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  • Cloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 Base

    $34,595

    32,666 mi.
    Est. $631/mo

    747 Motors

    3.9
    Check Availability
    Plantation, FL (16 mi)
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  • Atomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 Base

    $40,898

    $900
    24,265 mi.
    Est. $746/mo

    Lexus of Pembroke Pines

    4.7
    Check Availability
    Pembroke Pines, FL (10 mi)
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  • Cloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 Base

    $39,898

    $500
    29,722 mi.
    Est. $728/mo

    Lexus of Pembroke Pines

    4.7
    Check Availability
    Pembroke Pines, FL (10 mi)
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  • Atomic Silver 2022 Lexus IS 350 F SportAtomic Silver 2022 Lexus IS 350 F SportAtomic Silver 2022 Lexus IS 350 F SportAtomic Silver 2022 Lexus IS 350 F SportAtomic Silver 2022 Lexus IS 350 F SportAtomic Silver 2022 Lexus IS 350 F Sport

    $40,890

    22,730 mi.
    Est. $746/mo

    Lexus of West Kendall

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    Miami, FL (21 mi)
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  • Caviar 2022 Lexus IS 350 F SportCaviar 2022 Lexus IS 350 F SportCaviar 2022 Lexus IS 350 F SportCaviar 2022 Lexus IS 350 F SportCaviar 2022 Lexus IS 350 F SportCaviar 2022 Lexus IS 350 F Sport

    $39,137

    29,622 mi.
    Est. $714/mo

    Lexus of Kendall

    2.8
    Check Availability
    Miami, FL (17 mi)
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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $36,992

    $499
    35,330 mi.
    Est. $675/mo

    AutoNation Ford Miami

    4.8
    Check Availability
    Hialeah, FL (3 mi)
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  • Not Priced

    29,567 mi.
    Est. $0/mo

    Lexus of North Miami

    4.6
    Check Availability
    North Miami, FL (7 mi)
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  • Ultra White 2022 Lexus IS 350 Base

    $39,998

    39,764 mi.
    Est. $730/mo

    Lexus of North Miami

    4.6
    Check Availability
    North Miami, FL (7 mi)
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  • Not Priced

    51,347 mi.
    Est. $0/mo

    Lexus of Pembroke Pines

    4.7
    Check Availability
    Pembroke Pines, FL (10 mi)
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  • Iridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 Base

    $43,999

    $800
    15,675 mi.
    Est. $803/mo

    Lexus of Tampa Bay

    4.5
    Check Availability
    Free delivery from Tampa, FL (201 mi)
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  • Silver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-Sport

    $36,998

    41,273 mi.
    Est. $675/mo

    CarMax Orlando

    Check Availability
    $99 delivery to Miami Lakes, FL (3 mi)
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  • Silver 2022 Lexus IS 350 IS 350 F SPORTSilver 2022 Lexus IS 350 IS 350 F SPORTSilver 2022 Lexus IS 350 IS 350 F SPORTSilver 2022 Lexus IS 350 IS 350 F SPORTSilver 2022 Lexus IS 350 IS 350 F SPORTSilver 2022 Lexus IS 350 IS 350 F SPORT

    $39,600

    $389
    30,876 mi.
    Est. $722/mo

    Napleton's Volkswagen of Orlando

    3.9
    Check Availability
    Orlando, FL (193 mi)
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  • Silver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-SportSilver 2022 Lexus IS 350 F-Sport

    $36,998

    41,273 mi.
    Est. $675/mo

    CarMax Orlando

    Check Availability
    Orlando, FL (189 mi)
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  • Atomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 Base

    $35,199

    20,192 mi.
    Est. $642/mo

    Florida Fine Cars WPB

    4.8
    Check Availability
    West Palm Beach, FL (56 mi)
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  • Iridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 Base

    $39,500

    $500
    17,995 mi.
    Est. $721/mo

    Audi Stuart

    4.7
    Check Availability
    Stuart, FL (87 mi)
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  • Iridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 Base

    $37,989

    36,451 mi.
    Est. $693/mo

    VIP Auto Enterprise 2

    Check Availability
    Orlando, FL (194 mi)
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  • $37,712

    38,418 mi.
    Est. $688/mo

    Universal Genesis

    4.2
    Check Availability
    ORLANDO, FL (185 mi)
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  • $36,778

    50,701 mi.
    Est. $671/mo

    Crown Volvo Cars

    4.9
    Check Availability
    St Petersburg, FL (200 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $52,412
2025 Lexus IS 350 $46,381 5 Great deals
2024 Lexus IS 350 $41,766 18 Good deals
2023 Lexus IS 350 $41,233 16 Good deals
2021 Lexus IS 350 $35,152 6 Good deals

About the 2022 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus IS 350
FAQs

How much does the 2022 Lexus IS 350 cost?

The 2022 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 IS 350 is $39,426, with pricing starting at $28,490.

What is the MPG of the 2022 Lexus IS 350?

The 2022 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus IS 350?

The 2022 Lexus IS 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus IS 350 reliable?

The 2022 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 IS 350 owners.

Is the 2022 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2022 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
4.5
Interior
4.5
Performance
4.5
Value
4.0
Exterior
4.5
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.5
Interior
4.5
Performance
4.5
Value
4.0
Exterior
4.5
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $43,550 Starting at $45,550
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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