Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Lexus RX 350
for sale
near
Plainfield, IL
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Great service
Good customer service From day one I go over there to buy a car they was good with me they help me a lot even after one week from heaven the car I go back to them the car was shaking need break They help me and fix the brake for me and check the car from A-Z thank you for a good customer service
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Sal was our salesman and I was so happy with him.
Sal was our salesman and I was so happy with him. He was patient and answered all my many questions. We were treated so well throughout the whole process, including the loan application. No stress and the car was prepped so that it looked new. Very happy.
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.






Used
2022 Lexus RX 350
Vehicle information
Features
Reviews
Good experience fast service
I had a good experience with Chris Price awesome sales man.. no pushy sales tactics.. he was honest and straight to the point.. I have bad credit.. and was turned down from alot of different dealers Marino, Hawk,Naperville and Shermans.. all said No.. but Carmax have me thre car I wanted wth super low miles.. Thanx Chris you a good guy 🤗
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Efren my service advisor was very helpful and efficient
Efren my service advisor was very helpful and efficient he took care of everything for me
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.




Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Every experience that I have at Lexus of Orland is
Every experience that I have at Lexus of Orland is phenomenal. From Sales to Service - everyone is kind, knowledgeable, and goes the extra mile. Special shout outs to Alex A, Dave C, Chris K, Efren, Mareia, and Luis. You all are the best!
AMAZING PLACE TO SHOP!
Hi, my name is Monica, on 11/18/22. I visited the Lexus car dealership at 2600 Fulton st. in Sacramento.I had the most beautiful encounter with Angel the car salesman, Robert in finance, and Brian the store manager. They all demonstrated exceptionally great customer service going above and beyond, making sure that I walk away happy. I pull off in my brand new RX 350 Lexus. Please go and see these guys they're AMAZING!!!!!.... TO GOD BE THE GLORY!!!...






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Last week I connected through cars.
Last week I connected through cars.com with Hinsdale Land Rover had a great experience. My sales person was Agnes, she is amazing. She really took great care of me. I’m from out of state and had the whole deal worked out before I came in. The dealership is very easy to find .4 of a mile from the highway exit. I highly recommend them they are very reputable the price listed was what I paid for the car. I’m super happy with my Tesla Thanks again Agnes






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Great and friendly service.
Great and friendly service. Ri Pritchard the salesman was great and was able to get me into the car I wanted. I highly recommend this dealership.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Mercedes Benz and honestly it was the most stress free
Mercedes Benz and honestly it was the most stress free car buying experience I’ve ever had. Kimberly Quintero, in sales, was extremely patient and straight forward. She dealt with me sizing the back seats and taking calls with my wife regarding child car seats and positioning. Kimberly was the absolute best when it came to showing the vehicle and even doing research on work done by the prior owner. It was also a breath of fresh air to deal with someone who was so transparent and not aggressive at all. When it came to signing paperwork Fay Demos shocked me, she was able to beat my credit unions rate. Went in under the impression I was going through my credit union, and nope she beat it. Both Kimberly and Fay went above and beyond and definitely earned my business. I would highly recommend anyone shopping for a Mercedes, or used vehicle, to buy through them.






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Anthony greeted me in the parking lot and was friendly
Anthony greeted me in the parking lot and was friendly and professional. He quickly brought the car out that I wanted to see. Negotiations were very fair and the paperwork was done in a timely maner. I love my new/pre-owned HyundaiTucson. Thank you Anthony and the team! I'll see you again when I need my next vehicle.






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Great experience!
Great experience! Minimal hassle with price. The salesman was awesome! The vehicle I bought was in an excellent condition.






Used
2022 Lexus RX 350 F-SPORT Handling
Vehicle information
Features
Reviews
Price listed is the price you pay!
Dealt with this CarMax dealer over the phone and email. Tried to negotiate a price based on other dealers in the area for the same vehicle and was told that the price listed was the price you pay!






