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  • Satin Cashmere Metallic 2015 Lexus RX 350 BaseSatin Cashmere Metallic 2015 Lexus RX 350 BaseSatin Cashmere Metallic 2015 Lexus RX 350 BaseSatin Cashmere Metallic 2015 Lexus RX 350 BaseSatin Cashmere Metallic 2015 Lexus RX 350 BaseSatin Cashmere Metallic 2015 Lexus RX 350 Base

    $18,396

    $130
    105,419 mi.
    Est. $336/mo

    Fairway Ford, Inc.

    4.6
    Check Availability
    Greenville, SC (26 mi)

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  • Eminent White Pearl 2024 Lexus RX 350 PremiumEminent White Pearl 2024 Lexus RX 350 PremiumEminent White Pearl 2024 Lexus RX 350 PremiumEminent White Pearl 2024 Lexus RX 350 PremiumEminent White Pearl 2024 Lexus RX 350 PremiumEminent White Pearl 2024 Lexus RX 350 Premium

    $56,742

    32,753 mi.
    Est. $1,035/mo

    Fred Anderson Honda

    4.6
    Check Availability
    Greenville, SC (26 mi)
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  • Black 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 Base

    $25,489

    51,675 mi.
    Est. $465/mo

    Kevin Whitaker Chevrolet

    4.3
    Check Availability
    Greenville, SC (26 mi)
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  • EMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 Premium

    $27,995

    76,885 mi.
    Est. $511/mo

    Nodine Motor

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    Inman, SC (6 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $40,839

    61,901 mi.
    Est. $745/mo

    Auto Gallery Ford

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    Gaffney, SC (18 mi)
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  • 2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base

    $36,693

    40,979 mi.
    Est. $669/mo

    INFINITI of Greenville

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    Greenville, SC (26 mi)
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  • Iridium 2023 Lexus RX 350 PremiumIridium 2023 Lexus RX 350 PremiumIridium 2023 Lexus RX 350 PremiumIridium 2023 Lexus RX 350 PremiumIridium 2023 Lexus RX 350 PremiumIridium 2023 Lexus RX 350 Premium

    $51,145

    33,118 mi.
    Est. $933/mo

    Greenville Mitsubishi

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    Greenville, SC (26 mi)
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  • Gray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT Handling

    $41,697

    $699
    53,747 mi.
    Est. $761/mo

    Subaru of Spartanburg

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    Spartanburg, SC (7 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium Plus

    $51,536

    21,938 mi.
    Est. $940/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Atomic Silver 2017 Lexus RX 350 BaseAtomic Silver 2017 Lexus RX 350 BaseAtomic Silver 2017 Lexus RX 350 BaseAtomic Silver 2017 Lexus RX 350 BaseAtomic Silver 2017 Lexus RX 350 BaseAtomic Silver 2017 Lexus RX 350 Base

    $27,076

    102,563 mi.
    Est. $494/mo

    TLC Motors

    3.5
    Check Availability
    Moore, SC (10 mi)
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  • Caviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 Premium

    $48,536

    21,780 mi.
    Est. $885/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Blue 2017 Lexus RX 350 BaseBlue 2017 Lexus RX 350 BaseBlue 2017 Lexus RX 350 BaseBlue 2017 Lexus RX 350 BaseBlue 2017 Lexus RX 350 BaseBlue 2017 Lexus RX 350 Base

    $22,500

    110,395 mi.
    Est. $410/mo

    Sweet Rides, LLC

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    Greer, SC (18 mi)
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  • Silver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 Premium

    $22,536

    98,157 mi.
    Est. $411/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Stargazer Black 2015 Lexus RX 350 PremiumStargazer Black 2015 Lexus RX 350 PremiumStargazer Black 2015 Lexus RX 350 PremiumStargazer Black 2015 Lexus RX 350 PremiumStargazer Black 2015 Lexus RX 350 PremiumStargazer Black 2015 Lexus RX 350 Premium

    $19,136

    111,606 mi.
    Est. $349/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Matador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 Luxury

    $59,136

    20,727 mi.
    Est. $1,079/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Iridium 2024 Lexus RX 350 F SPORT HandlingIridium 2024 Lexus RX 350 F SPORT HandlingIridium 2024 Lexus RX 350 F SPORT HandlingIridium 2024 Lexus RX 350 F SPORT HandlingIridium 2024 Lexus RX 350 F SPORT HandlingIridium 2024 Lexus RX 350 F SPORT Handling

    $56,136

    30,895 mi.
    Est. $1,024/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Eminent White Pearl 2025 Lexus RX 350 Premium PlusEminent White Pearl 2025 Lexus RX 350 Premium PlusEminent White Pearl 2025 Lexus RX 350 Premium PlusEminent White Pearl 2025 Lexus RX 350 Premium PlusEminent White Pearl 2025 Lexus RX 350 Premium PlusEminent White Pearl 2025 Lexus RX 350 Premium Plus

    $62,033

    7,401 mi.
    Est. $1,132/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Matador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium Plus

    $50,536

    28,588 mi.
    Est. $922/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Gray Pearl 2023 Lexus RX 350 PremiumGray Pearl 2023 Lexus RX 350 PremiumGray Pearl 2023 Lexus RX 350 PremiumGray Pearl 2023 Lexus RX 350 PremiumGray Pearl 2023 Lexus RX 350 PremiumGray Pearl 2023 Lexus RX 350 Premium

    $48,536

    24,237 mi.
    Est. $885/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Nebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium Plus

    $45,536

    45,789 mi.
    Est. $831/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $49,136

    33,053 mi.
    Est. $896/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Caviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 Premium

    $39,536

    50,218 mi.
    Est. $721/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Matador Red Mica 2024 Lexus RX 350 Premium PlusMatador Red Mica 2024 Lexus RX 350 Premium PlusMatador Red Mica 2024 Lexus RX 350 Premium PlusMatador Red Mica 2024 Lexus RX 350 Premium PlusMatador Red Mica 2024 Lexus RX 350 Premium PlusMatador Red Mica 2024 Lexus RX 350 Premium Plus

    $54,136

    24,223 mi.
    Est. $988/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Gray Pearl 2023 Lexus RX 350 Premium PlusGray Pearl 2023 Lexus RX 350 Premium PlusGray Pearl 2023 Lexus RX 350 Premium PlusGray Pearl 2023 Lexus RX 350 Premium PlusGray Pearl 2023 Lexus RX 350 Premium PlusGray Pearl 2023 Lexus RX 350 Premium Plus

    $51,536

    24,395 mi.
    Est. $940/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (26 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 Luxury

    $50,500

    $500
    43,233 mi.
    Est. $921/mo

    Fairway Ford

    4.8
    Check Availability
    $1,256 delivery from Canfield, OH (419 mi)
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  • White 2019 Lexus RX 350White 2019 Lexus RX 350White 2019 Lexus RX 350White 2019 Lexus RX 350White 2019 Lexus RX 350White 2019 Lexus RX 350

    $29,998

    75,264 mi.
    Est. $547/mo

    CarMax Myrtle Beach

    4.8
    Check Availability
    $149 delivery to Greenville, SC (26 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $65,097
2025 Lexus RX 350 $59,442 5 Good deals

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $34,856, with pricing starting at $4,400.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2008 to 2026.

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