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Used
2022 Lexus RX 350
for sale
near
Claycomo, MO
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
30k service, plus some shimmy in the front brakes.
30k service, plus some shimmy in the front brakes. Jen, our advisor, was right up front with estimates; keeping us informed, and getting our loaner. Even tho' we had to spend $$$s, it was a non-stressful experience.
Love this car.
Love this car. Sitting in the driver’s seat is so comfortable. Silky smooth engine. Rides so nice and quiet. We have looked for this color Grecian water for a long time. Wanted no newer than a 2022 because we didn’t want the 4 cylinder. The 3.5 V6 runs so smooth. Would definitely recommend the purchase of this SUV.






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
True professionals, beyond expectations, caring!
Kyle and his staff are true professionals. They went beyond expectations in how we were cared for in buying our car. Without hesitation, Kyle has also helped us with questions about other cars in my family, unrelated to those he was selling. His service orientation is exceptional! Ive also had great conversations with him about life, just sitting at his desk. 5 star recommendation!!
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Great experience from the time time we walked in the door
Great experience from the time time we walked in the door all the way through the car purchase. Our salesperson, Jeff B, was fantastic to work with. I hate buying cars but this was painless. I highly recommend Jeff and the Hendrick team.
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
I use a neighborhood mechanic shop for general
I use a neighborhood mechanic shop for general maintenance car care. But this time, I needed a front parking sensor diagnosed and consequently replaced and reprogrammed. I was told I needed to take the car to a dealer. My previous experiences with Hendricks Lexus was a good one and my issue was resolved quickly and painlessly. I was delighted that this time I happened to get the same service consultant that had handled my last issue. Willie Steineger helped me again with graciousness and efficiency. I was in and out quickly, given a beautiful loaner and picked up my own car the next morning, freshly washed and back to flawless operational condition again. Each time I have taken my car to Hendricks Lexus, I have been treated with respect and kindness, and the team behind the scenes does their thing with thoroughness and without fanfare.
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Always a pleasure doing business with Hendrick.
Always a pleasure doing business with Hendrick. First class all the way in every department. Very friendly employees and clean environment. The lounge area is equally comfortable and nice and they clearly want your time in the lounge to be enjoyable.
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Above and Beyond
Our company truck was due for maintenance and I was holding off due to the Shelter in Place order. In the meantime, the brakes started to grab a little, so I called Chase at Bob Allen Ford. I was relived to hear they had a plan for avoiding contact, and sent a loaner and took our truck in. A day later all is up to par mechanically and the truck is retuned. Bravo to Brad and his team at Bob Allen Ford on Metcalf. Tracy Allen No Relation






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Hendrick Lexus is a fantastic place to buy a car, new or
Hendrick Lexus is a fantastic place to buy a car, new or used. If you are looking for a new vehicle, see Nate Perex, he is fantastic to work with.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
One of the best car buying experiences i’ve had!
One of the best car buying experiences i’ve had! Rich was very professional, witty, knowledgeable, and made buying a car about as enjoyable as it could possibly be. The whole crew was very helpful, made the process incredibly easy from start to finish and most importantly were NOT pushy. We will buy from them again!






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
I took my Lexus ES350 in for service.
I took my Lexus ES350 in for service. Check in was fast, my loaner was ready and my car was ready for pick up when promised. We have purchased 5 Lexus autos from Hendrix North. They are professionals!
There are 20 matching cars close to your year range.






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2020 Lexus RX 350 Base
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Certified
2024 Lexus RX 350 Premium Plus
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Certified
2023 Lexus RX 350 Premium
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Certified
2023 Lexus RX 350 Premium
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Certified
2023 Lexus RX 350 Luxury
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Certified
2024 Lexus RX 350 Premium
Vehicle information
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Certified
2023 Lexus RX 350 Premium
Vehicle information
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Certified
2023 Lexus RX 350 Premium
Vehicle information
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Used
2023 Lexus RX 350 Premium
Vehicle information
Features






Used
2020 Lexus RX 350 Premium
Vehicle information
Features






Certified
2024 Lexus RX 350 Premium
Vehicle information
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Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $53,206 | |
2023 Lexus RX 350 | $47,782 | 5 Good deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,313, with pricing starting at $27,000.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Lexus RX 350
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