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  *Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
  
  
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  Used
  2021 Mercedes-Benz GLS 450
  for sale
  
  
    near
Chillum, MD 
    
  
      - Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
    
  *Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
  
  
  **Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
  
 
            
        
       
          
        
       
          
        
       
          
        
       
          
        
       
            Used
2021 Mercedes-Benz GLS 450 4MATIC
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Reviews
Lindsay VW of Dulles sales Bob Derby made my VW GLI
Lindsay VW of Dulles sales Bob Derby made my VW GLI purchase exceptional once again, as I have purchased new cars from Bob over many years. Bob is friendly and knowledgeable about the product, and represents the dealer professionally. Great experience and enjoy the vehicle! DS Leesburg, Virginia
Love this car
This car met all my needs and more. Love the interior and the way its moves. So comfortable and reliable! Very pleased with this car!
 
          
        
       
          
        
       
          
        
       
          
        
       
          
        
       
            Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
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I can’t recommend this dealership enough.
I can’t recommend this dealership enough. Trivan and the rest of his team were a pleasure to deal with from start to finish. I was treated with honesty and respect and therefore they earned my business now and in the future. Thank you for a wonderful buying experience.
Best SUV we've ever owned.
Exceptional vehicle in the SUV class. We drove the BMW X7, Audi Q7, Volvo XC90 and this GLS 450 just kept blowing them out of the water. The ride is amazing and we feel the comfort level and size is the best
 
          
        
       
          
        
       
          
        
       
          
        
       
          
        
       
            Used
2021 Mercedes-Benz GLS 450 4MATIC
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My experience with Rene the salesman was very pleasant
My experience with Rene the salesman was very pleasant and he was patient/professional. Excellent job 👍
You get what you pay for
We are in our first five months and I seriously believe all the safety options have kept me out of at least two accidents. The car on the highway practically drives itself while giving me a message. Audio systems are excellent. The 450 GLS makes driving a bit of a joy.
 
          
        
       
          
        
       
          
        
       
          
        
       
          
        
       
            Mercedes-Benz Certified
2021 Mercedes-Benz GLS 450 4MATIC
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Reviews
I had an excellent experience purchasing my Mercedes-Benz
I had an excellent experience purchasing my Mercedes-Benz with the help of Vinay Verma. From start to finish, he was professional, knowledgeable, and attentive to every detail. Vinay made the entire process seamless and stress-free, taking the time to answer all of my questions and ensuring I felt confident with my decision. His friendly demeanor and commitment to customer satisfaction truly set him apart. I highly recommend Vinay to anyone looking for a smooth and enjoyable car-buying experience!
Great car!
Luxurious to drive and very quiet riding car. I am very satisfied with the car. The electronices are a bit over whelming at first. Love the car.
 
          
        
       
          
        
       
          
        
       
          
        
       
          
        
       
            Used
2021 Mercedes-Benz GLS 450 4MATIC
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I post a review on June 7 2025 and today July 26, 2025 we
I post a review on June 7 2025 and today July 26, 2025 we had meeting with the manager James and he settled the price issue we had with the purchase of Honda civic 2016. Thank you James
Great Electronics and Engineering
This car is state of the art in human factors engineering. It has multiple layers of safety enhancements. Interior is very spacious. The 42 volt battery provides quick acceleration which allows the car to have no lag time when accelerating.
 
          
        
       
          
        
       
          
        
       
          
        
       
          
        
       
            Used
2021 Mercedes-Benz GLS 450 4MATIC
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This was my first time at this dealership for service and
This was my first time at this dealership for service and I must say 5 start service! Tonny Wambugu My Service Advisor was great and very knowledgeable about the service that was due and assisted me with the process. I will definitely recommend this Mercedes dealership to anyone who is looking to get their vehicle serviced!!
Used
2021 Mercedes-Benz GLS 450 4MATIC
Vehicle information
Features
Reviews
I?m always happy with the service?? The people are Great!
I?m always happy with the service?? The people are Great! They are prompt in explaining what needs to be done right away; as well us letting you know what is needed a little later
There are 20 matching cars close to your year range.
 
          
        
       
          
        
       
          
        
       
          
        
       
          
        
       
            Mercedes-Benz Certified
2023 Mercedes-Benz GLS 450 4MATIC
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2023 Mercedes-Benz GLS 450 Base
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2022 Mercedes-Benz GLS 450 4MATIC
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2022 Mercedes-Benz GLS 450 4MATIC
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2022 Mercedes-Benz GLS 450 4MATIC
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2020 Mercedes-Benz GLS 450 4MATIC
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            Used
2022 Mercedes-Benz GLS 450 4MATIC
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            Used
2023 Mercedes-Benz GLS 450
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            Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450 4MATIC
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            Used
2020 Mercedes-Benz GLS 450 4MATIC
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2022 Mercedes-Benz GLS 450 4MATIC
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            Used
2022 Mercedes-Benz GLS 450 4MATIC
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            Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450 4MATIC
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            Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450 4MATIC
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            Mercedes-Benz Certified
2022 Mercedes-Benz GLS 450 4MATIC
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2022 Mercedes-Benz GLS 450 4MATIC
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2022 Mercedes-Benz GLS 450
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2023 Mercedes-Benz GLS 450 4MATIC
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2020 Mercedes-Benz GLS 450 4MATIC
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Mercedes-Benz GLS 450 prices by year
| Model year | Average price | Deals | 
|---|---|---|
| 2026 Mercedes-Benz GLS 450 | $99,918 | |
| 2025 Mercedes-Benz GLS 450 | $90,717 | 6 Good deals | 
| 2024 Mercedes-Benz GLS 450 | $75,921 | 10 Good deals | 
| 2022 Mercedes-Benz GLS 450 | $54,960 | 12 Good deals | 
| 2017 Mercedes-Benz GLS 450 | $16,042 | 5 Great deals | 
About the 2021 Mercedes-Benz GLS 450
4MATIC shown (base trim).
- Seating
- 6
- Door count
- 4
- Drivetrain
- All-wheel drive
- Combined MPG
- 21
- Transmission
- 9-Speed A/T
- Engine
- 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)
 
          How much does the 2021 Mercedes-Benz GLS 450 cost?
The 2021 Mercedes-Benz GLS 450 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 GLS 450 is $40,656, with pricing starting at $28,998.
What is the MPG of the 2021 Mercedes-Benz GLS 450?
The 2021 Mercedes-Benz GLS 450 offers up to 20 MPG in city driving and 24 MPG on the highway for a combined rating of 21 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz GLS 450?
The 2021 Mercedes-Benz GLS 450 compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz GLS 450 reliable?
The 2021 Mercedes-Benz GLS 450 has an average reliability rating of 3.5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 GLS 450 owners.
Is the 2021 Mercedes-Benz GLS 450 a good SUV?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz GLS 450.
- Comfort 5.0
- Interior 4.9
- Performance 3.8
- Value 3.1
- Exterior 4.9
- Reliability 3.5
62% of drivers recommend this car
- Comfort 5.0
- Interior 4.9
- Performance 3.8
- Value 3.1
- Exterior 4.9
- Reliability 3.5
GLS 450 (1 style)
| Style | 
|---|
| GLS 450 4MATIC SUV | 
| Inventory price | 
| Starting at $76,000 | 
| Combined MPG | 
| 21 | 
| Engine | 
| 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 
    
  *Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
  
  
  **Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
  
Research the 2021 Mercedes-Benz GLS 450
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
