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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 GMC Sierra 2500 trucks
for sale
near
Thornton, CO
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Angel R was great.
Angel R was great. It was a smooth process. Would recommend dealer and the dealership
Beautiful truck
I love my 2021 GMC Denali 2500HD. I have gotten more complements on this truck than any other vehicle that I have owned. I get great highway fuel milage average 19-26mpg,which is great for a heavy duty truck!






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Foundation Cadillac did it again—and honestly, I’m not
Foundation Cadillac did it again—and honestly, I’m not surprised! When my 12V battery died on my Cadillac Lyriq, David Hann and his incredible team jumped into action. They did whatever it took to get me back on the road quickly and stress-free. David is truly amazing—always professional, caring, and reliable. If you’re ever in need of service, repairs, or even looking to make a purchase, go to Foundation Cadillac and ask for David. You’ll be in great hands!
Best truck I ever owned
Love my GMC. Owned a Chevy and this absolutely beats it hands down. Never had any issues. Inside is very comfortable and can't imagine driving anything else






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Carlos at Super Auto was professional, patient, and easy
Carlos at Super Auto was professional, patient, and easy to work with. He addressed my concerns and showed me several cars without being pushy. I appreciated his approach.
GMC 2500 HD AT4
This is the first diesel I have owned. The power is amazing and I really like the room inside the cab. This truck is a beast... Love it!






Used
2021 GMC Sierra 2500 AT4
Vehicle information
Features
Reviews
Always a pleasure to get my truck serviced at Mike
Always a pleasure to get my truck serviced at Mike maroone Chevrolet, gmc, Longmont. Joe was my service advisor and got my truck in and serviced a lot faster then i expected. Service was an awesome. Thank yous
Never had one. Always wanted one and love it.
I love my Denali. Beautiful truck inside out. When I drive down the road all heads turn. I couldn't have made a better choice. That's Cortez for you good service.






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Yamile was knowledgeable, professional, empathetic and a
Yamile was knowledgeable, professional, empathetic and a terrific asset for you. She is a keeper!!! I could not be more pleased with the service she provided.
Early to tell truck has less than 100 miles
Truck was bought specifically to our travel trailer. We have to wait for 1000 break in before we can tow the trailer. So far the truck is very quiet, smooth running, & comfortable to drive. We were pleasantly surprised at how much interior storage space is available. Having the bed steps before rear tires and in the bumper sides is very nice. Bed rails are even with my shoulders so the steps get used a lot.






Used
2021 GMC Sierra 2500 SLT
Vehicle information
Features
Reviews
The best experience I’ve ever had in purchasing a car!
The best experience I’ve ever had in purchasing a car! Dan gave us an incredible deal, and Chris was amazing to work with. I highly recommend Lyn Lyall Chevrolet!





Used
2021 GMC Sierra 2500 AT4
Vehicle information
Features
Reviews
I'm so excited about my Chevy, Equinox, and so blessed my
I'm so excited about my Chevy, Equinox, and so blessed my friend referred me to Leon and his team!! I was able to get a affordable, trustworthy, safe car for myself and my kids! It’s sleek and comfortable! I couldn't be happy with Rocky Mountain Eurosport in Parker!! I will definitely be referring friends and family members here!


Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
DJ was my salesman and he did an amazing job!
DJ was my salesman and he did an amazing job! I highly recommend going to Alpine Buick. The Facility is beautifully represented. Always eager to help.






Used
2021 GMC Sierra 2500 AT4
Vehicle information
Features
Reviews
Everyone was very friendly and kind.
Everyone was very friendly and kind. Always keep in the loop of what was going on. Was not to long process to complete the whole process.






Used
2021 GMC Sierra 2500 Base
Vehicle information
Features
Reviews
Great experience
We purchased our Ford F350 about a month ago for a great price with absolutely no pressure or hassles from anybody there. They took our old F150 in trade and delivered the new truck down to Colorado Springs. Mike replaced the cracked windshield before delivery which we hadn't asked for or expected, which was awesome. Already put a hard 5,000 miles on it pulling a very heavy 5th wheel RV trailor in a across country move. The truck performed great and we absolutely love it!






Used
2021 GMC Sierra 2500 SLT
Vehicle information
Features
Reviews
Had a great experience buying my Tacoma from Karina and
Had a great experience buying my Tacoma from Karina and Juan! Easy process and excellent service.






