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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz S-Class
for sale
near
New Brunswick, NJ
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Strange that they didn’t push insurance and extras.
Strange that they didn’t push insurance and extras. In another place they almost begged. Here - want it? fine. Don’t want? okay. Clean, calm, adult approach.
Love my Mercedes
I have been driving Mercedes Benz s class vehicles for over 10 years, traded every 3-4 years and have been very happy, always have them serviced at the dealer, always received a loaner, no complaints.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Top notch place.
Top notch place. Very easy to do business with, everyone was friendly and inviting. Looking forward to doing business with them again.
An Absolute Dream
I have owned 6 S Class (SonderKlas) cars in my life and each and every single one has been problem free and a pure joy to own, drive, and admire. The 2021 S580 however.. Well this car is truly something special and not an incremental upgrade! This thing is crazy






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Juan"s jubilant personality.
enthusiastic welcome with easy navigation of LaventeGT purchase. Juan's Innovative approach of explaining everything we wanted to know on our first curiosity visit turned in to sale. Even after sale he has demonstrated same zeal and eagerness to keep us well contented customer. Highly recommended dealership for luxury cars.
Luxury
Luxury at its best, you can’t get better than that with this price range. S 580 is the way to go, the 8 cylinders are so smooth yet so sporty. This car can be Rolls Royce luxury and lamborghini urus if it wants






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Dealership was incredibly responsive to my inquiry - they
Dealership was incredibly responsive to my inquiry - they were really great to work with. I ended up buying a car elsewhere, but J&S Autohaus was a pleasure to deal with.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I pass this dealer every day on the way to the office.
I pass this dealer every day on the way to the office. I finally decided to stop in as they have opened their doors after months of renovations. The facility looks brand new and very nice. The staff were so polite and kind. I checked out their inventory, had a pleasant chat and a delicious cappuccino. Needless to say I’m coming back this weekend with my husband to check out a gorgeous BMW that caught my eye. I can see myself in it going to brunch Sunday. Stay tuned!






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
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Reviews
Honest, friendly, knowledgeable, no pressure to purchase.
Honest, friendly, knowledgeable, no pressure to purchase... Giuseppe is the perfect ambassador for Mercedes Benz and Ray Catena






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I got new wheels from here last week, what a great
I got new wheels from here last week, what a great experience! I have never been more comfortable doing all that paperwork. I would go back in a heartbeat. Even my wife is happy with how things turned out! Thanks guys!






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
Not only was I impressed with my car buying experience,
Not only was I impressed with my car buying experience, the customer service was second to none. I was invited back as many times as needed to test drive, look or ask questions before my purchase. Thanks!!! I'll be back.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I recently purchased my 2024 Mercedes-Benz GLS 450, and
I recently purchased my 2024 Mercedes-Benz GLS 450, and once again, Ahmed Abdeldayem delivered an outstanding car-buying experience. This is the fourth car I’ve purchased from Ahmed, and every interaction has been nothing short of exceptional. Ahmed’s professionalism, transparency, and genuine commitment to customer satisfaction make him a true asset to the dealership. What keeps me coming back to this dealership, however, isn’t just the incredible sales experience—it’s the amazing service department. Chad Kaplan, my service advisor, and Annmarie Albaro, the service department manager, are simply the best in the industry. They consistently go above and beyond to ensure my vehicles are well taken care of, providing prompt, efficient, and top-tier service every single time. If you’re in the market for a Mercedes-Benz, look no further than Ray Catena. Whether it’s working with Ahmed Abdeldayem for your purchase or trusting Chad and Annmarie in the service department, you’ll experience unparalleled professionalism and care. Thank you, Ahmed, Chad, Annmarie, and the entire team, for always making my experience a memorable one!
Used
2021 Mercedes-Benz S-Class S 580 4MATIC
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Reviews
I purchased a BMW from Cartopia.
I purchased a BMW from Cartopia. Adam worked with me. He went above and beyond to accommodate me during this process. There aren't enough kind words to describe the service level I received from him. I will definitely recommend anyone looking to purchase a vehicle to go to Cartopia .






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
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Reviews
Deluxe Auto Sales specializes in high-end quality
Deluxe Auto Sales specializes in high-end quality automobiles. Their vehicles are well maintained, look new and competitively priced. I m recommend Jabir as a salesperson as he’s friendly, highly communicative, knowledgeable and transparent. Thanks for the Bronco Badlands.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I bought a used Volkswagen Touran 2014, but the condition
I bought a used Volkswagen Touran 2014, but the condition is just great. A familiar mechanic checked everything for serviceability, and the car is really in very good condition. I was delighted with the quality of service. The price is pleasant, and the credit terms are some of the most favorable I have encountered.
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2022 Mercedes-Benz S-Class S 580 4MATIC
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2023 Mercedes-Benz S-Class S 580 4MATIC
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Mercedes-Benz S-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz S-Class | $119,559 | 4 Good deals |
2023 Mercedes-Benz S-Class | $58,295 | 6 Great deals |
2022 Mercedes-Benz S-Class | $54,888 | 8 Great deals |
About the 2021 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2021 Mercedes-Benz S-Class cost?
The 2021 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 S-Class is $64,186, with pricing starting at $49,444.
What is the MPG of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class offers up to 20 MPG in city driving and 29 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz S-Class reliable?
The 2021 Mercedes-Benz S-Class has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 S-Class owners.
Is the 2021 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
100% of drivers recommend this car
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $109,800 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 560 (2 styles)
Style | |
---|---|
S 560 Cabriolet | S 560 4MATIC Coupe |
Inventory price | |
Starting at $140,000 | Starting at $131,400 |
Combined MPG | |
20 | 20 |
Engine | |
463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) | 463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $116,300 |
Combined MPG |
20 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz S-Class
Compare the 2021 Mercedes-Benz S-Class
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.