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  • Cloudburst Gray 2026 Lexus IS 350 Base

    $59,418

    $769

    MSRP $59,418

    Est. $1,024/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Cloudburst Gray 2026 Lexus IS 350 Base

    $53,648

    $769

    MSRP $53,648

    Est. $924/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Infra-Red 2026 Lexus IS 350 Base

    $59,993

    $769

    MSRP $59,993

    Est. $1,034/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Caviar 2026 Lexus IS 350 Base

    $55,858

    $769

    MSRP $55,858

    Est. $963/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Caviar 2026 Lexus IS 350 Base

    $49,707

    $769

    MSRP $49,707

    Est. $857/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • cloudburst gray 2026 Lexus IS 350 Base

    $59,108

    $769

    MSRP $59,108

    Est. $1,019/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Infra-Red 2026 Lexus IS 350 Base

    $56,453

    $769

    MSRP $56,453

    Est. $973/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • caviar 2026 Lexus IS 350 Base

    $58,797

    $769

    MSRP $58,797

    Est. $1,013/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • $56,422

    $769

    MSRP $56,422

    Est. $972/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • $50,399

    $769

    MSRP $50,399

    Est. $868/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • $50,708

    $769

    MSRP $50,708

    Est. $874/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • $55,827

    $769

    MSRP $55,827

    Est. $962/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • $55,888

    $769

    MSRP $55,888

    Est. $963/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • $59,367

    $769

    MSRP $59,367

    Est. $1,023/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • $58,918

    MSRP $58,918

    Est. $1,015/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Not Priced

    Est. $0/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Gray 2026 Lexus IS 350 F-SportGray 2026 Lexus IS 350 F-SportGray 2026 Lexus IS 350 F-SportGray 2026 Lexus IS 350 F-SportGray 2026 Lexus IS 350 F-SportGray 2026 Lexus IS 350 F-Sport

    $55,998

    960 mi.
    Est. $965/mo

    CarMax Birmingham

    Check Availability
    $199 delivery to Greenville, SC (25 mi)
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  • Black 2026 Lexus IS 350 F-SportBlack 2026 Lexus IS 350 F-SportBlack 2026 Lexus IS 350 F-SportBlack 2026 Lexus IS 350 F-SportBlack 2026 Lexus IS 350 F-SportBlack 2026 Lexus IS 350 F-Sport

    $56,998

    2,278 mi.
    Est. $982/mo

    CarMax College Station

    4.7
    Check Availability
    $899 delivery to Greenville, SC (25 mi)
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  • White 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 Base

    $55,320

    MSRP $52,878

    Est. $953/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
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  • Silver 2026 Lexus IS 350 Base

    $57,496

    MSRP $55,054

    Est. $991/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
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  • Black 2026 Lexus IS 350 Base

    $55,021

    MSRP $52,579

    Est. $948/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
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  • Gray 2026 Lexus IS 350 Base

    $52,451

    MSRP $50,009

    Est. $904/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
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  • Silver 2026 Lexus IS 350 Base

    $52,451

    MSRP $50,009

    Est. $904/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view
  • Gray 2026 Lexus IS 350 Base

    $52,451

    MSRP $50,009

    Est. $904/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view
  • White 2026 Lexus IS 350 Base

    $52,350

    MSRP $49,908

    Est. $902/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view
  • White 2026 Lexus IS 350 Base

    $52,451

    MSRP $50,009

    Est. $904/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view
  • White 2026 Lexus IS 350 Base

    $52,451

    MSRP $50,009

    Est. $904/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view
  • White 2026 Lexus IS 350 Base

    $52,096

    MSRP $49,654

    Est. $898/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view
  • White 2026 Lexus IS 350 Base

    $55,521

    MSRP $53,079

    Est. $957/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view
  • Red 2026 Lexus IS 350 Base

    $61,736

    MSRP $59,294

    Est. $1,064/mo

    Jim Hudson Lexus Columbia

    5.0
    Check Availability
    Columbia, SC (96 mi)
    Quick view

About the 2026 Lexus IS 350

Basics

F SPORT Design shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
22
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2026 Lexus IS 350
FAQs

How much does the 2026 Lexus IS 350 cost?

The 2026 Lexus IS 350 price depends on trim level and optional features. Prices typically start at $45,500 and go as high as $49,950 for fully loaded models.

What is the MPG of the 2026 Lexus IS 350?

The 2026 Lexus IS 350 offers up to 19 MPG in city driving and 27 MPG on the highway for a combined rating of 22 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $47,950 Starting at $49,950
Combined MPG
22 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

IS 350 F SPORT Design (2 styles)

Style
IS 350 F SPORT Design RWD IS 350 F SPORT Design AWD
Inventory price
Starting at $45,500 Starting at $47,500
Combined MPG
22 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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