Used
2021 GMC Sierra 2500 Denali
Vehicle information
Features
Reviews
Annissa Medina has helped me so much taken care of
Annissa Medina has helped me so much taken care of everything for me and is always so sweet, understanding, and very helpful with everything that I’ve needed. Her communication skills and personality along with professionalism always reassure me that I am going to get the best service and make me feel like I am always welcomed.
There are 20 matching cars close to your year range.






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GMC Sierra 2500 prices by year
Model year | Prices from | Deals |
---|---|---|
2026 GMC Sierra 2500 | $58,284 | |
2025 GMC Sierra 2500 | $51,430 | |
2024 GMC Sierra 2500 | $49,966 | 12 Good deals |
2022 GMC Sierra 2500 | $33,988 | 13 Good deals |
About the 2021 GMC Sierra 2500
Base shown (base trim).
- Seating
- 3
- Door count
- 2
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 0
- Transmission
- 6-Speed A/T
- Engine
- 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel)

How much does the 2021 GMC Sierra 2500 cost?
The 2021 GMC Sierra 2500 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 Sierra 2500 is $53,359, with pricing starting at $26,397.
What are some similar vehicles and competitors of the 2021 GMC Sierra 2500?
The 2021 GMC Sierra 2500 compares to and/or competes against the following vehicles:
Is the 2021 GMC Sierra 2500 reliable?
The 2021 GMC Sierra 2500 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 Sierra 2500 owners.
Is the 2021 GMC Sierra 2500 a good truck?
Below are the Cars.com consumer ratings for the 2021 GMC Sierra 2500.
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
75% of drivers recommend this car
- Comfort 4.7
- Interior 4.6
- Performance 4.3
- Value 3.9
- Exterior 4.6
- Reliability 4.0
AT4 (2 styles)
Style | |
---|---|
4WD Crew Cab 172" AT4 | 4WD Crew Cab 159" AT4 |
Inventory price | |
Starting at $59,300 | Starting at $59,100 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Base (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
4WD Crew Cab 159" | 2WD Crew Cab 172" | 4WD Crew Cab 172" | 2WD Crew Cab 159" | 2WD Double Cab 162" | 4WD Double Cab 162" | 4WD Double Cab 149" | 2WD Double Cab 149" | 2WD Reg Cab 142" | 4WD Reg Cab 142" |
Inventory price | |||||||||
Starting at $43,400 | Starting at $40,800 | Starting at $43,600 | Starting at $40,600 | Starting at $39,000 | Starting at $41,800 | Starting at $41,600 | Starting at $38,800 | Starting at $36,200 | Starting at $39,000 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
Denali (2 styles)
Style | |
---|---|
4WD Crew Cab 172" Denali | 4WD Crew Cab 159" Denali |
Inventory price | |
Starting at $65,700 | Starting at $65,500 |
Combined MPG | |
0 | 0 |
Engine | |
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLE (10 styles)
Style | |||||||||
---|---|---|---|---|---|---|---|---|---|
2WD Crew Cab 172" SLE | 4WD Crew Cab 159" SLE | 2WD Crew Cab 159" SLE | 4WD Crew Cab 172" SLE | 2WD Double Cab 162" SLE | 2WD Double Cab 149" SLE | 4WD Double Cab 149" SLE | 4WD Double Cab 162" SLE | 4WD Reg Cab 142" SLE | 2WD Reg Cab 142" SLE |
Inventory price | |||||||||
Starting at $45,600 | Starting at $48,200 | Starting at $45,400 | Starting at $48,400 | Starting at $43,800 | Starting at $43,600 | Starting at $46,400 | Starting at $46,600 | Starting at $44,400 | Starting at $41,600 |
Combined MPG | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
SLT (8 styles)
Style | |||||||
---|---|---|---|---|---|---|---|
4WD Double Cab 162" SLT | 2WD Double Cab 149" SLT | 2WD Double Cab 162" SLT | 4WD Double Cab 149" SLT | 4WD Crew Cab 159" SLT | 2WD Crew Cab 159" SLT | 2WD Crew Cab 172" SLT | 4WD Crew Cab 172" SLT |
Inventory price | |||||||
Starting at $54,600 | Starting at $51,600 | Starting at $51,800 | Starting at $54,400 | Starting at $56,200 | Starting at $53,400 | Starting at $53,600 | Starting at $56,400 |
Combined MPG | |||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engine | |||||||
445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) | 445.0-hp, 6.6-liter, 8 Cylinder Engine (Diesel Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 GMC Sierra 2500
Compare the 2021 GMC Sierra 2500
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.