Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Lexus RX 350
for sale
near
Hoffman Estates, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 Base






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Amazing experience buying IX from Bill Jacobs.
Amazing experience buying IX from Bill Jacobs. Michael Fontana was fantastic in hand holding me along the way - all while making a virtual purchase! BMW issued a temporary recall block on this and many other similar vehicles and the purchase was held for more than a week. Among other things, Michael would update me the status on a daily basis and promptly facilitated the purchase right after the recall fix. I received the car yesterday and it looks more fabulous than I what I expected! Thanks again to Michael, April and the rest of folks at Bill Jacobs.
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Fields Lexus Glenview,The best car buying
Fields Lexus Glenview,The best car buying experienced,very professional people to deal with.Highly recommended.
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Repeat customer for service
pretty good service. always courteous and consistent.
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.




Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Trent greeted me as soon as I stepped out of my car.
Trent greeted me as soon as I stepped out of my car. He told me that I was going to receive VIP treatment and he did not disappoint me. He did a presentation of both MDX that I wanted to see by having all doors open and a brief walk through and overview of the features before the test drive. He was knowledgeable, courteous, respectful and absolutely the best car sales experience I’ve ever had in my entire life.






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
Sal was our salesman and I was so happy with him.
Sal was our salesman and I was so happy with him. He was patient and answered all my many questions. We were treated so well throughout the whole process, including the loan application. No stress and the car was prepped so that it looked new. Very happy.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Staff there were nice and made the dealership experience
Staff there were nice and made the dealership experience less painful. Worked with Juan and Ryan on the purchase of a used MDX. They were able to work out a deal to accommodate our agreement.






Used
2022 Lexus RX 350 Base
Vehicle information
Features






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
NICK V
THANK YOU SO MUCH NICK V FOR ALL THE HELP TO GET US IN A PREOWNED COROLLA! Nick was smooth going and easy to work you!






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Bought a 2025 Lexus TX from Dylan, easy process and quick
Bought a 2025 Lexus TX from Dylan, easy process and quick service for add-ons. I don’t even live in the area, but saw what I wanted on the internet. Drove it home next day.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Dylan was fantastic in helping me purchase my new
Dylan was fantastic in helping me purchase my new vehicle. It was a very positive experience.






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Jamie Brown was a great salesman and very helpful.
Jamie Brown was a great salesman and very helpful. Everything was exactly as promised. Time there to purchase was streamlined and efficient. Everyone was nice and helpful.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
I did the entire transaction online, which can always be
I did the entire transaction online, which can always be a bit stressful as the dealership is 10 hours away from me. Mike was my sales rep and I cannot imagine anyone being more responsive, thorough, and upfront about every part of the transaction. Professional, polite and personable, I always felt like I was in good hands. He picked me up at the airport, drove me back to the dealership, and I was on my way within an hour. I have purchased Mercedes, Audi, and other luxury brands, but this was by far the best customer service experience I have ever had purchasing a car. By the way, the vehicle, a Lexus LC 500 convertible is incredible as well!






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
Jose Garcia, the service man was very helpful.
Jose Garcia, the service man was very helpful.I?m assuming the quality of the repair is good. I also appreciated how fast they were able to finish the repair






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Mike was a pleasure to work with in the purchase of our
Mike was a pleasure to work with in the purchase of our new MDX. He answered all our questions and pointed out features and benefits of the car






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
I had the best car buying experience I have ever had!
I had the best car buying experience I have ever had! I cannot say enough good things about everyone that helped me. Everything went so smooth, from the paperwork, to the explanation of everything, to the time it took to get everything handled. Honestly, everything went perfectly. Every single person I interacted with at Lexus Naperville was so kind and helpful. They also really know their stuff. I asked a million questions about the car I wanted and the packages I was interested in and they were able to answer all my questions with ease. Everything was explained to me very well. I'm really glad I got them. I have with all my cars and trust me, they make the difference. Very worth it. I want to thank Kamil, Gabby, Ben and AP. If there is anyone I forgot I'm so sorry! I'm so grateful to each of them! Truly truly made the experience easy, completely stress free and I really did feel like I was in good hands. Oh also, the car I got was a used car. You wouldn't know it though. It is very clean, has no odor, and is GORGEOUS. I.LOVE.THIS.CAR. It's so fun to drive and I feel safe in it. Thank you so much!!






