Skip to main content
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed
Skip to Filters
  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $38,660

    $838
    29,699 mi.
    Est. $705/mo

    AutoNation Toyota Pinellas Park

    4.8
    Check Availability
    Free delivery from Pinellas Park, FL (114 mi)
    Quick view
  • incognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Base

    $45,989

    $509
    2,327 mi.
    Est. $839/mo

    Lexus of Tampa Bay

    4.5
    Check Availability
    Free delivery from Tampa, FL (112 mi)
    Quick view
  • Blue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-Sport

    $35,998

    55,187 mi.
    Est. $657/mo

    CarMax Ft. Myers

    Check Availability
    Fort Myers, FL (46 mi)
    Quick view
  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $36,440

    43,843 mi.
    Est. $665/mo

    AutoNation USA Fort Myers

    4.4
    Check Availability
    Fort Myers, FL (45 mi)
    Quick view
  • cloudburst gray 2025 Lexus IS 350 Basecloudburst gray 2025 Lexus IS 350 Basecloudburst gray 2025 Lexus IS 350 Basecloudburst gray 2025 Lexus IS 350 Basecloudburst gray 2025 Lexus IS 350 Basecloudburst gray 2025 Lexus IS 350 Base

    $45,994

    13,118 mi.
    Est. $839/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view
  • Infrared 2024 Lexus IS 350 BaseInfrared 2024 Lexus IS 350 BaseInfrared 2024 Lexus IS 350 BaseInfrared 2024 Lexus IS 350 BaseInfrared 2024 Lexus IS 350 BaseInfrared 2024 Lexus IS 350 Base

    $44,994

    $600
    30,919 mi.
    Est. $821/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view
  • ultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Base

    $50,994

    $500
    16,985 mi.
    Est. $930/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view
  • Iridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 Base

    $47,994

    $500
    7,620 mi.
    Est. $876/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view
  • Iridium 2023 Lexus IS 350 BaseIridium 2023 Lexus IS 350 BaseIridium 2023 Lexus IS 350 BaseIridium 2023 Lexus IS 350 BaseIridium 2023 Lexus IS 350 BaseIridium 2023 Lexus IS 350 Base

    $40,994

    $1K
    38,373 mi.
    Est. $748/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view
  • Incognito 2024 Lexus IS 350 BaseIncognito 2024 Lexus IS 350 BaseIncognito 2024 Lexus IS 350 BaseIncognito 2024 Lexus IS 350 BaseIncognito 2024 Lexus IS 350 BaseIncognito 2024 Lexus IS 350 Base

    $42,194

    17,579 mi.
    Est. $770/mo

    Fred Anderson Toyota

    Check Availability
    Cape Coral, FL (48 mi)
    Quick view
  • Ultrasonic Blue Mica 2.0 2021 Lexus IS 350 Base

    $40,494

    $500
    37,360 mi.
    Est. $739/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view
  • $46,494

    16,183 mi.
    Est. $848/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view
  • Caviar 2023 Lexus IS 350 Base

    $44,994

    26,286 mi.
    Est. $821/mo

    Lexus of Fort Myers

    Check Availability
    Fort Myers, FL (49 mi)
    Quick view

About the Lexus IS 350

FAQs

How much does the Lexus IS 350 cost?

The Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the IS 350 is $38,831, with pricing starting at $5,900.

What is the MPG of the Lexus IS 350?

The Lexus IS 350 with traditional internal combustion engine offers up to 20 MPG city and 28 MPG highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus IS 350?

The Lexus IS 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus IS 350?

The Lexus IS 350 is available in the following trim levels:

Skip to Listings
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed