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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class
for sale
near
Van Nuys, CA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
The BEST Mercedes-Benz dealership in Southern Cali
This dealership and service department go above and beyond in the quality of work that they do! I am a TV Executive and have very little time on my hands with all the projects I work on. I am truly grateful that this dealership works so hard to continue to make me the happy customer I am!!! Kevin Malone is the BEST service advisor I have ever worked with, and I will only do business with him! I also enjoy working Leslie for my loaner vehicles and seeing Nikki’s smiling face at the front desk! Keep up the good work team! I have referred lots of my fellow colleagues and family members to this place, and they feel the same way I do!
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰






Certified
2021 Mercedes-Benz E-Class E 350
Vehicle information
Reviews
Jesus Duarte is amazing person.
Jesus Duarte gave us amazing service ,helpful , petient to us.he gave us a good deal for bronco sports 2022 pepper red color.last October .
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
I recently purchased a Mercedes Benz Sprinter Van from
I recently purchased a Mercedes Benz Sprinter Van from Valencia Mercedes Benz Dealership, and I couldn't be more thrilled with the entire experience. Ethan Zinshteyn and Sales Manager Daniel Medina provided exceptional service from start to finish. Ethan was incredibly knowledgeable about the Sprinter Van and took the time to understand my specific needs. He patiently answered all my questions and ensured I was comfortable with my decision. His professionalism and attention to detail made the buying process smooth and enjoyable. Daniel Medina, the Sales Manager, also played a pivotal role in my purchase. He worked diligently to secure the best possible deal and went above and beyond to ensure I was satisfied with every aspect of the transaction. His commitment to customer satisfaction is truly commendable. The team at Valencia Mercedes Benz Dealership exceeded my expectations in every way. I highly recommend Ethan Zinshteyn, Daniel Medina, and the entire dealership for anyone looking to purchase a Mercedes Benz. Their dedication to excellence and customer service is unmatched!
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
Natalie was awesome.
Natalie was awesome. Professional and friendly. Service and brake pads. Suggested only front brake pads were necessary. And tire rotation. Car was clean and ready early for pickup. Have been a customer for 20 plus years.
This car is why you buy a Mercedes-Benz.
I'm replacing a 17 y/o E-320 that I loved. I am now infatuated with the New 2021 E-450 4 matic it just so happens to be the Motor Trend car of the year. Very nice exterior styling. Fantastic interior. all the latest technology and a great interior. The strait V-6 with turbo is smooth as silk. The optional Air Body control suspension makes for a fantastic smooth ride.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
Wow this is hands down the best dealership i went to.
Wow this is hands down the best dealership i went to. Usually I dread the finance part but John Hong my finance manager was a star amongst Stars! I Definitley will let everyone know about Calstar Mercedes led by Armen and company!
Love my Car
The vehicle meets all of my needs. I special ordered the vehicle with the color and leather interior I prefer. It arrived exactly the way I wanted.
Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 450
Vehicle information
Features
Reviews
Easily the best car dealership I ever been to.
Easily the best car dealership I ever been to. It was like living the office tv show with all the charming and funny workers there! From Art, John and Armen they truly are the most interesting sales group in the world!
Used
2021 Mercedes-Benz E-Class 4MATIC All-Terrain Wagon
Vehicle information
Features

Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
The salesperson, Dorsa, was very helpful in choosing the
The salesperson, Dorsa, was very helpful in choosing the right car for me. The process for final sale was handled smoothly by Tom. After the purchase, when a problem occurred, Babak in the service department organized the transaction swiftly and handed me the key to a loaner vehicle. The technicians in the back shop were spot on with diagnosis and correcting the issue in a timely manner. A Bavo Zulu (high praise) to all.
There are 20 matching cars close to your year range.






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Vehicle information
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Vehicle information
Features






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Features






Used
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Mercedes-Benz E-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz E-Class | $59,798 | 1 Good deal |
2022 Mercedes-Benz E-Class | $30,999 | 5 Good deals |
2020 Mercedes-Benz E-Class | $19,741 | 4 Good deals |
2019 Mercedes-Benz E-Class | $18,991 | 6 Good deals |
2014 Mercedes-Benz E-Class | $8,450 | 1 Good deal |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)

How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $35,365, with pricing starting at $21,726.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
Style | |
---|---|
E 350 RWD Sedan | E 350 4MATIC Sedan |
Inventory price | |
Starting at $54,250 | Starting at $56,750 |
Combined MPG | |
25 | 25 |
Engine | |
255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
Style | |||||
---|---|---|---|---|---|
E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
Inventory price | |||||
Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
Combined MPG | |||||
25 | 24 | 25 | 26 | 26 | 25 |
Engine | |||||
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
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