Skip to main content
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed
Skip to Filters
  • Infra Red 2025 Lexus IS 350 F SPORT DesignInfra Red 2025 Lexus IS 350 F SPORT DesignInfra Red 2025 Lexus IS 350 F SPORT DesignInfra Red 2025 Lexus IS 350 F SPORT DesignInfra Red 2025 Lexus IS 350 F SPORT DesignInfra Red 2025 Lexus IS 350 F SPORT Design

    $48,480

    2,203 mi.
    Est. $882/mo

    Ken Wilson Ford

    4.9
    Check Availability
    Canton, NC (20 mi)
    Quick view
  • Atomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 Base

    $37,998

    56,806 mi.
    Est. $692/mo

    Nissan of Hendersonville

    2.5
    Check Availability
    Hendersonville, NC (11 mi)
    Quick view
  • Ultra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 Base

    $42,995

    11,134 mi.
    Est. $782/mo

    Impex Auto Sales

    4.8
    Check Availability
    $200 delivery from Greensboro, NC (157 mi)
    Quick view
  • Silver 2023 Lexus IS 350 F-SportSilver 2023 Lexus IS 350 F-SportSilver 2023 Lexus IS 350 F-SportSilver 2023 Lexus IS 350 F-SportSilver 2023 Lexus IS 350 F-SportSilver 2023 Lexus IS 350 F-Sport

    $45,998

    12,267 mi.
    Est. $837/mo

    CarMax Savannah

    Check Availability
    $99 delivery to Asheville, NC (8 mi)
    Quick view
  • Caviar 2023 Lexus IS 350 BaseCaviar 2023 Lexus IS 350 BaseCaviar 2023 Lexus IS 350 BaseCaviar 2023 Lexus IS 350 BaseCaviar 2023 Lexus IS 350 BaseCaviar 2023 Lexus IS 350 Base

    $45,992

    13,200 mi.
    Est. $837/mo

    Toyota of Greenville

    4.7
    Check Availability
    Greenville, SC (44 mi)
    Quick view
  • Ultra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 Base

    $46,998

    13,648 mi.
    Est. $855/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (44 mi)
    Quick view
  • Infrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 Base

    $42,998

    $1K
    45,941 mi.
    Est. $783/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (44 mi)
    Quick view
  • Infrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 Base

    $45,998

    $400
    22,761 mi.
    Est. $837/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (44 mi)
    Quick view
  • iridium 2025 Lexus IS 350 Baseiridium 2025 Lexus IS 350 Baseiridium 2025 Lexus IS 350 Baseiridium 2025 Lexus IS 350 Baseiridium 2025 Lexus IS 350 Baseiridium 2025 Lexus IS 350 Base

    $48,998

    12,574 mi.
    Est. $892/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (44 mi)
    Quick view
  • Silver 2016 Lexus IS 350 BaseSilver 2016 Lexus IS 350 BaseSilver 2016 Lexus IS 350 BaseSilver 2016 Lexus IS 350 BaseSilver 2016 Lexus IS 350 BaseSilver 2016 Lexus IS 350 Base

    $21,900

    104,306 mi.
    Est. $399/mo

    Spruce Pine Chevrolet GMC

    4.7
    Check Availability
    Spruce Pine, NC (42 mi)
    Quick view
  • Ultra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 Base

    $44,998

    $1K
    19,836 mi.
    Est. $819/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (44 mi)
    Quick view
  • ultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Base

    $47,812

    $608
    3,262 mi.
    Est. $870/mo

    Forest City Honda

    4.8
    Check Availability
    Forest City, NC (37 mi)
    Quick view
  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $40,598

    $1K
    37,942 mi.
    Est. $739/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (44 mi)
    Quick view
  • Infrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 BaseInfrared 2023 Lexus IS 350 Base

    $43,998

    $600
    23,956 mi.
    Est. $801/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (44 mi)
    Quick view

About the Lexus IS 350

FAQs

How much does the Lexus IS 350 cost?

The Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the IS 350 is $38,109, with pricing starting at $4,480.

What is the MPG of the Lexus IS 350?

The Lexus IS 350 with traditional internal combustion engine offers up to 20 MPG city and 28 MPG highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus IS 350?

The Lexus IS 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus IS 350?

The Lexus IS 350 is available in the following trim levels:

What model years are available for the Lexus IS 350?

Available model years for Lexus IS 350 inventory range from 2021 to 2025.

Skip to Listings
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed