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Used 2021 Mercedes-Benz S-Class for sale near me

Filters 5 Year Model Price & payment Make Mileage All filters
1 match 30 miles from 43272
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Est. $400 /mo*
Down Payment
$0
Net trade-in value
$0
Months
72
APR
7.0%
Sales tax
0.0%

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

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2021 Mercedes-Benz S-Class S 580 4MATIC
2021 Mercedes-Benz S-Class S 580 4MATIC
2021 Mercedes-Benz S-Class S 580 4MATIC
2021 Mercedes-Benz S-Class S 580 4MATIC
2021 Mercedes-Benz S-Class S 580 4MATIC
2021 Mercedes-Benz S-Class S 580 4MATIC View all 39 photos

Used

2021 Mercedes-Benz S-Class S 580 4MATIC

74,200 mi.
$56,563
Est. $1,041/mo*
Free CARFAX Report
Twins Auto of Dublin
(89 reviews)
Dublin, OH (12 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Black
Int. color: White
Drivetrain: All-wheel Drive
MPG: 17-25
Fuel type: Gasoline
Transmission: Automatic
Engine: AMG 4L V-8 gasoline direct injection, DOHC, variable valve contr
Stock #: D4710
VIN: W1K6G7GB1MA016297

Features

Convenience: Adaptive Cruise Control, Cooled Seats, Heated Seats, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating: Leather Seats, Memory Seat

Reviews

Twins Auto of Dublin review

I was very satisfied with Zaid and the rest of the staff

June 20, 2025
By Alex from Columbus, OH

I was very satisfied with Zaid and the rest of the staff at Twins Auto of Dublin. They have a great selection of used cars that tend be "higher end". Zaid was extremely knowledgeable about every brand and model. He wasn't overly pushy, which I appreciate. They were quick, painless, and fair when it came to negotiation and the financials.

2021 Mercedes-Benz S-Class S 580 4MATIC review

Love my Mercedes

April 21, 2024
By Beverly from Deering nh
Owns this car

I have been driving Mercedes Benz s class vehicles for over 10 years, traded every 3-4 years and have been very happy, always have them serviced at the dealer, always received a loaner, no complaints.

There are 5 matching cars close to your year range.

2022 Mercedes-Benz S-Class S 580 4MATIC
2022 Mercedes-Benz S-Class S 580 4MATIC
2022 Mercedes-Benz S-Class S 580 4MATIC
2022 Mercedes-Benz S-Class S 580 4MATIC
2022 Mercedes-Benz S-Class S 580 4MATIC
2022 Mercedes-Benz S-Class S 580 4MATIC View all 29 photos

Mercedes-Benz Certified

2022 Mercedes-Benz S-Class S 580 4MATIC

32,864 mi.
$78,643 $927 price drop
Est. $1,448/mo*
Free CARFAX Report
Mercedes-Benz of Easton
Columbus, OH (9 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Black
Int. color: Black
Drivetrain: All-wheel Drive
MPG: 16-25
Fuel type: Gasoline
Transmission: 9-Speed Automatic
Engine: 4.0L V8 32V GDI DOHC Twin Turbo
Stock #: MU19804
VIN: W1K6G7GB3NA075840

Features

Convenience: Adaptive Cruise Control, Heated Seats, Keyless Entry, Navigation System, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats, Memory Seat
2022 Mercedes-Benz S-Class S 500 4MATIC
2022 Mercedes-Benz S-Class S 500 4MATIC
2022 Mercedes-Benz S-Class S 500 4MATIC
2022 Mercedes-Benz S-Class S 500 4MATIC
2022 Mercedes-Benz S-Class S 500 4MATIC
2022 Mercedes-Benz S-Class S 500 4MATIC View all 29 photos

Used

2022 Mercedes-Benz S-Class S 500 4MATIC

42,347 mi.
$66,864
Est. $1,231/mo*
Free CARFAX Report
Mercedes-Benz of Easton
Columbus, OH (9 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Nautical Blue Metallic
Int. color: Silver Gray
Drivetrain: All-wheel Drive
MPG: 21-30
Fuel type: Gasoline
Transmission: 9-Speed Automatic
Engine: 3.0L I6 24V GDI DOHC Turbo
Stock #: MU19856
VIN: W1K6G6DB7NA091375

Features

Convenience: Adaptive Cruise Control, Heated Seats, Heated Steering Wheel, Keyless Entry, Navigation System, Remote Start
Entertainment: Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, Satellite Radio
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Brake Assist, Rain Sensing Wipers, Stability Control
Seating: Leather Seats, Memory Seat
2020 Mercedes-Benz S-Class S 560 4MATIC Sedan
2020 Mercedes-Benz S-Class S 560 4MATIC Sedan
2020 Mercedes-Benz S-Class S 560 4MATIC Sedan
2020 Mercedes-Benz S-Class S 560 4MATIC Sedan
2020 Mercedes-Benz S-Class S 560 4MATIC Sedan
2020 Mercedes-Benz S-Class S 560 4MATIC Sedan View all 25 photos

Used

2020 Mercedes-Benz S-Class S 560 4MATIC Sedan

168,136 mi.
$45,995
Est. $847/mo*
Free CARFAX Report
Columbus Luxury Cars
Columbus, OH (8 mi.)
Call Check availability Check availability

Vehicle information

Ext. color: Black
Int. color: Black
Drivetrain: All-wheel Drive
MPG: 17-27
Fuel type: Gasoline
Transmission: Automatic
Engine: 4L V-8 gasoline direct injection, DOHC, variable v
Stock #: 8056
VIN: WDDUG8GB0LA520805

Features

Convenience: Heated Seats, Keyless Entry, Keyless Start, Navigation System, Remote Start
Entertainment: Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, USB Port, WiFi Hotspot
Exterior: Alloy Wheels, Sunroof/Moonroof
Safety: Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Stability Control
Seating: Leather Seats, Memory Seat
2022 Mercedes-Benz S-Class S 580 4MATIC
2022 Mercedes-Benz S-Class S 580 4MATIC
2022 Mercedes-Benz S-Class S 580 4MATIC

Mercedes-Benz Certified

2022 Mercedes-Benz S-Class S 580 4MATIC

42,115 mi.
$74,985 $1,813 price drop
Est. $1,381/mo*
Get the AutoCheck Report
Crown Eurocars of Dublin
Dublin, OH (13 mi.)
Call

Vehicle information

Ext. color: Black
Int. color: Exclusive nappa leather carmine red / black
Drivetrain: All-wheel Drive
Fuel type: Hybrid
Stock #: 30P1078
VIN: W1K6G7GB8NA110937
2023 Mercedes-Benz S-Class S 500 4MATIC
2023 Mercedes-Benz S-Class S 500 4MATIC
2023 Mercedes-Benz S-Class S 500 4MATIC

Mercedes-Benz Certified

2023 Mercedes-Benz S-Class S 500 4MATIC

13,269 mi.
$77,995
Est. $1,436/mo*
Get the AutoCheck Report
Crown Eurocars of Dublin
Dublin, OH (13 mi.)
Call

Vehicle information

Ext. color: Black
Int. color: Black Nappa Leather
Drivetrain: All-wheel Drive
Fuel type: Hybrid
Stock #: 303034A
VIN: W1K6G6DB5PA193597
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Mercedes-Benz S-Class prices by year

Model year Average price Deals
2026 Mercedes-Benz S-Class $142,722
2025 Mercedes-Benz S-Class $138,799 8 Great deals
2024 Mercedes-Benz S-Class $120,961 20 Great deals
2023 Mercedes-Benz S-Class $81,603 57 Great deals
2022 Mercedes-Benz S-Class $70,557 113 Great deals
2020 Mercedes-Benz S-Class $46,153 26 Great deals
2019 Mercedes-Benz S-Class $41,193 36 Great deals
2018 Mercedes-Benz S-Class $35,852 22 Great deals
2017 Mercedes-Benz S-Class $37,235 19 Great deals

About the 2021 Mercedes-Benz S-Class

Basics

S 500 4MATIC shown (base trim).

Seating
5
Door count
4
Drivetrain
All-wheel Drive
Combined MPG
24
Transmission
9-Speed A/T
Engine
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)
Side view of the 2021 Mercedes-Benz S-Class
FAQs

How much does the 2021 Mercedes-Benz S-Class cost?

The 2021 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 S-Class is $64,902, with pricing starting at $49,885.

What is the MPG of the 2021 Mercedes-Benz S-Class?

The 2021 Mercedes-Benz S-Class offers up to 20 MPG in city driving and 29 MPG on the highway for a combined rating of 24 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Mercedes-Benz S-Class?

The 2021 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:

Is the 2021 Mercedes-Benz S-Class reliable?

The 2021 Mercedes-Benz S-Class has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 S-Class owners.

Is the 2021 Mercedes-Benz S-Class a good sedan?

Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz S-Class.

(3 reviews)
Rating breakdown (out of 5):
  • Comfort 5.0
  • Interior 5.0
  • Performance 5.0
  • Value 4.7
  • Exterior 5.0
  • Reliability 5.0
Ratings (3 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
  • Comfort 5.0
  • Interior 5.0
  • Performance 5.0
  • Value 4.7
  • Exterior 5.0
  • Reliability 5.0
Trims

S 500 (1 style)

Style
S 500 4MATIC Sedan
Inventory price
Starting at $109,800
Combined MPG
24
Engine
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

S 560 (2 styles)

Style
S 560 Cabriolet S 560 4MATIC Coupe
Inventory price
Starting at $140,000 Starting at $131,400
Combined MPG
20 20
Engine
463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) 463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel)

S 580 (1 style)

Style
S 580 4MATIC Sedan
Inventory price
Starting at $116,300
Combined MPG
20
Engine
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid)

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.

**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.

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Basics
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‡Monthly budget search results are estimated based on a 72-month loan term with $0 down payment, $0 trade-in value, 0.0% sales tax and 7.0% APR. Inputs can be personalized using the calculator.
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