Vehicle information
Features
Reviews
Mazda Purchase
Very easy process to purchase my new Mazda. Sales were excellent and very attentive to my questions. I felt no sales pressure at any time during the purchase. Tom is an excellent sales person and I would definitely return to this dealership.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Highly recommend.
Highly recommend. Greeted us with a big smile on his face. Thank you Daniel Rico for the Buick.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Had an awesome experience with my purchase here.
Had an awesome experience with my purchase here. Everyone from the sales staff, GSM, and finance was timely and listened to my needs and questions. The price was pretty competitive as well. I wouldn’t hesitate making another purchase here.






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
I had a great experience working with Toni the salesman,
I had a great experience working with Toni the salesman, he answered all of my questions. i bought a BMW x5 the other day, for a great price. there was a small ding that i notices afterwords (a very minor ding). He gave me bindis number (the service advisor) and they took care of it. Awesome dealership and I will be recommending to friends and family.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
First time and very hesitant to do business with a new
First time and very hesitant to do business with a new dealer. But very happy with the service and follow up. Specifically with our salesman Sam. He really-really went above and beyond, not your pushy salesman and that is huge for us. From 1st contact to end, he was very much involved making sure our purchase experience was great. Overall, the Team @Land Rover Hinsdale have done a Fantastic JOB! -Thank you!
-
Prev - 1
- 2
-
Next
Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $55,049 | 3 Good deals |
2024 Lexus RX 350 | $51,350 | 26 Good deals |
2023 Lexus RX 350 | $44,795 | 7 Good deals |
2021 Lexus RX 350 | $31,995 | 3 Good deals |
2017 Lexus RX 350 | $17,949 | 11 Good deals |
2016 Lexus RX 350 | $21,376 | 2 Good deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,749, with pricing starting at $23,888.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Similar Cars
-
Acura RDX for sale
29 listings starting at $26,490
-
Mercedes-Benz GLE 350 for sale
4 Great Deals out of 20 listings starting at $31,488
-
Toyota Highlander for sale
2 Great Deals out of 63 listings starting at $26,990
Research the 2022 Lexus RX 350
Compare the 2022 Lexus RX 350
2022 Lexus RX 350 by city
-
2022 Lexus RX 350 in South Barrington, IL
34 listings starting at $33,495
-
2022 Lexus RX 350 in Streamwood, IL
35 listings starting at $33,495
-
2022 Lexus RX 350 in Schaumburg, IL
35 listings starting at $33,495
-
2022 Lexus RX 350 in Inverness, IL
34 listings starting at $33,495
-
2022 Lexus RX 350 in Hanover Park, IL
35 listings starting at $33,495
-
2022 Lexus RX 350 in East Dundee, IL
30 listings starting at $33,495
-
2022 Lexus RX 350 in Barrington Hills, IL
30 listings starting at $33,495
-
2022 Lexus RX 350 in Barrington, IL
35 listings starting at $33,495
-
2022 Lexus RX 350 in Rolling Meadows, IL
35 listings starting at $33,495
-
2022 Lexus RX 350 in Palatine, IL
34 listings starting at $33,495
-
2022 Lexus RX 350 in Roselle, IL
36 listings starting at $33,495
-
2022 Lexus RX 350 in Bartlett, IL
35 listings starting at $33,495
Lexus RX 350 trims
-
Lexus RX 350 2022 Base
24 listings starting at $36,490
Used 2022 Lexus RX 350 by body style
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}