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Awesome experience Just bought a 2023 Jeep Grand
Awesome experience Just bought a 2023 Jeep Grand Wagoneer Sales Specialist Joe Peterson was Honest, Professional and expedited all aspects of the Purchase. Appreciate it Joe Thanks Much






Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Bought a 2025 Lexus TX from Dylan, easy process and quick
Bought a 2025 Lexus TX from Dylan, easy process and quick service for add-ons. I don’t even live in the area, but saw what I wanted on the internet. Drove it home next day.






Used
2022 Lexus RX 350 F SPORT Appearance
Vehicle information
Features
Reviews
Dean Bustami in service has been in charge of all my cars
Dean Bustami in service has been in charge of all my cars for 20 years . I wouldn’t go anywhere else
There are 20 matching cars close to your year range.






Certified
2023 Lexus RX 350 Base
Vehicle information
Features






Used
2021 Lexus RX 350 F SPORT Appearance
Vehicle information
Features






Used
2021 Lexus RX 350 Base
Vehicle information
Features




Certified
2024 Lexus RX 350 Base
Vehicle information
Features






Used
2020 Lexus RX 350 Performance
Vehicle information
Features






Certified
2024 Lexus RX 350 F SPORT Handling
Vehicle information
Features






Used
2020 Lexus RX 350 Base
Vehicle information
Features




Certified
2024 Lexus RX 350 Base
Vehicle information
Features






Used
2020 Lexus RX 350 Performance
Vehicle information
Features






Certified
2024 Lexus RX 350 Base
Vehicle information
Features






Used
2023 Lexus RX 350 Luxury
Vehicle information
Features






Used
2023 Lexus RX 350 Luxury
Vehicle information
Features






Certified
2024 Lexus RX 350 Luxury
Vehicle information
Features






Used
2024 Lexus RX 350 Premium Plus
Vehicle information
Features






Used
2024 Lexus RX 350 Premium Plus
Vehicle information
Features






Used
2024 Lexus RX 350 Base
Vehicle information
Features






Used
2024 Lexus RX 350 Premium Plus
Vehicle information
Features






Used
2024 Lexus RX 350 Base
Vehicle information
Features






Certified
2024 Lexus RX 350 Luxury
Vehicle information
Features






Vehicle information
Features
-
Prev - 1
-
Next
Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $55,399 | |
2024 Lexus RX 350 | $52,500 | 6 Good deals |
2017 Lexus RX 350 | $17,949 | 4 Good deals |
2013 Lexus RX 350 | $11,999 | 6 Good deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $42,521, with pricing starting at $28,792.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.5
- Interior 4.5
- Performance 3.8
- Value 3.5
- Exterior 4.6
- Reliability 3.9
63% of drivers recommend this car
- Comfort 4.5
- Interior 4.5
- Performance 3.8
- Value 3.5
- Exterior 4.6
- Reliability 3.9
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Similar Cars
-
Toyota Highlander for sale
24 listings starting at $30,950
Research the 2022 Lexus RX 350
Compare the 2022 Lexus RX 350
Used 2022 Lexus RX 350 by city
-
2022 Lexus RX 350 in Romeoville, IL
2 Great Deals out of 24 listings starting at $37,473
-
2022 Lexus RX 350 in Bolingbrook, IL
2 Great Deals out of 25 listings starting at $37,473
-
2022 Lexus RX 350 in Naperville, IL
1 Great Deal out of 31 listings starting at $33,995
-
2022 Lexus RX 350 in Lockport, IL
2 Great Deals out of 20 listings starting at $37,473
-
2022 Lexus RX 350 in Aurora, IL
1 Great Deal out of 27 listings starting at $33,995
-
2022 Lexus RX 350 in Woodridge, IL
2 Great Deals out of 38 listings starting at $33,995
-
2022 Lexus RX 350 in Lemont, IL
2 Great Deals out of 25 listings starting at $37,473
-
2022 Lexus RX 350 in Lisle, IL
2 Great Deals out of 38 listings starting at $33,995
-
2022 Lexus RX 350 in Warrenville, IL
1 Great Deal out of 35 listings starting at $33,995
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
Certified cars are manufacturer warrantied and typically go through a rigorous multi-point inspection.
This car is likely to sell soon based on the price, features, and condition.
${award_blurb}
${award_two_blurb}