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  • White 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F Sport

    $33,991

    61,623 mi.
    Est. $620/mo

    Miami Lakes Automall - Chevrolet Kia Dodge Chrysler Jeep Ram Mitsubishi

    3.6
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    Hialeah, FL (5 mi)

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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $28,988

    84,448 mi.
    Est. $529/mo

    Acura of Pembroke Pines

    4.7
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    Pembroke Pines, FL (11 mi)
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  • Gray 2021 Lexus IS 350 F SportGray 2021 Lexus IS 350 F SportGray 2021 Lexus IS 350 F SportGray 2021 Lexus IS 350 F SportGray 2021 Lexus IS 350 F SportGray 2021 Lexus IS 350 F Sport

    $34,957

    50,663 mi.
    Est. $638/mo

    Sawgrass INFINITI

    4.7
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    Tamarac, FL (23 mi)
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  • White 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F Sport

    $33,991

    61,623 mi.
    Est. $620/mo

    NowCar - Delivery from Miami, Fl for Orlando Fl

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    Miami Lakes, FL (5 mi)
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  • Ultra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F Sport

    $36,991

    25,044 mi.
    Est. $675/mo

    Lexus of West Kendall

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    Miami, FL (18 mi)
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  • Blue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 Base

    $32,800

    46,317 mi.
    Est. $598/mo

    Elite Auto Auctions

    3.6
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    Hollywood, FL (15 mi)
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  • Iridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 Base

    $40,987

    $1K
    9,679 mi.
    Est. $748/mo

    AutoNation Ford Margate

    4.7
    Check Availability
    Margate, FL (28 mi)
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  • Silver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 Base

    $33,990

    42,075 mi.
    Est. $620/mo

    Bomnin Chevrolet West Kendall

    4.9
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    Miami, FL (18 mi)
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  • Atomic Silver 2021 Lexus IS 350 F SportAtomic Silver 2021 Lexus IS 350 F SportAtomic Silver 2021 Lexus IS 350 F SportAtomic Silver 2021 Lexus IS 350 F SportAtomic Silver 2021 Lexus IS 350 F SportAtomic Silver 2021 Lexus IS 350 F Sport

    $35,880

    $110
    18,781 mi.
    Est. $655/mo

    Lorenzo Ford

    4.5
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    Homestead, FL (29 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $37,995

    $500
    28,932 mi.
    Est. $693/mo

    Ambar Motors

    3.2
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    Doral, FL (4 mi)
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  • Atomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 Base

    $34,998

    57,720 mi.
    Est. $638/mo

    Lexus of Tampa Bay

    4.5
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    Free delivery from Tampa, FL (201 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $34,995

    50,300 mi.
    Est. $638/mo

    Lexus of Palm Beach

    4.8
    Check Availability
    Free delivery from West Palm Beach, FL (59 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $34,995

    50,300 mi.
    Est. $638/mo

    Lexus of Palm Beach

    4.8
    Check Availability
    West Palm Beach, FL (59 mi)
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  • Cloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F Sport

    $32,100

    $1.4K
    84,766 mi.
    Est. $586/mo

    Nissan of Vero Beach

    4.5
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    Vero Beach, FL (122 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $36,440

    43,843 mi.
    Est. $665/mo

    AutoNation USA Fort Myers

    4.4
    Check Availability
    Fort Myers, FL (108 mi)
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  • Cloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 Base

    $37,995

    $1.5K
    48,673 mi.
    Est. $693/mo

    Lexus of Fort Myers

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    Fort Myers, FL (108 mi)
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  • Ultra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F Sport

    $34,988

    44,616 mi.
    Est. $638/mo

    King Hyundai

    4.5
    Check Availability
    Deerfield Beach, FL (33 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $52,532
2025 Lexus IS 350 $46,362 9 Good deals
2024 Lexus IS 350 $41,491 5 Great deals
2023 Lexus IS 350 $41,131 17 Good deals

About the 2021 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus IS 350
FAQs

How much does the 2021 Lexus IS 350 cost?

The 2021 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 IS 350 is $35,728, with pricing starting at $25,995.

What is the MPG of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus IS 350 reliable?

The 2021 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 IS 350 owners.

Is the 2021 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2021 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $42,950 Starting at $44,950
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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