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  • Caviar 2017 Lexus RX 350 BaseCaviar 2017 Lexus RX 350 BaseCaviar 2017 Lexus RX 350 BaseCaviar 2017 Lexus RX 350 BaseCaviar 2017 Lexus RX 350 BaseCaviar 2017 Lexus RX 350 Base

    $20,251

    129,870 mi.
    Est. $379/mo

    Joe Machens Toyota

    4.1
    Check Availability
    Columbia, MO (27 mi)
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  • Satin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 Base

    $21,483

    101,026 mi.
    Est. $402/mo

    Joe Machens Hyundai

    4.1
    Check Availability
    Columbia, MO (27 mi)
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  • 2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base2020 Lexus RX 350 Base

    $39,800

    20,286 mi.
    Est. $745/mo

    Joe Machens Ford

    4.8
    Check Availability
    Columbia, MO (28 mi)
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  • Black 2018 Lexus RX 350 BaseBlack 2018 Lexus RX 350 BaseBlack 2018 Lexus RX 350 BaseBlack 2018 Lexus RX 350 BaseBlack 2018 Lexus RX 350 BaseBlack 2018 Lexus RX 350 Base

    $23,774

    101,841 mi.
    Est. $445/mo

    Capital City CDJR

    4.9
    Check Availability
    Jefferson City, MO (8 mi)
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  • Caviar 2022 Lexus RX 350 Base

    $33,500

    101,909 mi.
    Est. $627/mo

    Mazda of Columbia

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    Columbia, MO (27 mi)
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  • Nebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 Premium

    $48,595

    19,655 mi.
    Est. $909/mo

    Jidd Motors Mitsubishi

    4.6
    Check Availability
    $973 delivery from Des Plaines, IL (325 mi)
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  • Matador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium Plus

    $45,985

    39,753 mi.
    Est. $860/mo

    Jidd Motors Mitsubishi

    4.6
    Check Availability
    $973 delivery from Des Plaines, IL (325 mi)
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  • Silver 2019 Lexus RX 350 350Silver 2019 Lexus RX 350 350Silver 2019 Lexus RX 350 350Silver 2019 Lexus RX 350 350Silver 2019 Lexus RX 350 350Silver 2019 Lexus RX 350 350

    $25,672

    $691
    93,649 mi.
    Est. $480/mo

    Frank Leta Honda

    4.4
    Check Availability
    O'Fallon, MO (76 mi)
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  • Nori Green Pearl 2024 Lexus RX 350 Premium PlusNori Green Pearl 2024 Lexus RX 350 Premium PlusNori Green Pearl 2024 Lexus RX 350 Premium PlusNori Green Pearl 2024 Lexus RX 350 Premium PlusNori Green Pearl 2024 Lexus RX 350 Premium PlusNori Green Pearl 2024 Lexus RX 350 Premium Plus

    $53,545

    16,665 mi.
    Est. $1,002/mo

    BMW of West St. Louis

    4.9
    Check Availability
    Ballwin, MO (86 mi)
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  • Gold 2014 Lexus RX 350Gold 2014 Lexus RX 350Gold 2014 Lexus RX 350Gold 2014 Lexus RX 350Gold 2014 Lexus RX 350Gold 2014 Lexus RX 350

    $26,998

    35,765 mi.
    Est. $505/mo

    CarMax St. Louis Mid Rivers Mall

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    St. Peters, MO (82 mi)
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  • Nightfall Mica 2016 Lexus RX 350 BaseNightfall Mica 2016 Lexus RX 350 BaseNightfall Mica 2016 Lexus RX 350 BaseNightfall Mica 2016 Lexus RX 350 BaseNightfall Mica 2016 Lexus RX 350 BaseNightfall Mica 2016 Lexus RX 350 Base

    $24,495

    $500
    78,000 mi.
    Est. $458/mo

    Dave Mungenast Pre-Owned Center of Bonne Terre

    Check Availability
    Bonne Terre, MO (98 mi)
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  • Nightfall Mica 2025 Lexus RX 350 PremiumNightfall Mica 2025 Lexus RX 350 PremiumNightfall Mica 2025 Lexus RX 350 PremiumNightfall Mica 2025 Lexus RX 350 PremiumNightfall Mica 2025 Lexus RX 350 PremiumNightfall Mica 2025 Lexus RX 350 Premium

    $49,990

    $1K
    26,918 mi.
    Est. $935/mo

    Napleton's Mid Rivers Chrysler Jeep Dodge RAM Maserati Alfa Romeo

    3.9
    Check Availability
    St Peters, MO (83 mi)
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  • 0085 2024 Lexus RX 350 Luxury0085 2024 Lexus RX 350 Luxury0085 2024 Lexus RX 350 Luxury0085 2024 Lexus RX 350 Luxury0085 2024 Lexus RX 350 Luxury0085 2024 Lexus RX 350 Luxury

    $61,200

    $800
    10,661 mi.
    Est. $1,145/mo

    Spirit Lexus

    3.4
    Check Availability
    St. Louis, MO (92 mi)
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  • Caviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 Premium

    $47,000

    $1K
    24,625 mi.
    Est. $879/mo

    Spirit Lexus

    3.4
    Check Availability
    St. Louis, MO (92 mi)
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  • 08x5 2025 Lexus RX 350 Luxury08x5 2025 Lexus RX 350 Luxury08x5 2025 Lexus RX 350 Luxury08x5 2025 Lexus RX 350 Luxury08x5 2025 Lexus RX 350 Luxury08x5 2025 Lexus RX 350 Luxury

    $58,300

    $1.5K
    23,213 mi.
    Est. $1,091/mo

    Spirit Lexus

    3.4
    Check Availability
    St. Louis, MO (92 mi)
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  • Matador Red Mica 2023 Lexus RX 350 LuxuryMatador Red Mica 2023 Lexus RX 350 LuxuryMatador Red Mica 2023 Lexus RX 350 LuxuryMatador Red Mica 2023 Lexus RX 350 LuxuryMatador Red Mica 2023 Lexus RX 350 LuxuryMatador Red Mica 2023 Lexus RX 350 Luxury

    $51,000

    $600
    29,107 mi.
    Est. $954/mo

    Spirit Lexus

    3.4
    Check Availability
    St. Louis, MO (92 mi)
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  • Gold 2025 Lexus RX 350 LuxuryGold 2025 Lexus RX 350 LuxuryGold 2025 Lexus RX 350 LuxuryGold 2025 Lexus RX 350 LuxuryGold 2025 Lexus RX 350 LuxuryGold 2025 Lexus RX 350 Luxury

    $60,400

    14,429 mi.
    Est. $1,130/mo

    Spirit Lexus

    3.4
    Check Availability
    St. Louis, MO (92 mi)
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  • Claret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 Base

    $17,500

    $300
    109,292 mi.
    Est. $327/mo

    Spirit Lexus

    3.4
    Check Availability
    St. Louis, MO (92 mi)
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  • 03r1 2025 Lexus RX 350 Luxury03r1 2025 Lexus RX 350 Luxury03r1 2025 Lexus RX 350 Luxury03r1 2025 Lexus RX 350 Luxury03r1 2025 Lexus RX 350 Luxury03r1 2025 Lexus RX 350 Luxury

    $59,000

    $1.8K
    12,187 mi.
    Est. $1,104/mo

    Spirit Lexus

    3.4
    Check Availability
    St. Louis, MO (92 mi)
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About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $33,664, with pricing starting at $3,995.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2017 to 2022.

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