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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 GMC Sierra 2500 trucks
for sale
near
St. Charles, MO
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Services
Awesome your staff is the best I've ever !!! Will always you BELLEMANN its literally the best customer service group I've seen Worth the extra mile to get there!!!
Beautiful truck
I love my 2021 GMC Denali 2500HD. I have gotten more complements on this truck than any other vehicle that I have owned. I get great highway fuel milage average 19-26mpg,which is great for a heavy duty truck!
Used
2021 GMC Sierra 2500 Base
Vehicle information
Features
Reviews
Amanda Gillis
was looking for a new car this person ask us if they could help us , there service was outstanding and the time to get the new car was out of this world. We have called here for help and they are right there
Best truck I ever owned
Love my GMC. Owned a Chevy and this absolutely beats it hands down. Never had any issues. Inside is very comfortable and can't imagine driving anything else
Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Very Easy Process
Kenny M. helped me with the purchase and made the entire process very easy. Thank you again for all your help, I love the my new car!
GMC 2500 HD AT4
This is the first diesel I have owned. The power is amazing and I really like the room inside the cab. This truck is a beast... Love it!
Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Tim McKnight was an awesome salesman?
Tim McKnight was an awesome salesman?knowledgeable, low-pressure, and super helpful, making the process smooth and enjoyable. Jason G in finance was equally great, walking us through everything with ease and professionalism. Highly recommend this team for a top-notch, stress-free buying experience!
Never had one. Always wanted one and love it.
I love my Denali. Beautiful truck inside out. When I drive down the road all heads turn. I couldn't have made a better choice. That's Cortez for you good service.
Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Josh Roseke was very accommodating, professional and
Josh Roseke was very accommodating, professional and accurate. He ensured the experience was painless and efficient. The dealership should be proud to employ an associate of his caliber.
Early to tell truck has less than 100 miles
Truck was bought specifically to our travel trailer. We have to wait for 1000 break in before we can tow the trailer. So far the truck is very quiet, smooth running, & comfortable to drive. We were pleasantly surprised at how much interior storage space is available. Having the bed steps before rear tires and in the bumper sides is very nice. Bed rails are even with my shoulders so the steps get used a lot.
GMC Certified
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
I had a good experience buying my new truck through
I had a good experience buying my new truck through Laura. John Touchette was a great salesman throughout the process. Laura provided financing that got me the truck i wanted at a fair price with good interest rate! The whole signing and pickup at the dealership took about an hour. Thanks Laura
GMC Certified
2021 GMC Sierra 2500 AT4
Vehicle information
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Reviews
Josh Roseke, my sales rep was fantastic!
Josh Roseke, my sales rep was fantastic! He found me the exact SUV package I wanted and I love it!!! Michael in finance was great too!!
Used
2021 GMC Sierra 2500 AT4
Vehicle information
Features
Reviews
Easy to deal with.
Easy to deal with. Texas was very knowledgeable and caring and listened to my needs. Fast easy process highly recommend! Great place to do business!
Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
BRANDON WAS AWESOME!
Brandon did a great job! He was very helpful with getting me into my new Mustang! Thanks so much Brandon! I live my new car! 😄
Used
2021 GMC Sierra 2500 SLT
Vehicle information
Features
Reviews
Great Dealership To Work With
Dave (Internet Sales Manager) was amazing to work with. Drove over 330 miles and when I arrived at the dealership my family and I were treated amazing. The car was ready for me and set inside since it was a rainy day. Found the car of my dreams online and within 48 hours had the keys in my hand. Thank you, Jim Trenary Ford!
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GMC Sierra 2500 prices by year
| Model year | Average price | Deals |
|---|---|---|
| 2026 GMC Sierra 2500 | $81,919 | |
| 2025 GMC Sierra 2500 | $73,373 | 12 Good deals |
| 2024 GMC Sierra 2500 | $66,153 | 14 Good deals |
About the 2021 GMC Sierra 2500
Base shown (base trim).
- Seating
- 3
- Door count
- 2
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 0
- Transmission
- 6-Speed A/T
- Engine
- 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel)
How much does the 2021 GMC Sierra 2500 cost?
The 2021 GMC Sierra 2500 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 Sierra 2500 is $50,765, with pricing starting at $23,797.
What are some similar vehicles and competitors of the 2021 GMC Sierra 2500?
The 2021 GMC Sierra 2500 compares to and/or competes against the following vehicles:
Is the 2021 GMC Sierra 2500 reliable?
The 2021 GMC Sierra 2500 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 Sierra 2500 owners.
Is the 2021 GMC Sierra 2500 a good truck?
Below are the Cars.com consumer ratings for the 2021 GMC Sierra 2500.
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
75% of drivers recommend this car
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
AT4 (2 styles)
| Style | |
|---|---|
| 4WD Crew Cab 172" AT4 | 4WD Crew Cab 159" AT4 |
| Inventory price | |
| Starting at $59,300 | Starting at $59,100 |
| Combined MPG | |
| 0 | 0 |
| Engine | |
| 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Base (10 styles)
| Style | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 4WD Crew Cab 159" | 2WD Crew Cab 172" | 4WD Crew Cab 172" | 2WD Crew Cab 159" | 2WD Double Cab 162" | 4WD Double Cab 162" | 4WD Double Cab 149" | 2WD Double Cab 149" | 2WD Reg Cab 142" | 4WD Reg Cab 142" |
| Inventory price | |||||||||
| Starting at $43,400 | Starting at $40,800 | Starting at $43,600 | Starting at $40,600 | Starting at $39,000 | Starting at $41,800 | Starting at $41,600 | Starting at $38,800 | Starting at $36,200 | Starting at $39,000 |
| Combined MPG | |||||||||
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Engine | |||||||||
| 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Denali (2 styles)
| Style | |
|---|---|
| 4WD Crew Cab 172" Denali | 4WD Crew Cab 159" Denali |
| Inventory price | |
| Starting at $65,700 | Starting at $65,500 |
| Combined MPG | |
| 0 | 0 |
| Engine | |
| 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLE (10 styles)
| Style | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 2WD Crew Cab 172" SLE | 4WD Crew Cab 159" SLE | 2WD Crew Cab 159" SLE | 4WD Crew Cab 172" SLE | 2WD Double Cab 162" SLE | 2WD Double Cab 149" SLE | 4WD Double Cab 149" SLE | 4WD Double Cab 162" SLE | 4WD Reg Cab 142" SLE | 2WD Reg Cab 142" SLE |
| Inventory price | |||||||||
| Starting at $45,600 | Starting at $48,200 | Starting at $45,400 | Starting at $48,400 | Starting at $43,800 | Starting at $43,600 | Starting at $46,400 | Starting at $46,600 | Starting at $44,400 | Starting at $41,600 |
| Combined MPG | |||||||||
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Engine | |||||||||
| 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLT (8 styles)
| Style | |||||||
|---|---|---|---|---|---|---|---|
| 4WD Double Cab 162" SLT | 2WD Double Cab 149" SLT | 2WD Double Cab 162" SLT | 4WD Double Cab 149" SLT | 4WD Crew Cab 159" SLT | 2WD Crew Cab 159" SLT | 2WD Crew Cab 172" SLT | 4WD Crew Cab 172" SLT |
| Inventory price | |||||||
| Starting at $54,600 | Starting at $51,600 | Starting at $51,800 | Starting at $54,400 | Starting at $56,200 | Starting at $53,400 | Starting at $53,600 | Starting at $56,400 |
| Combined MPG | |||||||
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Engine | |||||||
| 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 GMC Sierra 2500
Compare the 2021 GMC Sierra 2500
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
