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Used
2022 Lexus RX 350
for sale
near
Irwindale, CA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 Premium
Vehicle information
Features
Reviews
I had a pleasant experience with the agent who assisted
I had a pleasant experience with the agent who assisted me. He was very thorough with explaining everything and I was able to make a decision that I was willing to do. I highly appreciate everything he said.
Love this car.
Love this car. Sitting in the driver’s seat is so comfortable. Silky smooth engine. Rides so nice and quiet. We have looked for this color Grecian water for a long time. Wanted no newer than a 2022 because we didn’t want the 4 cylinder. The 3.5 V6 runs so smooth. Would definitely recommend the purchase of this SUV.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Wonderful service and staff.
Wonderful service and staff. Angel was my point of contact. Explained everything clearly and was transparent. Helped out with all my questions and made the process smooth. Worked with Kevin in finance. Super cool dude who loves to keep it light and help his customers. Would definitely purchase another vehicle here again. Thank you!
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own






Vehicle information
Features
Reviews
I bought a cla here, and they helped me do a lot in terms
I bought a cla here, and they helped me do a lot in terms of loans. Thank them very much. I like this car very much. The condition of the car is very good. They also helped me with a comprehensive inspection and maintenance for free. I will come here again after changing the car!
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Excellent, that's exactly the reason I don't mind
Excellent, that's exactly the reason I don't mind traveling the hour+ along with the pleasure of working with the technicians All the employees are always willing to assist. Thank you Lexus of Cerritos !
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.






Vehicle information
Features
Reviews
Ramon helped me finding the car I wanted from Cerritos
Ramon helped me finding the car I wanted from Cerritos Lexus. He is a real professional.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Our experience was how buying a car should be, fun and
Our experience was how buying a car should be, fun and easy. Everyone at the dealership was friendly and helpful. Salesman Richard Hahn was pleasant to work with and never once pressured us. When it was time to complete the paperwork with the finance department, Hussam Kallas took his time and patiently explained everything. We definitely recommend this dealer!






Vehicle information
Features
Reviews
Good job dealer introducing very well.
Good job dealer introducing very well. But result is not confimed and we will discuss it tomorrow and made final decision Angd get a suitable profits






Used
2022 Lexus RX 350 Premium
Vehicle information
Features
Reviews
Jack was very helpful an quick with everything answered
Jack was very helpful an quick with everything answered all my questions great customer service.






Used
2022 Lexus RX 350 Premium
Vehicle information
Features
Reviews
Good communication with updated status/ check results/
Good communication with updated status/ check results/ process; the entire experience/ progress was effortless efficient.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Prem and Collin were the best.
Prem and Collin were the best. We told them what we wanted and they gave us that and more. Toyota/Auto Nation did us right. Recommend going to them for your car needs.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Best customer service I?
Best customer service I?ve ever gotten at a dealership from sales to finance to service everything was amazing!! K-lee, Ab and Hector were the ssoo nice and friendly I felt comfortable with them!






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
“Shoutout to Brayan he was super helpful and
“Shoutout to Brayan he was super helpful and knowledgeable 10/10 recommend made me felt welcomed!






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
I bought a used car.
I bought a used car. They fixed minor scratches and made it look like new. We got a great deal and excellent service. You should buy a car there!






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Richard Garcia is excelent at what he does.
Richard Garcia is excelent at what he does. He provides great customer service and very knowledble about the cars. Thank you for your great service.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Outstanding service.
Outstanding service. Kirk Putman worked above and beyond the level of expert. My Prius “Fix” was completed in less time than predicted. And all the job categories were finished perfectly. Kirk, you are the MAN!






Used
2022 Lexus RX 350 Premium
Vehicle information
Features
Reviews
Chris was great
Got a wonderful used Fiat from Chris. The experience was good and got in and out in under 3 hours. From stepping on the lot to driving away. Was the most stress free car buying experience I have ever had.
Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Roger Sanchez thank you for the help on my father in laws
Roger Sanchez thank you for the help on my father in laws purchase he was very excited and thankful for your patience and professionalism. 2nd purchase and he'll definitely be back for a 3rd






Vehicle information
Features
Reviews
Use car
I?ve been receiving emails regarding the cars, (MBZ S550 n Audi A8), that I?m currently interested in They have been updating me regarding the vehicle.
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Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $48,495 | 1 Good deal |
2024 Lexus RX 350 | $41,500 | 13 Good deals |
2023 Lexus RX 350 | $41,991 | 6 Good deals |
2021 Lexus RX 350 | $25,995 | 4 Good deals |
2019 Lexus RX 350 | $23,500 | 11 Good deals |
2017 Lexus RX 350 | $19,998 | 8 Good deals |
2016 Lexus RX 350 | $17,977 | 5 Good deals |
2015 Lexus RX 350 | $11,900 | 7 Good deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,129, with pricing starting at $28,592.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
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2022 Lexus RX 350 by city
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Lexus RX 350 trims
-
Lexus RX 350 2022 Base
20 listings starting at $30,440
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.