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  • Grecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 Base

    $33,128

    85,510 mi.
    Est. $602/mo

    DeLand Kia

    4.8
    Check Availability
    DeLand, FL (25 mi)
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  • Cloudburst Gray 2023 Lexus IS 350 BaseCloudburst Gray 2023 Lexus IS 350 BaseCloudburst Gray 2023 Lexus IS 350 BaseCloudburst Gray 2023 Lexus IS 350 BaseCloudburst Gray 2023 Lexus IS 350 BaseCloudburst Gray 2023 Lexus IS 350 Base

    $41,480

    22,184 mi.
    Est. $753/mo

    Lexus of Tampa Bay

    4.5
    Check Availability
    Free delivery from Tampa, FL (124 mi)
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  • Ultra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 BaseUltra White 2024 Lexus IS 350 Base

    $42,995

    11,134 mi.
    Est. $781/mo

    Impex Auto Sales

    4.8
    Check Availability
    $536 delivery from Greensboro, NC (471 mi)
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  • caviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Base

    $44,000

    11,913 mi.
    Est. $799/mo

    Bozard Ford

    4.9
    Check Availability
    St Augustine, FL (49 mi)
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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $35,000

    86,691 mi.
    Est. $636/mo

    Bozard Ford

    4.9
    Check Availability
    St Augustine, FL (49 mi)
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  • Ultra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 Base

    $42,998

    40,864 mi.
    Est. $781/mo

    AutoNation Acura North Orlando

    4.7
    Check Availability
    Sanford, FL (38 mi)
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  • Cloudburst Gray 2024 Lexus IS 350 BaseCloudburst Gray 2024 Lexus IS 350 BaseCloudburst Gray 2024 Lexus IS 350 BaseCloudburst Gray 2024 Lexus IS 350 BaseCloudburst Gray 2024 Lexus IS 350 BaseCloudburst Gray 2024 Lexus IS 350 Base

    $43,998

    8,526 mi.
    Est. $799/mo

    AutoNation Acura North Orlando

    4.7
    Check Availability
    Sanford, FL (38 mi)
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  • Iridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 Base

    $34,737

    $673
    55,779 mi.
    Est. $631/mo

    OFFLease Orlando

    4.1
    Check Availability
    Maitland, FL (48 mi)
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  • caviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Base

    $44,921

    15,816 mi.
    Est. $816/mo

    OFFLease Orlando

    4.1
    Check Availability
    Maitland, FL (48 mi)
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  • RED 2014 Lexus IS 350 BaseRED 2014 Lexus IS 350 BaseRED 2014 Lexus IS 350 BaseRED 2014 Lexus IS 350 BaseRED 2014 Lexus IS 350 BaseRED 2014 Lexus IS 350 Base

    $9,750

    201,301 mi.
    Est. $177/mo

    Swerve Auto LLC

    Check Availability
    Longwood, FL (43 mi)
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  • Iridium 2021 Lexus IS 350 Base

    $38,998

    22,108 mi.
    Est. $708/mo

    AutoNation USA Sanford

    3.4
    Check Availability
    Sanford, FL (38 mi)
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  • ultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Base

    $46,938

    0 mi.
    Est. $852/mo

    Lexus of Winter Park

    Check Availability
    Winter Park, FL (50 mi)
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  • ultrasonic blue 2.0 2025 Lexus IS 350 Base

    $47,033

    0 mi.
    Est. $854/mo

    Lexus of Winter Park

    Check Availability
    Winter Park, FL (50 mi)
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  • incognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Base

    $46,438

    0 mi.
    Est. $843/mo

    Lexus of Winter Park

    Check Availability
    Winter Park, FL (50 mi)
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  • caviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Base

    $46,438

    0 mi.
    Est. $843/mo

    Lexus of Winter Park

    Check Availability
    Winter Park, FL (50 mi)
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About the Lexus IS 350

FAQs

How much does the Lexus IS 350 cost?

The Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the IS 350 is $38,607, with pricing starting at $4,480.

What is the MPG of the Lexus IS 350?

The Lexus IS 350 with traditional internal combustion engine offers up to 20 MPG city and 28 MPG highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus IS 350?

The Lexus IS 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus IS 350?

The Lexus IS 350 is available in the following trim levels:

What model years are available for the Lexus IS 350?

Lexus IS 350 inventory is available for the 2021 model year.

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