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Used 2022 Mercedes-Benz GLS 450 SUVs for sale near me

Filters 6 Year Model Price & payment Make Mileage Body style All filters
1 match 30 miles from 43272
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Est. $400 /mo*
Down Payment
$0
Net trade-in value
$0
Months
72
APR
7.0%
Sales tax
0.0%

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

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2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC View all 31 photos

Used

2022 Mercedes-Benz GLS 450 4MATIC

41,121 mi.
$52,598 $807 price drop
Est. $968/mo*
Free CARFAX 1-Owner Report
Mercedes-Benz of Easton
(947 reviews)
Columbus, OH (9 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Black
Int. color: Macchiato Beige
Drivetrain: All-wheel Drive
MPG: 18-24
Fuel type: Gasoline
Transmission: 9-Speed Automatic
Engine: 3.0L I6 24V GDI DOHC Turbo
Stock #: MN364242A
VIN: 4JGFF5KE8NA714714

Features

Convenience: Heated Seats, Heated Steering Wheel, Keyless Entry, Navigation System, Power Liftgate, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, Satellite Radio
Exterior: Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety: Blind Spot Monitor, Brake Assist, Lane Departure Warning, Rain Sensing Wipers, Stability Control
Seating: Leather Seats, Memory Seat, Third Row Seating

Reviews

Mercedes-Benz of Easton review

Joe Struewing at Easton Mercedes-Benz always ensures the

October 3, 2025
By Jodi from Columbus, Ohio

Joe Struewing at Easton Mercedes-Benz always ensures the service of our vehicle is handled professionally and keeps us updated on what is needed and expected costs.

2022 Mercedes-Benz GLS 450 4MATIC review

Very happy with my purchase from RBM Alpharetta.

May 10, 2024
By Jeff
Owns this car

Very happy with my purchase from RBM Alpharetta. The car has a very comfortable interior with all the features available. Handles well in town and on long drives. Good acceleration for such a big vehicle. Love the contemporary exterior.

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2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC View all 16 photos

Used

2022 Mercedes-Benz GLS 450 4MATIC

48,577 mi.
$58,859
Est. $1,084/mo*
Get the AutoCheck Report
Bob Ross Buick GMC
Dayton, OH (65 mi.)

Vehicle information

Ext. color: Black
Int. color: Black
Drivetrain: All-wheel Drive
MPG: 18-24.00
Fuel type: Gasoline
Transmission: Automatic
Engine: 3L I-6 gasoline direct injection, DOHC, variable valve control,
Stock #: P12286
VIN: 4JGFF5KE7NA695640

Features

Convenience: Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats, Memory Seat, Third Row Seating
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC View all 26 photos

Mercedes-Benz Certified

2022 Mercedes-Benz GLS 450 4MATIC

50,935 mi.
$52,233
Est. $962/mo*
Free CARFAX 1-Owner Report
Mercedes-Benz of West Chester Ohio
West Chester Township, OH (88 mi.)

Vehicle information

Ext. color: Black
Int. color: Macchiato Beige
Drivetrain: All-wheel Drive
MPG: 18-24
Fuel type: Gasoline
Transmission: 9-Speed Automatic
Engine: 3.0L I6 24V GDI DOHC Turbo
Stock #: LNA588292
VIN: 4JGFF5KE1NA588292

Features

Convenience: Heated Seats, Heated Steering Wheel, Keyless Entry, Navigation System, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, Satellite Radio
Exterior: Alloy Wheels, Roof Rack, Sunroof/Moonroof, Tow Hitch
Safety: Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats, Memory Seat, Third Row Seating
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC View all 41 photos

Mercedes-Benz Certified

2022 Mercedes-Benz GLS 450 4MATIC

31,167 mi.
$55,769 $111 price drop
Est. $1,027/mo*
Free CARFAX Report
Mercedes-Benz of Cincinnati
Cincinnati, OH (89 mi.)

Vehicle information

Ext. color: Selenite Gray Metallic
Int. color: Black
Drivetrain: All-wheel Drive
MPG: 18-24
Fuel type: Gasoline
Transmission: Automatic
Engine: 3L I-6 gasoline direct injection, DOHC, variable valve control,
Stock #: TNA629557
VIN: 4JGFF5KE9NA629557

Features

Convenience: Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats, Memory Seat, Third Row Seating
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC View all 42 photos

Mercedes-Benz Certified

2022 Mercedes-Benz GLS 450 4MATIC

44,098 mi.
$57,000
Est. $1,050/mo*
Free CARFAX 1-Owner Report
Mercedes-Benz of Cincinnati
Cincinnati, OH (89 mi.)

Vehicle information

Ext. color: Diamond White
Int. color: Macchiato Beige/Black
Drivetrain: All-wheel Drive
MPG: 18-24
Fuel type: Gasoline
Transmission: Automatic
Engine: 3L I-6 gasoline direct injection, DOHC, variable valve control,
Stock #: LNA671329
VIN: 4JGFF5KE8NA671329

Features

Convenience: Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats, Memory Seat, Third Row Seating
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC
2022 Mercedes-Benz GLS 450 4MATIC

Mercedes-Benz Certified

2022 Mercedes-Benz GLS 450 4MATIC

25,070 mi.
$60,999
Est. $1,123/mo*
Get the AutoCheck Report
Astorg Mercedes-Benz of Parkersburg
Parkersburg, WV (93 mi.)
Call

Vehicle information

Ext. color: Diamond White
Int. color: Black MB-Tex
Fuel type: Hybrid
Stock #: MX7410A
VIN: 4JGFF5KE7NA625796
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Mercedes-Benz GLS 450 prices by year

Model year Prices from Deals
2026 Mercedes-Benz GLS 450 $4,710
2025 Mercedes-Benz GLS 450 $73,486 77 Great deals
2024 Mercedes-Benz GLS 450 $59,995 70 Great deals
2023 Mercedes-Benz GLS 450 $47,888 79 Great deals
2021 Mercedes-Benz GLS 450 $29,995 55 Great deals
2020 Mercedes-Benz GLS 450 $21,999 36 Great deals
2019 Mercedes-Benz GLS 450 $11,896 53 Great deals
2018 Mercedes-Benz GLS 450 $12,499 29 Great deals
2017 Mercedes-Benz GLS 450 $10,995 60 Great deals

About the 2022 Mercedes-Benz GLS 450

Basics

4MATIC shown (base trim).

Seating
6
Door count
4
Drivetrain
All-wheel drive
Combined MPG
20
Transmission
9-Speed A/T
Engine
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)
Side view of the 2022 Mercedes-Benz GLS 450
FAQs

How much does the 2022 Mercedes-Benz GLS 450 cost?

The 2022 Mercedes-Benz GLS 450 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 GLS 450 is $52,348, with pricing starting at $32,737.

What is the MPG of the 2022 Mercedes-Benz GLS 450?

The 2022 Mercedes-Benz GLS 450 offers up to 18 MPG in city driving and 24 MPG on the highway for a combined rating of 20 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Is the 2022 Mercedes-Benz GLS 450 reliable?

The 2022 Mercedes-Benz GLS 450 has an average reliability rating of 3 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 GLS 450 owners.

Is the 2022 Mercedes-Benz GLS 450 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Mercedes-Benz GLS 450.

(2 reviews)
Rating breakdown (out of 5):
  • Comfort 4.0
  • Interior 4.0
  • Performance 3.0
  • Value 3.0
  • Exterior 4.5
  • Reliability 3.0
Ratings (2 reviews)

50% of drivers recommend this car

Rating breakdown (out of 5):
  • Comfort 4.0
  • Interior 4.0
  • Performance 3.0
  • Value 3.0
  • Exterior 4.5
  • Reliability 3.0
Trims

GLS 450 (1 style)

Style
GLS 450 4MATIC SUV
Inventory price
Starting at $77,850
Combined MPG
20
Engine
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.

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GLS 450 trims
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‡Monthly budget search results are estimated based on a 72-month loan term with $0 down payment, $0 trade-in value, 0.0% sales tax and 7.0% APR. Inputs can be personalized using the calculator.
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