck?
Below are the Cars.com consumer ratings for the 2021 GMC Sierra 2500.
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
75% of drivers recommend this car
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
AT4 (2 styles)
Style | |
---|---|
4WD Crew Cab 172" AT4 | 4WD Crew Cab 159" AT4 |
Inventory price | |
Starting at $59,300 | Starting at $59,100 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Base (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
4WD Crew Cab 159" | 2WD Crew Cab 172" | 4WD Crew Cab 172" | 2WD Crew Cab 159" | 2WD Double Cab 162" | 4WD Double Cab 162" | 4WD Double Cab 149" | 2WD Double Cab 149" | 2WD Reg Cab 142" | 4WD Reg Cab 142" |
Inventory price | |||||||||
Starting at $43,400 | Starting at $40,800 | Starting at $43,600 | Starting at $40,600 | Starting at $39,000 | Starting at $41,800 | Starting at $41,600 | Starting at $38,800 | Starting at $36,200 | Starting at $39,000 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Denali (2 styles)
Style | |
---|---|
4WD Crew Cab 172" Denali | 4WD Crew Cab 159" Denali |
Inventory price | |
Starting at $65,700 | Starting at $65,500 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLE (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
2WD Crew Cab 172" SLE | 4WD Crew Cab 159" SLE | 2WD Crew Cab 159" SLE | 4WD Crew Cab 172" SLE | 2WD Double Cab 162" SLE | 2WD Double Cab 149" SLE | 4WD Double Cab 149" SLE | 4WD Double Cab 162" SLE | 4WD Reg Cab 142" SLE | 2WD Reg Cab 142" SLE |
Inventory price | |||||||||
Starting at $45,600 | Starting at $48,200 | Starting at $45,400 | Starting at $48,400 | Starting at $43,800 | Starting at $43,600 | Starting at $46,400 | Starting at $46,600 | Starting at $44,400 | Starting at $41,600 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLT (8 styles)
Style | |||||||
---|---|---|---|---|---|---|---|
4WD Double Cab 162" SLT | 2WD Double Cab 149" SLT | 2WD Double Cab 162" SLT | 4WD Double Cab 149" SLT | 4WD Crew Cab 159" SLT | 2WD Crew Cab 159" SLT | 2WD Crew Cab 172" SLT | 4WD Crew Cab 172" SLT |
Inventory price | |||||||
Starting at $54,600 | Starting at $51,600 | Starting at $51,800 | Starting at $54,400 | Starting at $56,200 | Starting at $53,400 | Starting at $53,600 | Starting at $56,400 |
Combined MPG | |||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 GMC Sierra 2500
Compare the 2021 GMC Sierra 2500
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.